LLDPE with Exclusively Ethyl Branches by Tandem Catalysis with Single-Site Zr(IV)/Co(II) Catalysts

Semicrystalline linear low density polyethylenes (LLDPEs) with exclusively ethyl branching (from 7 to 56 branches per 1,000 carbon atoms) were prepared from ethylene by homogeneous tandem catalytic systems comprising (imino)pyridine cobalt(II) dichlorides as oligomerization precursors, bis(cyclopentadienyl)zirconium(IV) dichloride as copolymerization precursor and methyaluminoxane as activator. The activity of the tandem systems was evaluated by varying either the molar fraction of the cobalt precursors or the ethylene pressure. The latter parameter was of crucial importance to control both the productivity and the extent of 1-butene incorporation. In particular, increasing the ethylene pressure from 2 bar to 4 bar changed the “comonomer effect” from positive to negative.     

Infrared and nuclear magnetic resonance of maleic anhydride copolymers and their half esters

Infrared and NMR group-type methods for the analysis of the anhydride content of maleic anhydride copolymers such as poly(maleic anhydride-co-α-olefin) and the half ester content of their reaction products with alcohols are described. The infrared analyses are based on the integrated absorptivities of the anhydride carbonyl and the combination of the acid and ester carbonyl. The NMR method is based on the intensities of the various chemically shifted groups in the copolymer. The use of dimethyl sulfoxide as an auxiliary solvent has made the infrared analysis possible.     

Measurement-device-independent quantum key distribution: from idea towards application

We assess the overall performance of our quantum key distribution (QKD) system implementing the measurement-device-independent (MDI) protocol using components with varying capabilities such as different single-photon detectors and qubit preparation hardware. We experimentally show that superconducting nanowire single-photon detectors allow QKD over a channel featuring 60 dB loss, and QKD with more than 600 bits of secret key per second (not considering finite key effects) over a 16 dB loss channel. This corresponds to 300 and 80 km of standard telecommunication fiber, respectively. We also demonstrate that the integration of our QKD system into FPGA-based hardware (instead of state-of-the-art arbitrary waveform generators) does not impact on its performance. Our investigation allows us to acquire an improved understanding of the trade-offs between complexity, cost and system performance, which is required for future customization of MDI-QKD. Given that our system can be operated outside the laboratory over deployed fiber, we conclude that MDI-QKD is a promising approach to information-theoretic secure key distribution.     

Osthol Ameliorates Kidney Damage and Metabolic Syndrome Induced by a High-Fat/High-Sugar Diet

Excessive intake of fructose results in metabolic syndrome (MS) and kidney damage, partly mediated by its metabolism by fructokinase-C or ketohexokinase-C (KHK-C). Osthol has antioxidant properties, is capable of regulating adipogenesis, and inhibits KHK-C activity. Here, we examined the potential protective role of osthol in the development of kidney disease induced by a Western (high-fat/high-sugar) diet. Control rats fed with a high-fat/high-sugar diet were compared with two groups that also received two different doses of osthol (30 mg/kg/d or 40 mg/kg/d body weight BW). A fourth group served as a normal control and received regular chow. At the end of the follow-up, kidney function, metabolic markers, oxidative stress, and lipogenic enzymes were evaluated. The Western diet induced MS (hypertension, hyperglycemia, hypertriglyceridemia, obesity, hyperuricemia), a fall in the glomerular filtration rate, renal tubular damage, and increased oxidative stress in the kidney cortex, with increased expression of lipogenic enzymes and increased kidney KHK expression. Osthol treatment prevented the development of MS and ameliorated kidney damage by inhibiting KHK activity, preventing oxidative stress via nuclear factor erythroid 2-related factor (Nrf2) activation, and reducing renal lipotoxicity. These data suggest that the nutraceutical osthol might be an ancillary therapy to slow the progression of MS and kidney damage induced by a Western diet.     

Cortical Responses in Rats Predict Perceptual Sensitivities to Complex Sounds.

The common assumption that perceptual sensitivities are related to neural representations of sensory stimuli has seldom been directly demonstrated. The authors analyzed the similarity of spike trains evoked by complex sounds in the rat auditory cortex and related cortical responses to performance in an auditory task. Rats initially learned to identify 2 highly different periodic, frequency-modulated sounds and then were tested with increasingly similar sounds. Rats correctly classified most novel sounds; their accuracy was negatively correlated with acoustic similarity. Rats discriminated novel sounds with slower modulation more accurately than sounds with faster modulation. This asymmetry was consistent with similarities in cortical representations of the sounds, demonstrating that perceptual sensitivities to complex sounds can be predicted from the cortical responses they evoke. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Auditory Categorization of Complex Sounds by Rats (Rattus norvegicus).

Little research has explored the auditory categorization abilities of mammals. To better understand these processes, the authors tested the abilities of rats (Rattus norvegicus) to categorize multidimensional acoustic stimuli by using a classic category-learning task developed by R. N. Shepard, C. I. Hovland, and H. M. Jenkins (1961). Rats proved to be able to categorize 8 complex sounds on the basis of either the direction or rate of frequency modulation but not on the basis of the range of frequency modulation. Rats' categorization abilities were limited but improved slowly and incrementally, suggesting that learning was not facilitated by selective attention to acoustic dimensions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The easy-to-hard effect in human (Homo sapiens) and rat (Rattus norvegicus) auditory identification.

The authors examined whether progressively training humans and rats to perform a difficult auditory identification task led to larger improvements than extensive training with highly similar sounds (the easy-to-hard effect). Practice improved humans' ability to distinguish sounds regardless of the training regimen. However, progressively trained subjects were more accurate and showed more generalization, despite significantly less training with the stimuli that were the most difficult to distinguish. Rats showed less capacity to improve with practice but still benefited from progressive training. These findings indicate that transitioning from an easier to a more difficult task during training can facilitate, and in some cases may be essential for, auditory perceptual learning. The results are not predicted by an explanation that assumes interaction of generalized excitation and inhibition but are consistent with a hierarchical account of perceptual learning in which the representational precision required to distinguish stimuli determines the mechanisms engaged during learning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Green-blue luminescence dichroism of cyano-containing poly[(m-phenylene ethynylene)-alt-(p-phenylene ethynylene)] aggregates dispersed in oriented polyethylene

A new highly luminescent cyano-containing poly[(m-phenylene ethynylene)-alt-(p-phenylene ethynylene)] derivative (CN-PPE) has been prepared and blended in micro/nano-sized dispersions into linear low density polyethylene (LLDPE) films by melt-processing. CN-PPE macromolecules show pronounced tendency to form molecular aggregates in the excited state when dispersed in the polymer matrix with emission characteristics depending on the structural order of the luminescent chromophores. In CN-PPE/LLDPE films, the polymer matrix orientation induces effective anisotropic arrangements of the π-π staking interactions between luminescent guest aggregates, thereby generating a pronounced green-blue dichroic emission. The capability to easily modulate the luminescent properties of polyethylene films (from green to blue reversibly) simply by varying CN-PPE concentration or by stretching the polymer matrix, suggests various technological applications in the field of smart and intelligent films from thermoplastic materials.