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排序方式: 共有170条查询结果,搜索用时 265 毫秒
1.
Addresses the question of whether a "rigid molecule" (one which does not deform in an external field) used as the conducting channel in a standard three-terminal MOSFET configuration can offer any performance advantage relative to a standard silicon MOSFET. A self-consistent solution of coupled quantum transport and Poisson's equations shows that even for extremely small channel lengths (about 1 nm), a "well-tempered" molecular FET demands much the same electrostatic considerations as a "well-tempered" conventional MOSFET. In other words, we show that just as in a conventional MOSFET, the gate oxide thickness needs to be much smaller than the channel length (length of the molecule) for the gate control to be effective. Furthermore, we show that a rigid molecule with metallic source and drain contacts has a temperature independent subthreshold slope much larger than 60 mV/decade, because the metal-induced gap states in the channel prevent it from turning off abruptly. However, this disadvantage can be overcome by using semiconductor contacts because of their band-limited nature. 相似文献
2.
Microsystem Technologies - A physics-based Quantum-Modified CLassical Drift–Diffusion (QMCLDD) non-linear mathematical model has been developed for design and characterisation of GaN/AlGaN... 相似文献
3.
Kundu Abhijit Adhikari Saikat Das Arnima Kanjilal Maitreyi Ray Mukherjee Moumita 《Microsystem Technologies》2021,27(2):569-584
Microsystem Technologies - Photo-sensors are integral part of different bio-medical diagnostic equipment. Each type of bio-molecules possess unique spectral fingerprint in visible wavelength region... 相似文献
4.
Biswas Uttara Rakshit Jayanta Kumar Das Joyashree Bharti Gaurav Kumar Suthar Bhuvneshwer Amphawan Angela Najjar Monia 《SILICON》2021,13(3):885-892
Silicon - In the present report, a photonic crystal based micro-ring resonator (MRR) structure is proposed which is very compact in size and has very fast response and is employed for temperature... 相似文献
5.
Synergistic Effect of PVDF-Coated PCL-TCP Scaffolds and Pulsed Electromagnetic Field on Osteogenesis
Yibing Dong Luvita Suryani Xinran Zhou Padmalosini Muthukumaran Moumita Rakshit Fengrui Yang Feng Wen Ammar Mansoor Hassanbhai Kaushik Parida Daniel T. Simon Donata Iandolo Pooi See Lee Kee Woei Ng Swee Hin Teoh 《International journal of molecular sciences》2021,22(12)
Bone exhibits piezoelectric properties. Thus, electrical stimulations such as pulsed electromagnetic fields (PEMFs) and stimuli-responsive piezoelectric properties of scaffolds have been investigated separately to evaluate their efficacy in supporting osteogenesis. However, current understanding of cells responding under the combined influence of PEMF and piezoelectric properties in scaffolds is still lacking. Therefore, in this study, we fabricated piezoelectric scaffolds by functionalization of polycaprolactone-tricalcium phosphate (PCL-TCP) films with a polyvinylidene fluoride (PVDF) coating that is self-polarized by a modified breath-figure technique. The osteoinductive properties of these PVDF-coated PCL-TCP films on MC3T3-E1 cells were studied under the stimulation of PEMF. Piezoelectric and ferroelectric characterization demonstrated that scaffolds with piezoelectric coefficient d33 = −1.2 pC/N were obtained at a powder dissolution temperature of 100 °C and coating relative humidity (RH) of 56%. DNA quantification showed that cell proliferation was significantly enhanced by PEMF as low as 0.6 mT and 50 Hz. Hydroxyapatite staining showed that cell mineralization was significantly enhanced by incorporation of PVDF coating. Gene expression study showed that the combination of PEMF and PVDF coating promoted late osteogenic gene expression marker most significantly. Collectively, our results suggest that the synergistic effects of PEMF and piezoelectric scaffolds on osteogenesis provide a promising alternative strategy for electrically augmented osteoinduction. The piezoelectric response of PVDF by PEMF, which could provide mechanical strain, is particularly interesting as it could deliver local mechanical stimulation to osteogenic cells using PEMF. 相似文献
6.
Sheetal Rani Basundhara Dasgupta Gaurav Kumar Bhati Kalpana Tomar Dr. Sabyasachi Rakshit Dr. Subhabrata Maiti 《Chembiochem : a European journal of chemical biology》2021,22(7):1113-1113
Evolutionarily elderly proteins commonly feature greater catalytic promiscuity. Cytochrome c is among the first set of proteins in evolution to have known prospects in electron transport and peroxidative properties. Here, we report that cyt c is also a proficient proton-transfer catalyst and enhances the Kemp elimination (KE; model reaction to show proton transfer catalytic property) by ∼750-fold on self-organized systems like micelles and vesicles. The self-organized systems mimic the mitochondrial environment in vitro for cyt c. Using an array of biophysical and biochemical mutational assays, both acid–base and redox mechanistic pathways have been explored. The histidine moiety close to hemin group (His18) is mainly responsible for proton abstraction to promote the concerted E2 pathway for KE catalysis when cyt c is in its oxidized form; this has also been confirmed by a H18A mutant of cyt c. However, the redox pathway is predominant under reducing conditions in the presence of dithiothreitol over the pH range 6–7.4. Interestingly, we found almost 750-fold enhanced KE catalysis by cyt c compared to aqueous buffer. Overall, in addition to providing mechanistic insights, the data reveal an unprecedented catalytic property of cyt c that could be of high importance in an evolutionary perspective considering its role in delineating the phylogenic tree and also towards generating programmable designer biocatalysts. 相似文献
7.
Microsystem Technologies - Absorptive and dispersive properties of atmospheric hydrometeors, affect the propagation of millimetre-wave and submillimeter wave signals. In adverse weather condition,... 相似文献
8.
Sanjoy Chakraborty Apu Kumar Saha Ratul Chakraborty Moumita Saha Sukanta Nama 《国际智能系统杂志》2022,37(1):52-104
The search for food stimulated by hunger is a common phenomenon in the animal world. Mimicking the concept, recently, an optimization algorithm Hunger Games Search (HGS) has been proposed for global optimization. On the other side, the Whale Optimization Algorithm (WOA) is a commonly utilized nature-inspired algorithm portrayed by a straightforward construction with easy parameters imitating the hunting behavior of humpback whales. However, due to minimum exploration of the search space, WOA has a high chance of trapping into local solutions, and more exploitation leads it towards premature convergence. The concept of hunger from HGS is merged with the food searching techniques of the whale to lessen the inherent drawbacks of WOA. Two weights of HGS are adaptively designed for every whale using the respective hunger level for balancing search strategies. Performance verification of the proposed hunger search-based whale optimization algorithm (HSWOA) is done by comparing it with 10 state-of-the-art algorithms, including three very recently developed algorithms on 30 classical benchmark functions. Comparison with some basic algorithms, recently modified algorithms, and WOA variants is performed using IEEE CEC 2019 function set. Statistical performance of the proposed algorithm is verified with Friedman's test, boxplot analysis, and Nemenyi multiple comparison test. The operating speed of the algorithm is determined and tested with complexity analysis and convergence analysis. Finally, seven real-world engineering problems are solved and compared with a list of metaheuristic algorithms. Numerical and statistical performance comparison with state-of-the-art algorithms confirms the efficacy of the newly designed algorithm. 相似文献
9.
Our study illustrates the development of a microfluidics (MF) platform combining fluorescence microscopy and femtosecond/picosecond-resolved spectroscopy to investigate ultrafast chemical processes in liquid-phase diffusion-controlled reactions. By controlling the flow rates of two reactants in a specially designed MF chip, sub-100 ns time resolution for the exploration of chemical intermediates of the reaction in the MF channel has been achieved. Our system clearly rules out the possibility of formation of any intermediate reaction product in a so-called fast ionic reaction between sodium hydroxide and phenolphthalein, and reveals a microsecond time scale associated with the formation of the reaction product. We have also used the developed system for the investigation of intermediate states in the molecular recognition of various macromolecular self-assemblies (micelles) and genomic DNA by small organic ligands (Hoechst 33258 and ethidium bromide). We propose our MF-based system to be an alternative to the existing millisecond-resolved "stopped-flow" technique for a broad range of time-resolved (sub-100 ns to minutes) experiments on complex chemical∕biological systems. 相似文献
10.
Automatic generation of fuzzy rule base and membership functions from an input-output data set, for reliable construction of an adaptive fuzzy inference system, has become an important area of research interest. We propose a new robust, fast acting adaptive fuzzy pattern classification scheme, named influential rule search scheme (IRSS). In IRSS, rules which are most influential in contributing to the error produced by the adaptive fuzzy system are identified at the end of each epoch and subsequently modified for satisfactory performance. This fuzzy rule base adjustment scheme is accompanied by an output membership function adaptation scheme for fine tuning the fuzzy system architecture. This iterative method has shown a relatively high speed of convergence. Performance of the proposed IRSS is compared with other existing pattern classification schemes by implementing it for Fisher's iris data problem and Wisconsin breast cancer data problems. 相似文献