感官代偿在药品盲用无障碍包装设计中的应用研究

目的 针对盲人难以精准、便捷、安全服药的问题，基于感官代偿原理，研究如何利用触觉、听觉等感官代偿的潜在优势设计“适盲性”药品无障碍包装，辅助盲人实现科学、合理、精准用药。方法 基于盲人的生理和心理特点，分析药品包装在适应盲人使用时的“痛点”，在把握盲人感官代偿机理的基础上，结合具体案例，研究药品包装适盲性无障碍设计的途径和方法。结论 在基于盲人特殊的感官代偿机制设计盲用无障碍药品包装时，要理性、深度地思考如何最大限度地激发触觉和听觉的代偿潜能来解决盲人的服药障碍问题。通过简洁规范的盲文标注设计、科学合理的适盲性结构设计、智能交互的语音指令设计等方式，改善药品包装的核心信息呈现方式，提升药品信息传递的便捷性和准确性，使盲人能够独立自主地识药、取药和服药。     

基于面元素重排的三维网格模型数据隐藏算法

目的 为了解决目前三维数据隐藏算法不能兼顾无失真和盲提取的问题，提出一种新的完全无失真的三维网格模型数据隐藏盲算法。方法 首先使用混沌逻辑映射选择嵌入与提取模式，保证数据的安全性。然后利用面元素重排，完全不会造成三维模型失真的性质，通过不同嵌入模式规则对三角面元素进行重排，以嵌入秘密数据。接收端则可根据相应的提取模式规则提取秘密数据。结果 仿真结果与分析表明，该算法不会对三维模型造成任何失真，嵌入容量为每顶点2比特，且能抵抗仿射变换攻击、噪声攻击和平滑攻击等。结论 这种三维数据隐藏盲算法无失真，容量大、安全性高、鲁棒性强，适用于三维载体不容修改的情形，如军事、医学、秘密通信和版权保护等。     

Controlled growth of Bi-Functional La doped CeO2 nanorods for photocatalytic H2 production and supercapacitor applications

The rapid increase in energy consumption has severely rehabilitated human life urging to develop reliable and environmental friendly energy storage devices. Target oriented, systematic approach has been adopted to synthesis La doped CeO₂ nanostructures with percentage as La_xCe_1-xO₂ (X = 0,1,3,5,7) for potential super capacitors applications. Morphological doping impact on H₂ production, electrochemical and optical properties are thoroughly investigated. XRD studies revealed the crystalline phase purity and attained approximately 35 nm average crystallite size. The SEM images exposed that primary morphology nano-particles has been tuned into nanorods by increasing the La concentration in CeO₂ with size range 40～60 nm. CV graphs depicted that the prepared electrodes obey the pseudo capacitive faradaic reactions behavior in nature. Maximum capacitance (925 F g^-1) has been achieved by La_0·05Ce_0·95O₂ which is better than numerous reported materials. The La_0·05Ce_0·95O₂ also exhibited excellent GCD stability with 87.8% retention exhibiting it suitability for supercapacitor applications. Furthermore, the La_0·05Ce_0·95O₂ showed the significantly higher H₂ (9 μmol h^?1g^?1) production rate as compared to undoped CeO₂ and La_0·01Ce_0·99O_2, La_0·03Ce_0·97O₂ samples. This higher production is attributed to the recombination rate and have strong substantial correlation with optical characteristics.     

Designing amorphous formulations of polyphenols with naringin by spray-drying for enhanced solubility and permeability

Naringin (NAR), a major flavanone (FVA) glycoside, is a component of food mainly obtained from grapefruit. We used NAR as a food additive to improve the solubility and permeability of hydrophobic polyphenols used as supplements in the food industry. The spray-dried particles (SDPs) of NAR alone show an amorphous state with a glass transition temperature (T_g) at 93.2 °C. SDPs of hydrophobic polyphenols, such as flavone (FVO), quercetin (QCT), naringenin (NRG), and resveratrol (RVT) were prepared by adding varying amounts of NAR. All SDPs of hydrophobic polyphenols with added NAR were in an amorphous state with a single T_g, but SDPs of hydrophobic polyphenols without added NAR showed diffraction peaks derived from each crystal. The SDPs with NAR could keep an amorphous state after storage at a high humidity condition for one month, except for SDPs of RVT/NAR. SDPs with NAR enhanced the solubility of hydrophobic polyphenols, especially NRG solubility, which was enhanced more than 9 times compared to NRG crystal. The enhanced solubility resulted in the increased membrane permeability of NRG. The antioxidant effect of the hydrophobic NRG was also enhanced by the synergetic effect of NAR. The findings demonstrated that NAR could be used as a food additive to enhance the solubility and membrane permeability of hydrophobic polyphenols.     

Combination of dynamic features with a new mask to optimize neural network speech enhancement

Concerning the problem that the Neural Network speech enhancement algorithm cannot fully represent the nonlinear structure of speech due to feature selection,which leads to speech distortion.This paper proposes the combination of dynamic features with a new mask to optimize neural network speech enhancement.First,three features of noisy speech are extracted and spliced to obtain static features.Then,the first and second difference derivatives are obtained to capture the instantaneous signals of speech and fuse them into dynamic features.The combination of dynamic and static features completes internal complementarity of features and reduced speech distortion.Second,in order to enhance the intelligibility and clarity of speech at the same time,an adaptive mask is proposed,which can adjust the energy ratio of speech and noise as well as the ratio of the traditional mask and the square root mask.The Gammatone channel weight is used to modify the mask value in each channel to simulate the human auditory system and further improve the speech intelligibility.Finally,the simulation of multiple voices under different noise backgrounds shows that compared with different literature algorithms,the algorithm has a higher SNR,subjective speech quality and short-term objective intelligibility,which verifies the effectiveness of the algorithm.     

基于机器学习识别与标记分水岭分割的盲道图像定位

视觉导盲仪是一种旨在解决盲人出行困难的导盲设备，为了实现视觉导盲仪诱导盲人找到盲道并沿盲道行走，提出了一种基于机器学习识别与标记分水岭分割的盲道图像定位算法，通过离线训练与在线的识别、分割来定位盲道区域。首先对盲道图像进行视角变换的预处理，根据盲道的地面方程将变化的倾斜视角转换为固定的俯视视角，消除射影变换带来的失真；然后利用局部二进制模式描述子提取鸟瞰图的纹理特征，以自适应增强学习算法离线训练盲道识别分类器；进而利用分类器对鸟瞰图像进行在线识别，粗略确定盲道区域；最后将识别结果进行形态学处理后作为标记，利用标记分水岭算法得到精确分割的盲道区域并定位盲道中心线。在研制的视觉导盲仪上进行验证，结果表明盲道定位准确率达到了95.44%，速度平均每秒8帧，具有高准确率的同时达到实时性要求，为盲道的准确三维定位提供了必要条件。     

Red-shift and improved afterglow of Sr3Al2-xBxO5Cl2:Eu2+, Dy3+ phosphors via a cation substitution strategy

Sr₃Al_2-xB_xO₅Cl₂:Eu²⁺, Dy³⁺ (x = 0, 0.2, 0.4) long persistent phosphors were prepared via solid-state process. The pristine Sr₃Al₂O₅Cl₂:Eu²⁺, Dy³⁺ phosphor exhibits orange/red broad band emission around 609 nm, which can be attributed to the electric radiation transitions 4f⁶5 d¹→4f⁷ of Eu²⁺. Upon the same excitation, the B³⁺-doped Sr₃Al_2-xB_xO₅Cl₂:Eu²⁺, Dy³⁺ phosphors display red-shift from 609 nm to 625 nm with increasing B³⁺ concentrations. The XRD patterns show that Al³⁺ can be replaced by B³⁺ in the host lattice at the tetrahedral site, which causes lattice contraction and crystal field enhancement, and thereafter achieves the red-shift on the emission spectrum. The XPS investigation provides direct evidence of the dominant 2-valent europium in the phosphor, which can be ascribed for the broad band emission of the prepared phosphors. The afterglow of all phosphors show standard double exponential decay behavior, and the afterglow of Sr₃Al₂O₅Cl₂:Eu²⁺, Dy³⁺is rather weak, while the sample co-doped with B³⁺shows longer and stronger afterglow, as confirmed after the curve simulation. The analysis of thermally stimulated luminescence showed that, when B³⁺ is introduced, a much deeper trap is created, and the density of the electron trap is also significantly increased. As a result, B³⁺ ions caused redshift and enhanced afterglow for the Sr₃Al_2-xB_xO₅Cl₂:Eu²⁺, Dy³⁺ phosphor.     

Learn from the past – sequentially one-to-one video deblurring network

With the growing availability of hand-held cameras in recent years, more and more images and videos are taken at any time and any place. However, they usually suffer from undesirable blur due to camera shake or object motion in the scene. In recent years, a few modern video deblurring methods are proposed and achieve impressive performance. However, they are still not suitable for practical applications as high computational cost or using future information as input. To address the issues, we propose a sequentially one-to-one video deblurring network (SOON) which can deblur effectively without any future information. It transfers both spatial and temporal information to the next frame by utilizing the recurrent architecture. In addition, we design a novel Spatio-Temporal Attention module to nudge the network to focus on the meaningful and essential features in the past. Extensive experiments demonstrate that the proposed method outperforms the state-of-the-art deblurring methods, both quantitatively and qualitatively, on various challenging real-world deblurring datasets. Moreover, as our method deblurs in an online manner and is potentially real-time, it is more suitable for practical applications.     

基于小波变换的分数阶微分算法在肝脏肿瘤CT图像纹理增强中的应用

图像纹理增强过程中容易丢失平滑区域纹理细节，而分数阶微分增强虽然能够非线性保留平滑区域纹理细节，但对频率分辨率敏感。针对这个问题，提出一种基于小波变换的分数阶微分纹理增强算法，应用于平扫计算机断层扫描（CT）图像的肝脏肿瘤区域的纹理增强。首先，通过小波变换将图像感兴趣区分解成多个子带分量；其次，基于分数阶微分定义构造一个带补偿参数的分数阶微分掩膜；最后，使用该掩膜与每个高频子带分量进行卷积并利用小波逆变换重组图像感兴趣区。实验结果表明，该方法在使用较大分数阶次显著增强肿瘤区域的高频轮廓信息的同时，有效地保留了低频平滑的纹理细节：增强后的肝细胞癌区域与原区域相比，信息熵平均增加36.56%，平均梯度平均增加321.56%，平均绝对差值平均为9.287；增强后的肝血管瘤区域与原区域相比，信息熵平均增加48.77%，平均梯度平均增加511.26%，平均绝对差值平均为14.097。     

Enhancement of optical emission generated from femtosecond double-pulse laser-induced glass plasma at different sample temperatures in air

In double-pulse laser-induced breakdown spectroscopy(DP-LIBS), the collinear femtosecond double-pulse laser configuration is experimentally investigated with different initial sample temperatures using a Ti:sapphire laser. The glass sample is ablated to produce the plasma spectroscopy. During the experiment, the detected spectral lines include two Na(I) lines(589.0 nm and 589.6 nm) and one Ca(I) line at the wavelength of 585.7 nm. The emission lines are measured at room temperature(22 ℃) and three higher initial sample temperatures(T_s?=?100 ℃, 200 ℃, and 250 ℃). The inter-pulse delay time ranges from-250 ps to 250 ps.The inter-pulse delay time and the sample temperature strongly influence the spectral intensity,and the spectral intensity can be significantly enhanced by increasing the sample temperature and selecting the optimized inter-pulse time. For the same inter-pulse time of 0 ps(single-pulse LIBS), the enhancement ratio is approximately 2.5 at T_s?=?200 ℃ compared with that obtained at T_s?=?22 ℃. For the same inter-pulse time of 150 ps, the enhancement ratio can be up to 4 at T_s?=?200 ℃ compared with that obtained at T_s?=?22 ℃. The combined enhancement effects of the different initial sample temperatures and the double-pulse configuration in femtosecond LIBS are much stronger than that of the different initial sample temperatures or the double-pulse configuration only.