Machine independent AND and OR parallel execution of logicprograms. I. The binding environment

We describe a binding environment for the AND and OR parallel execution of logic programs that is suitable for both shared and nonshared memory multiprocessors. The binding environment was designed with a view of rendering a compiler using this binding environment machine independent. The binding environment is similar to closed environments proposed by J. Conery. However, unlike Conery's scheme, it supports OR and independent AND parallelism on both types of machines. The term representation, the algorithms for unification and the join algorithms for parallel AND branches are presented in this paper. We also detail the differences between our scheme and Conery's scheme. A compiler based on this binding environment has been implemented on a platform for machine independent parallel programming called the Chare Kernel     

Minimum-phase filter design from linear-phase startpoint viabalanced model truncation

A new practical design approach for minimum-phase FIR or IIR filters, setting out from a high dimensionality FIR linear-phase prototype is described. The novelty of this technique lies in overcoming the inherent problem of finding the roots of a high order polynomial with repeated and/or very closely clustered roots     

Air flow through a non-airconditioned bus with open windows

Open window buses without air-conditioning are a major mode of urban and inter-city transport in most countries. High occupancy combined with hot and humid conditions makes travel in these buses quite uncomfortable. In this study air flow through a bus has been studied that could be the basis for low cost and eco-friendly methods of increasing passenger comfort and possibly reduce drag. The aerodynamics of such a road vehicle has not been studied as previous investigations have been confined to vehicles with closed windows that present a smooth exterior to air flow. Using a 1:25 scaled Perspex model of an urban bus in Delhi, flow visualization was performed in a water channel. The Reynolds numbers were one-tenth of a real bus moving at 10 m/s. Smoke and tuft visualizations were also performed on an urban bus at 40 km/h. Numerical simulations were performed at the actual Reynolds number. Even though there were Reynolds number differences, the broad features were similar. Air enters the bus from the rear windows, moves to the front (relative to the bus) and exits from the front windows. Inside air velocity relative to the bus is about one-tenth of the free-stream velocity. The flow is highly three-dimensional and unsteady.     

Some theorems on Walsh transforms of quantizer differential andintegral nonlinearity

Methods for diagnosing weight coefficient tolerances of quantizers are derived, based on the assumption of known and available data about the quantizer's nonlinearities. Two of the methods are direct and based on the Householder orthogonalization, applied to an overdetermined equation system containing data about differential or integral nonlinearities. The remaining two methods are indirect and are based on two theorems that use the Walsh transformation on the quantizer's differential or integral nonlinearities. The language MATLAB has been used to good effect for simulation of these techniques     

Reperfusion injury delays healing of intestinal anastomosis in a rat

This SAEM position paper clarifies the role of emergency medicine in health care delivery. It builds upon the working definition of emergency medicine developed by the American College of Emergency Physicians in 1994 by describing the health care role of emergency physicians (EPs). EPs are first-contact providers who care for all patients regardless of age, gender, time of presentation, or ability to pay. They remain the only continuously accessible specialty for patients seeking help and solace in the health care system. They are an essential link in the health care continuum between primary care physicians, specialists, the out-of-hospital system, the patient, inpatient services, and communication services. The EP's role is in organizing and monitoring the emergency care delivery system. Part of this role is to better align the health care provider training and ability with the specific medical needs of a patient. The emergency health care system remains the essential medical safety net for all individuals needing care in this country.     

Age and ethnicity affect the risk and outcome of focal segmental glomerulosclerosis

In patients with proteinuria, African-American (AA) ethnicity is reported to be a risk factor for focal segmental glomerulosclereosis (FSGS) and its progression to end-stage renal disease (ESRD). We reviewed our single-center experience to determine the probability of FSGS and its progression to ESRD based on ethnicity and age at presentation in children with proteinuria with or without nephrotic syndrome. Proteinuria without systemic disease or acute glomerulonephritis was the presenting feature in 17% (236/1,403) of children in the renal patient database of Texas Children's Hospital, Baylor College of Medicine. Histopathological diagnoses were established in 107 of 236 patients (45%). FSGS was identified in 65 patients, accounting for 28% of all patients with proteinuria and 61% of patients who underwent renal biopsy. FSGS was more prevalent in AA (45%) than in non-AA patients (22%) (P=0.001), and AA patients with FSGS were older at presentation (12.7+/-4.4 years) than non-AA patients (5.6+/-4.6 years) (P<0.001). Among patients who underwent renal biopsy, increasing age at presentation increased the probability of having FSGS in AA but not non-AA patients (P=0.04). Five-year actuarial renal survival of FSGS was worse in AA (8%) than in non-AA patients (31%) (P=0.01). These data suggest an increased risk and worse outcome of FSGS in AA compared with non-AA children.     

Thrombospondin-1 CD47 Signalling: From Mechanisms to Medicine

Recent advances provide evidence that the cellular signalling pathway comprising the ligand-receptor duo of thrombospondin-1 (TSP1) and CD47 is involved in mediating a range of diseases affecting renal, vascular, and metabolic function, as well as cancer. In several instances, research has barely progressed past pre-clinical animal models of disease and early phase 1 clinical trials, while for cancers, anti-CD47 therapy has emerged from phase 2 clinical trials in humans as a crucial adjuvant therapeutic agent. This has important implications for interventions that seek to capitalize on targeting this pathway in diseases where TSP1 and/or CD47 play a role. Despite substantial progress made in our understanding of this pathway in malignant and cardiovascular disease, knowledge and translational gaps remain regarding the role of this pathway in kidney and metabolic diseases, limiting identification of putative drug targets and development of effective treatments. This review considers recent advances reported in the field of TSP1-CD47 signalling, focusing on several aspects including enzymatic production, receptor function, interacting partners, localization of signalling, matrix-cellular and cell-to-cell cross talk. The potential impact that these newly described mechanisms have on health, with a particular focus on renal and metabolic disease, is also discussed.     

Property stabilization in filled,drawn polyethylene

Mechanical properties of high density polyethylene (HDPE) extended to draw ratios in the 20–40 range have been determined and compared with corresponding properties of the polymers containing particulates including rutile, carbon black, iron oxide, and mica. Shrinkage of drawn structures was studied to temperatures near the fusion of the polymer host. The degree of interaction at polymer/additive interfaces was varied by surface coating certain of the solids with standard coupling agents. Solids were found to increase tensile moduli and to decrease shrinkage, particularly at higher exposure temperatures. The magnitude of changes due to the presence of solids was shown to depend on the apparent interaction at contacts between host and additive. In a dispersion–force matrix, like HDPE, benefits were optimized when the particulates were amphoteric or neutral, rather than having pronounced acid or base interaction potentials.     

A piezoelectric model based multi-objective optimization of robot gripper design

The field of robotics is evolving at a very high pace and with its increasing applicability in varied fields, the need to incorporate optimization analysis in robot system design is becoming more prominent. The present work deals with the optimization of the design of a 7-link gripper. As actuators play a crucial role in functioning of the gripper, the actuation system (piezoelectric (PZ), in this case) is also taken into consideration while performing the optimization study. A minimalistic model of PZ actuator, consisting different series and parallel assembly arrangements for both mechanical and electrical parts of the PZ actuators, is proposed. To include the effects of connector spring, the relationship of force with actuator displacement is replaced by the relation between force and the displacement of point of actuation at the physical system. The design optimization problem of the gripper is a non-linear, multi modal optimization problem, which was originally formulated by Osyczka (2002). In the original work, however, the actuator was a ‘constant output-force actuator model’ providing a constant output without describing the internal structure. Thus, the actuator model was not integrated in the optimization study. Four different cases of the PZ modelling have been solved using multi-objective evolutionary algorithm (MOEA). Relationship between force and actuator displacement is obtained using each set of non-dominated solutions. These relationships can provide a better insight to the end user to select the appropriate voltage and gripper design for specific application.     

Indium selenide microrod films: chemical bath deposition from acidic bath

Films of indium selenide was deposited onto glass and indium tin oxide coated glass substrates in acidic medium using chemical bath deposition at room temperature. Indium sulphate and sodium selenosulphate were used as precursors of In³⁺ and Se^2?, respectively. The structural, surface morphological and optical properties of the deposited films were studied. Diffractograms in structural study revealed the deposited material is In₂Se₃ films. Controlled bath conditions resulted in the evolution of the In₂Se₃ microrod-like morphology. The optical band gap of the film was found to be 1.7 eV.