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排序方式: 共有363条查询结果,搜索用时 15 毫秒
1.
Gina Cavaliere Giovanna Trinchese Nadia Musco Federico Infascelli Chiara De Filippo Vincenzo Mastellone Valeria Maria Morittu Pietro Lombardi Raffaella Tudisco Micaela Grossi Vincenzo Monda Monica I. Cutrignelli Antonietta Messina Serena Calabrò Heleena B. Moni Luigi Stradella Giovanni Messina Marcellino Monda Maria Pina Mollica 《Journal of dairy science》2018,101(3):1843-1851
Excessive energy intake may evoke complex biochemical processes characterized by inflammation, oxidative stress, and impairment of mitochondrial function that represent the main factors underlying noncommunicable diseases. Because cow milk is widely used for human nutrition and in food industry processing, the nutritional quality of milk is of special interest with respect to human health. In our study, we analyzed milk produced by dairy cows fed a diet characterized by a high forage:concentrate ratio (high forage milk, HFM). In view of the low n-6:n-3 ratio and high content of conjugated linoleic acid of HFM, we studied the effects of this milk on lipid metabolism, inflammation, mitochondrial function, and oxidative stress in a rat model. To this end, we supplemented for 4 wk the diet of male Wistar rats with HFM and with an isocaloric amount (82 kJ, 22 mL/d) of milk obtained from cows fed a diet with low forage:concentrate ratio, and analyzed the metabolic parameters of the animals. Our results indicate that HFM may positively affect lipid metabolism, leptin:adiponectin ratio, inflammation, mitochondrial function, and oxidative stress, providing the first evidence of the beneficial effects of HFM on rat metabolism. 相似文献
2.
3.
Ginevra Salerno 《International journal for numerical methods in engineering》1992,35(7):1351-1395
Structures presenting kinematical inderterminacy are usually called mechanisms. This paper is entirely concerned with assemblies which reveal themselves to be mechanisms at a null value of the load. Among them a first distinction is made between infinitesimal and finite ones, the former being characterized by one or several directions of lower (but not zero) stiffness, whereas the latter show at least one finite admissible displacement for which none of the bars undergoes any elongation. Moreover, there exists the possibility to make a further distinction among the infinitesimal mechanisms, according to which is the order of the stiffness along the direction considered above. The way of evaluating this order is to perform a local analysis of the strain energy of the assembly, once the displacement field is parametrized in terms of a suitable parameter. By means of a finite element technique, this analysis can be easily performed through the numerical approach presented in this report. 相似文献
4.
Distributed Coordination and Workflow on the World Wide Web 总被引:5,自引:0,他引:5
Antonietta Grasso Jean-Luc Meunier Daniele Pagani Remo Pareschi 《Computer Supported Cooperative Work (CSCW)》1997,6(2-3):175-200
This paper describes WebFlow, an environment thatsupports distributed coordination services on theWorld Wide Web. WebFlow leverages the HTTP Webtransport protocol and consists of a number of toolsfor the development of applications that require thecoordination of multiple, distributed servers.Typical applications of WebFlow include distributeddocument workspaces, inter/intra-enterprise workflow,and electronic commerce. In this paper we describe thegeneral WebFlow architecture for distributedcoordination, and then focus on the environment fordistributed workflow. 相似文献
5.
Schilling D.L. Milstein L.B. Pickholtz R.L. Bruno F. Kanterakis E. Kullback M. Erceg V. Biederman W. Fishman D. Salerno D. 《Communications Magazine, IEEE》1991,29(11):86-93
Multipath propagation in a broadband CDMA environment is described. A propagation model for broadband spread-spectrum signals is presented. Experimental results relating to the sharing of the band by fixed service microwave users and mobile personal communications network (PCN) users are discussed. Field tests indicate that PCN systems can provide high-quality communications when sharing the spectrum with fixed-service microwave systems in suburban and urban areas 相似文献
6.
M Salerno 《Canadian Metallurgical Quarterly》1991,44(8):5292-5297
7.
Valeria Ciaffaglione Prof. Maria N. Modica Prof. Valeria Pittalà Prof. Giuseppe Romeo Prof. Loredana Salerno Dr. Sebastiano Intagliata 《ChemMedChem》2021,16(23):3496-3512
The development of potent antitumor agents with a low toxicological profile against healthy cells is still one of the greatest challenges facing medicinal chemistry. In this context, the “mutual prodrug” approach has emerged as a potential tool to overcome undesirable physicochemical features and mitigate the side effects of approved drugs. Among broad-spectrum chemotherapeutics available for clinical use today, 5-fluorouracil (5-FU) is one of the most representative, also included in the World Health Organization model list of essential medicines. Unfortunately, severe side effects and drug resistance phenomena are still the primary limits and drawbacks in its clinical use. This review describes the progress made over the last ten years in developing 5-FU-based mutual prodrugs to improve the therapeutic profile and achieve targeted delivery to cancer tissues. 相似文献
8.
Maria?Antonietta BresciaEmail author Vincenzo?Mazzilli Angela?Sgaramella Stefano?Ghelli Francesco?Paolo Fanizzi Antonio?Sacco 《Journal of the American Oil Chemists' Society》2004,81(5):431-436
Characterization of the lipid fraction of raw cow and buffalo milk samples, collected in different breeding areas in Apulia,
a region of southern Italy, were performed by means of 1H NMR. The aim of this work was to establish whether FA composition data obtained by 1H NMR can be used in the differentiation of buffalo and cow milk samples according to species. A complete assignment of the
signals present in the spectrum was attempted by COSY, heteronuclear coherence spectra. Quantification of FA was carried out
by inserting the integrals of particular peaks in suitable calculations. Multivariate statistical analysis, conducted on the
results of the quantification, permitted buffalo and cow milks to be distinguished. 相似文献
9.
Gianmarco de Felice Maria Antonietta Aiello Carmelo Caggegi Francesca Ceroni Stefano De Santis Enrico Garbin Natalino Gattesco Łukasz Hojdys Piotr Krajewski Arkadiusz Kwiecień Marianovella Leone Gian Piero Lignola Claudio Mazzotti Daniel Oliveira Corina Papanicolaou Carlo Poggi Thanasis Triantafillou Maria Rosa Valluzzi Alberto Viskovic 《Materials and Structures》2018,51(4):95
Textile Reinforced Mortar (TRM), also known as Fabric Reinforced Mortar or Fabric Reinforced Cementitious Matrix, composites are an emerging technology for the external repair and strengthening of existing structures. For most applications, the effectiveness of the TRM reinforcement relies on its bond performance. This recommendation identifies the best practice to characterize the bond behaviour of TRM. A shear bond test method is proposed to determine the peak axial stress (associated with the maximum load that can be transferred from the structural member to the externally bonded TRM reinforcement), the stress–slip relationship and the failure mode that controls the TRM-to-substrate load transfer capacity. Guidelines on specimen manufacturing, experimental setup, test execution, and determination of test results are provided. 相似文献
10.
Consideration was given to the discrete-time MAP/G/1/∞ queuing system where the arriving customer is taken to the server with a certain probability depending only of the processed
length of the customer in service and squeezes out its predecessor to the first place on the queue or, with the complementary
probability, occupies the first place on the queue (inversive probabilistic servicing discipline). For this system, the main
stationary operational characteristics were established. 相似文献