Differential transforming growth factor-beta secretion in adenocarcinoma and squamous cell carcinoma of the uterine cervix

Tumor cells from eight freshly isolated cervical cancers (i.e., four adenocarcinomas and four squamous carcinomas) were analyzed for their production of the immune-inhibitory cytokine transforming growth factor-beta (TGF-beta) in vitro. All fresh adenocarcinomas secreted significant levels of TGF-beta (mean 397, range between 207 and 782 pg/ml/10(5) cells/48 hr). In contrast, no detectable TGF-beta was present in the supernatants from the four fresh squamous carcinoma cultures (P < 0.001). These data suggest that major differences in the secretion of the immunoinhibitory cytokine TGF-beta exist between squamous cell carcinomas and adenocarcinomas of the uterine cervix. Furthermore, these findings suggest that at least some of the differences in the natural biologic behavior, as well as in the response to radiation treatment, between these two histologic types of cervical cancer could be related to differences in secretion of this immune-inhibitory cytokine.     

Theoretical and experimental analyses of rheological,compatibility and mechanical properties of PVMQ/XNBR-g GMA/XNBR/GO ternary hybrid nanocomposites

Iranian Polymer Journal - Effects of graphene oxide (GO) on various properties of rubber hybrid nanocomposites based on PVMQ/XNBR-g-GMA/XNBR (phenyl-vinyl-methyl-polysiloxane/carboxylated nitrile...     

Discharge suppression in the silent interval preceding the tone burst in pause-build units of the dorsal cochlear nucleus of the unanesthetized decerebrate cat

A recent intracellular study of dorsal cochlear nucleus (DCN) neurons in vitro by Manis [P. B. Manis, J. Neurosci. 10, 2338-2351 (1990)] suggests that the expression of the pause-build discharge pattern is in large part dependent on hyperpolarization of their membrane potentials in a period just preceding a depolarizing stimulus ("hyperpolarization conditioning" hypothesis). Our examination of the activity of a sample of pause-build units (n = 72) revealed suppression of discharge activity during a time window of the silent interstimulus interval (SII) just preceding the tone burst relative to the spontaneous rate in 74% of all units. The discharge suppression of a subset of DCN pause-build units in the SII satisfies a requirement of the "hyperpolarization conditioning" hypothesis, and thus supports the hypothesis.     

Coating Effects on Transient Cooling a Hot Spherical Body

A numerical solution is carried out to treat the transient cooling problem with conduction and radiation for a hot spherical body covered with a cold coating material. The solution includes the equations of radiative transfer, coupled with a transient energy equation that contains both radiative and conductive terms. The radiative transfer equation was solved by the discrete ordinates method, and a parmetric study was performed by changing various physical parameters such as the optical thicknesses, thermal conductivity of the coating, emissivity, and diffusivity of the sphere. It was found that the properties of the coating have a direct effect on the cooling rate of the sphere.     

Influence of the underneath cavity on buoyant‐forced cooling of the integrated photovoltaic panels in building roof: a thermography study

Airflow around building‐integrated photovoltaics (BIPV) has a significant impact on their hygrothermal behavior and degradation. The potential of reducing the temperature of BIPV using an underneath cavity is experimentally and numerically investigated in literature. Most of the models are oversimplified in terms of modeling the impact of 3D flow over/underneath of PV modules, which can result in a non‐uniform surface temperature and consequently a non‐homogenous thermal degradation. Moreover, the simultaneous presence of radiation and convection related to upstream wind, in addition to the combined impact of back‐ventilation and surface convection, is barely addressed in literature. However, these simplifications can result in the unrealistic loading climate conditions. This paper aims to present a unique experimental setup to provide more realistic climate conditions for investigating the ventilation potential of the underneath. The setup consists of a solar simulator and a building prototype with installed PV, placed inside an atmospheric wind tunnel to control upstream wind velocity. Thermography is performed using an infrared camera to monitor the surface temperature of the BIPV. The potential of an underneath cavity with various cavity heights and PV arrangement is further investigated in this paper. The outcome would be eventually useful in the development of practical guidelines for BIPV installation. Copyright © 2013 John Wiley & Sons, Ltd.     

A waste heat recovery system development and analysis using ORC for the energy efficiency improvement in aluminium electrolysis cells

The present work investigates an active waste heat recovery system for the side walls of the aluminium electrolysis cells, enabling utilization of the extracted heat in power generation. This will potentially lead to energy efficiency improvement in the primary aluminium production industry and an enhanced aluminium production rate. An experimentally validated loop thermosyphon heat pipe model was used for heat extraction from the cell side wall. Boosting system thermal efficiency through waste heat recovery, by means of a heat utilization system, and increasing the level of control, as well as thermal equilibrium, stand as the main addressed objectives of the current study, which consequently result in an increased aluminium production rate. An organic Rankine cycle is incorporated into the system, and its performance is evaluated, taking into consideration the operating situations in terms of available temperature and thermal power range.     

Real-time face detection and lip feature extraction using field-programmable gate arrays.

This paper proposes a new technique for face detection and lip feature extraction. A real-time field-programmable gate array (FPGA) implementation of the two proposed techniques is also presented. Face detection is based on a naive Bayes classifier that classifies an edge-extracted representation of an image. Using edge representation significantly reduces the model's size to only 5184 B, which is 2417 times smaller than a comparable statistical modeling technique, while achieving an 86.6% correct detection rate under various lighting conditions. Lip feature extraction uses the contrast around the lip contour to extract the height and width of the mouth, metrics that are useful for speech filtering. The proposed FPGA system occupies only 15050 logic cells, or about six times less than a current comparable FPGA face detection system.     

Mental health services in Louisiana school-based health centers post-Hurricanes Katrina and Rita.

Following Hurricanes Katrina and Rita, Louisiana school-based health centers (SBHCs) were called on to respond to a sharp increase in mental health needs, especially for displaced students coping with grief, loss, trauma, and uncertainty. To assess the impact of the hurricanes on the students and the needs of SBHC mental health providers (MHPs), we surveyed MHPs in each of the SBHCs under the auspices of the Louisiana Department of Health and Hospitals, Office of Public Health. SBHC practitioners from around the state reported that mental health service utilization rose during the 2005-2006 school year, but utilization of services increased most significantly in schools receiving the majority of displaced students. Anxiety and adjustment problems were noted as increasing the most following the hurricanes. A multitude of other conditions was also reported. By the time of this survey in April 2006, the reported prevalence of most symptoms had declined, but all remained above their pre-hurricane levels. Self-reported needs of SBHC MHPs are also discussed in light of the major natural disasters. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The TASSO vertex detector

The design, construction and performance of a small pressurized drift chamber of low mass and high wire density is described. The chamber forms part of the TASSO experiment at the PETRA e⁺e⁻ storage ring of the DESY Laboratory. First physics results obtained with the chamber are also briefly discussed.