Rheological behavior of neat and carbon fiber-reinforced poly(ether ketone ketone) for extrusion deposition additive manufacturing

To develop new materials for extrusion additive manufacturing (AM) systems, a fundamental understanding of rheological properties is essential to correlate the effect of processing on material structure and its properties. In this work, the rheological properties of five different grades of neat and carbon fiber (CF)-reinforced poly(ether ketone ketone) are reported. Rheological properties are essential to understand the effect of reinforcing fibers and AM process parameters such as time, temperature, environment, and shear rate on flow behavior during processing. Small-amplitude oscillatory shear tests and steady shear tests indicated neat grades to exhibit less increase in viscosity over time when processed in air than the CF-filled grades. The filled grades showed greater shear thinning and lower sensitivity to temperature. Overall, this rheological analysis provides a broad framework for determining appropriate processing conditions for extrusion deposition AM of such high-temperature polymer systems.     

Proton-Detected Solid-State NMR of the Cell-Free Synthesized α-Helical Transmembrane Protein NS4B from Hepatitis C Virus

Proton-detected 100 kHz magic-angle-spinning (MAS) solid-state NMR is an emerging analysis method for proteins with only hundreds of microgram quantities, and thus allows structural investigation of eukaryotic membrane proteins. This is the case for the cell-free synthesized hepatitis C virus (HCV) nonstructural membrane protein 4B (NS4B). We demonstrate NS4B sample optimization using fast reconstitution schemes that enable lipid-environment screening directly by NMR. 2D spectra and relaxation properties guide the choice of the best sample preparation to record 2D ¹H-detected ¹H,¹⁵N and 3D ¹H,¹³C,¹⁵N correlation experiments with linewidths and sensitivity suitable to initiate sequential assignments. Amino-acid-selectively labeled NS4B can be readily obtained using cell-free synthesis, opening the door to combinatorial labeling approaches which should enable structural studies.     

Changes in precipitation and corrosion characteristics of 18/10Ti austenitic stainless steel exposed to prolonged annealing at 750–850 °C

This investigation deals with the analysis of intergranular acicular precipitations by X-ray diffraction techniques and SEM. Results obtained during analysing acicular precipitate in 18/10Ti steel, isothermally annealed at 750–850 °C, can be summarised as follows: Intergranular needles are constituted by a complex phosphide of M₂P type whose chemical composition can be written as (Ti,Cr,Fe,Ni)₂P. Crystal growth direction of intergranular acicular M₂P particles in austenite is 〈 100 〉_γ. The following orientation relationship was determined between the complex phosphide of M₂P type and austenite: . Corrosion testing in boiling 65% HNO₃ revealed that there was a relationship between the occurrence of acicular precipitate and a reduction in corrosion rate to a level below 0.5 g m^?2h^?1.     

Structural optimization of Z-axis tuning-fork MEMS gyroscopes for enhancing reliability and resolution

Inertial sensors such as gyroscopes and accelerometers are normally considered as the most important sensors in a navigation system. Especially in the underwater or under-ice applications, the accuracy of the entire navigation system has to mainly rely on the precision of the inertial sensors due to inapplicability of global positioning systems. For MEMS-based inertial sensors, fabrication variation and environmental disturbance are among the major error sources. To address these challenges, in this paper we propose an optimization methodology by using parametric analysis on a reference design for improving sensor reliability and resolution. Apart from studying the resolution improvement by deploying an alternative sensing scheme, the effects of changing location, shape, and size of critical cantilevers have been thoroughly explored. By using this method, we have derived an improved mechanical structure for tuning-fork gyroscopes. Our numerical analyses show that the bandwidth of the proposed structure, which is the most important stability measure in the vibratory gyroscopes with slightly mismatched resonant frequencies, is over 1.7 times more immune to fabrication imperfection than the other structural alternatives. The drive and sense resonant amplitude robustness against fabrication imperfection is also improved in the proposed structure. In addition, this structure is able to provide at least 2.3 times larger sense-mode capacitance response to external rotation compared to the previously published designs. More important, it is observed that there is always non-negligible room for improving performance of gyroscopes if our proposed structural optimization methodology is integrated into the conventional MEMS-based inertial sensor design flow.     

Market opportunity recognition in the Chilean wine industry: traditional versus relational marketing approaches

The aim of this paper is to examine how wine firms implement their marketing strategies based on the recognition of market opportunities by their Chief Executive Officers (CEOs). Firstly, we describe the marketing activities in 69 traditional Chilean wine firms. Then, in-depth interviews with CEOs of two wineries are analysed using cognitive maps to uncover the cognitive processes responsible for recognizing and executing market activities. Our findings indicate that there is a similar set of strategic resources across the wineries, but the CEOs’ different perceptions of the usefulness of these resources in the implementation of marketing strategies have led them to select diverse strategies to increasing both the price per bottle and wine sales. This paper makes two contributions. Firstly, we compare the benefit of implementing traditional and relational marketing strategies in the Chilean wine industry. Secondly, we show that the CEOs’ perception of feedback processes among the available resources affects the recognition of market opportunities and the marketing strategy in wine firms.     

Actor networks and the construction of applicable knowledge: the case of the Timbre Brownfield Prioritization Tool

This article deals with experiences acquired during the process of developing the Timbre Brownfield Prioritization Tool (TBPT). Developing a decision support tool that takes into account the expectations and experiences of its potential users is similar to creating applicable knowledge by the joint action of scientists and heterogeneous actors. Actor network theory is used to explore the construction of this form of applicable knowledge as a process of actor network creation. Following the French sociologist Callon, networks are seen to be initiated and carried out by a group of scientists (tool developers) via four moments of translation, called problematization, interessement, enrolment and mobilization. Each step in the construction of the TBPT—from the initial research question to the final model—can be linked in retrospect to changing configurations of actor networks. Based on the experiences of the tool developers in the Czech Republic, Poland, Germany and Romania, we illustrate how these configurations varied across space and time. This contribution emphasizes the ability to correlate gains in knowledge with the more visible changes in the scope of actor networks in order to highlight achievements but also limitations in acquiring applicable knowledge.     

Monooxime‐monocarbamoyl Bispyridinium Xylene‐Linked Reactivators of Acetylcholinesterase—Synthesis,In vitro and Toxicity Evaluation,and Docking Studies

Acetylcholinesterase (AChE) reactivators are crucial antidotes to organophosphate intoxication. A new series of 26 monooxime‐monocarbamoyl xylene‐linked bispyridinium compounds was prepared and tested in vitro, along with known reactivators (pralidoxime, HI‐6, obidoxime, trimedoxime, methoxime, K107, K108 and K203), on a model of tabun‐ and paraoxon‐, methylparaoxon‐ and DFP‐inhibited human erythrocyte AChE. Although their ability to reactivate tabun‐inhibited AChE did not exceed that of the previously known compounds, some newly prepared compounds showed promising reactivation of pesticide‐inhibited AChE. The acute toxicity of the novel compounds was also determined. Docking studies using tabun‐inhibited AChE were performed for three compounds of interest. The structure–activity relationship (SAR) study confirmed the apparent influence of the xylene linkage and carbamoyl moiety on the reactivation ability and toxicity of the agents.     

Microbial activity in soil enriched with preparations of AS-lignin and lignofulvonic acid

In chernozem soil, enriched with preparations of AS-lignin or lignofulvonic acid, an increased production of carbon dioxide was observed during a 4-week incubation, and, as compared with the non-amended control, an increased number of bacteria but not of actinomycetes was detected. Increased numbers of fungi were detected only in the variant with AS-lignin at the end of the incubation. The relative incidence of bacteria utilizing vanillin, syringic acid or protocatechuic acid as the only carbon sources increased in the enriched medium. Oxidation of vanillic acid, syringic acid and to a lesser extent of coumarin increased in suspensions of soils incubated with AS-lignin or fulvic acid. The results obtained indicate that bacteria are involved in the mineralization of the added substrates and confirm the relationship between metabolism of these compounds and simple aromatic derivatives.     

The Power of Commuting with Finite Sets of Words

We construct a finite language L such that the largest language commuting with L is not recursively enumerable. This gives a negative answer to the question raised by Conway in 1971 and also strongly disproves Conway's conjecture on context-freeness of maximal solutions of systems of semi-linear inequalities.     

0-1背包问题贪婪算法应用研究

结合生活中顾客中奖后奖品的选择问题,给出0-1背包问题的数学模型,介绍基于0-1背包问题的的贪婪算法,使用这种算法解决奖品选择问题,最后在viusal c 6.0下编程实现.