神经网络建模的变量聚类分析方法

针对神经网络建模需尽量减少输入变量及输入变量要充分解释输出变量的问题，研究了变量聚类分析方法，提出了变量选取原则并对这些原则进行了基于信息论的理论推导，开发了基于聚类分析的神经网络软件。实际应用表明，这种基于精确数学分析进行的神经网络变量的选取是行之有效的。     

浆态床重油改质技术新进展

浆态床加氢工艺是一种重要的劣质重油/渣油轻质化技术,随着原油的劣质化和产品的清洁化,其重要性凸显,各大石油公司均大力研究和开发。本文重点介绍了典型浆态床加氢工艺(包括Eni公司的EST、Chevron公司的VRSH、UOP公司的UniflexTM等)的技术特征和进展情况。在详细分析浆态床加氢反应机理的基础上,指出了其未来的研究方向:研究重油反应过程的胶体稳定性以控制生焦;开发新型高效催化剂以降低成本;研究浆态床反应器流体力学和传质特性以指导工程放大。     

钼/活性炭渣油加氢催化剂的硫化

钼/活性炭催化剂是一种新型渣油加氢催化剂,其硫化效果直接决定着催化剂的活性和稳定性。实验考察了硫化条件对钼/活性炭催化剂（Mo/AC）硫化度的影响,运用X射线衍射（XRD）、X射线光电子能谱（XPS）、扫描电子显微镜（SEM）和透射电镜（TEM）等手段对硫化态催化剂进行了表征。结果表明,以二硫化碳为硫化剂,正十六烷为硫化介质,在硫化温度350 ℃,硫化时间3 h,氢气初压6 MPa条件下催化剂硫化度为85%,活性相MoS2堆垛结构为4～6层,晶片长度为6～10 nm,分布比较均匀,具有良好的加氢活性。     

苏丹6区稠油破乳剂筛选和应用研究

随着苏丹6区油田稠油开采不断进行,原油乳化严重,破乳脱水更加困难,FNE和MOGA区块的稠油脱后含水率超标,严重影响原油外输。采用瓶试法对16种破乳剂进行了室内评价筛选,结果表明:破乳剂T611对FNE和MOGA区块原油的脱水效果最好,且随着破乳剂加药浓度增加,脱水率增大。将筛选出来的破乳剂T611在FNE和MOGA FPF进行了现场应用试验,试验结果表明:破乳剂加药质量浓度约为50 mg/L时,7 d内FNE和MOGA FPF外输原油含水率都在1%左右,破乳剂T611现场应用效果较好,可以满足生产要求。     

Full structure building and docking of NifS from extremophile Acidithiobacillus ferrooxidans

The gene iscS-2 from extremophile Acidithiobacillus ferrooxidans may play a crucial role in nitrogenase maturation. To investigate the protein encoded by this gene, a reliable integral three-dimensional molecular structure was built. The obtained structure was further used to search binding sites, carry out the flexible docking with cofactor pyridoxal 5＇-phosphate（PLP） and substrate cysteine, and identify its key residues. The docking results of PLP reveal that the residues of Lys203, His100, Thr73, Ser200, His202, Asp177 and GlnlS0 have large interaction energies and/or hydrogen bonds fixation with PLP. The docking results of cysteine show that the amino group in cysteine is very near His100, Lys203 and PLP, and the interaction energies for cysteine with them are very big. These identified residues are in line with the experimental facts of NifS from other sources. Moreover, the four residues of Asn152, Val179, Ala102 and Met148 in the PLP docking and the two residues of Lys208 and Alal02 in the cysteine docking also have large interaction energies, which are fitly conserved in NifS from all kinds of sources but have not been identified before, According to these results, this gene encodes NifS protein, and the substrate cysteine can be effectively recruited into the active site. Furthermore, all of the above detected key residues are directly responsible for the binding and/or catalysis of PLP and cysteine.     

基于B/S模式的嵌入式远程医疗监护系统

文中设计了一种基于B/S模式的实时远程医疗监护系统,整个系统由嵌入式生理信息采集系统和客户端浏览器构成,实现基于Internet的多病人生理参数远程实时监护。客户端采用B/S架构,无需安装任何客户端软件,只要打开浏览器就可以实时查看和发送生理参数和波形。设计分析结果表明,系统方案简单,工作稳定,经试验测试达到了预期的效果。     

船载便携式水位突变预警仪研制

针对因水电站黑起动等特殊运行工况引发的水位突变,使所在水域停泊的船舶易发生翻沉、搁浅等情况,开发并研制出了船载便携式水位突变预警仪。该预警仪以单片机为控制核心,由温度测试电路、超声波发射接收电路、数据显示电路及报警电路组成,可实时监测船舶干舷高度、横倾斜度及所在水域的水位变率。当船舶所在水域水位发生突变且船舶干舷高度、横倾斜度及水位变率中任一项或全部超过了安全限值,预警仪会自动发出警报,同时,将这3个值的变化情况及时反馈给船员,警示船员调整船舶姿态,从而能更好地保证停靠船舶在水位突变情况下的安全。相对于传统预警系统,该预警仪具有造价低、体积小、质量轻、安装简便等优点,可以广泛应用于水位突变预警及其所在水域行进或停泊船舶的安全监控。     

基于BIM协同设计的住宅方案节能优化研究

BIM技术为解决建筑业存在的问题提供了新的途径。以住宅楼设计为例介绍基于BIM协同设计的节能优化具体应用流程。通过方案节能优化前后的能耗分析和成本分析,体现BIM技术较传统模式节能优化在协同性、模型准确性、效率等方面的优势和应用价值。     

提高泥岩高边坡绿化植被成活率

通过改进,泥岩高边坡客土绿化植被成活率明显提高,为了保证泥岩高边坡客土绿化植被成活率的稳定、保证其不反弹,根据重新优化的高边坡客土施工工艺,编制了作业指导书,用于指导后续高边坡客土边坡绿化的施工,并对高边坡客土绿化施工相关人员再次进行了交底培训;固定了边坡客土绿化施工管理及作业人员,强调了质量责任制,要求严格按照作业指导书实施,切实把控好后续边坡客土绿化植被的成活率。     

Purification and enzymatic characteristics of cysteine desulfurase, IscS, in Acidithiobacillus ferrooxidans ATCC 23270

A cysteine desulfurase protein, IscS, was encoded by the operon iscSUA in Acidithiobacillusferrooxidans. The gene of IscS from Acidithiobacillus ferrooxidans ATCC 23270 was cloned and expressed in Escherichia coil The protein was purified by one-step affinity chromatography to homogeneity. The final protein yield after affinity chromatography was 12.9%. The enzyme was characterized for thermal stability, pH and kinetic parameters. The molecular mass of recombinant lscS was 46 ku by SDS-PAGE. The optimum pH was 8.0-8.5. The enzyme had a temperature optimum at 30 ℃ and was relatively stable at 40 ℃, with 67% loss of activity. 1,5-I-AEDANS significantly inhibited IscS activity. Kinetic parameters Km and Vmax were found to be 0.11 mmol/L and 2.57 μmol/（L.min）.