Interaction of guided light in rib polymer waveguides with dielectrophoretically controlled nanoparticles

This work demonstrates an optofluidic system, where dielectrophoretically controlled suspended nanoparticles are used to manipulate the properties of an optical waveguide. This optofluidic device is composed of a multimode polymeric rib waveguide and a microfluidic channel as its upper cladding. This channel integrates dielectrophoretic (DEP) microelectrodes and is infiltrated with suspended silica and tungsten trioxide nanoparticles. By applying electrical signals with various intensities and frequencies to the DEP microelectrodes, the nanoparticles can be concentrated close to the waveguide surface significantly altering the optical properties in this region. Depending on the particle refractive indices, concentrations, positions and dimensions, the light remains confined or is scattered into the surrounding media in the microfluidic channel.     

Cylindrical functionally graded shell model based on the first order shear deformation nonlocal strain gradient elasticity theory

Microsystem Technologies - In this article, a cylindrical functionally graded shell model is developed in the framework of nonlocal strain gradient theory for the first time. For this purpose, the...     

Dielectrophoretically assembled particles: feasibility for optofluidic systems

This work presents the dielectrophoretic manipulation of sub-micron particles suspended in water and the investigation of their optical responses using a microfluidic system. The particles are made of silica and have different diameters of 600, 450, and 250 nm. Experiments show a very interesting feature of the curved microelectrodes, in which the particles are pushed toward or away from the microchannel centerline depending on their levitation heights, which is further analyzed by numerical simulations. In doing so, applying an AC signal of 12 V_p–p and 5 MHz across the microelectrodes along with a flow rate of 1 μl/min within the microchannel leads to the formation of a tunable band of particles along the centerline. Experiments show that the 250 nm particles guide the longitudinal light along the microchannel due to their small scattering. This arrangement is employed to study the feasibility of developing an optofluidic system, which can be potentially used for the formation of particles-core/liquid-cladding optical waveguides.     

Minimizing torque ripple in a brushless DC motor with fuzzy logic: applied to control rod driving mechanism of MNSR

A permanent magnet BLDC(brushless direct current) motor is used to move the control rod of a miniature neutron source reactor(MNSR). The BLDC motor drive is modeled using MATLAB/SIMULINK. Two main parts of the modeling are the inverter switching and the current control. Current control with chopping used to minimize the torque ripple of the MNSR control rod drive. Fuzzy logic current control together with soft chopping control shows the best response of all the three strategies. The prototype drive mechanism has an ATmega32 controller and power MOSFET switches. The simulation results are compared with experimental drive mechanism.     

Interfacing cell-based assays in environmental scanning electron microscopy using dielectrophoresis

Development of the dielectrophoretic (DEP) live cell trapping technology and its interfacing with the environmental scanning electron microscopy (ESEM) is described. DEP microelectrode arrays were fabricated on glass substrate using photolithography and lift-off. Chip-based arrays were applied for ESEM analysis of DEP-trapped human leukemic cells. This work provides proof-of-concept interfacing of the DEP cell retention and trapping technology with ESEM to provide a high-resolution analysis of individual nonadherent cells.     

Dynamic analysis of drug-induced cytotoxicity using chip-based dielectrophoretic cell immobilization technology

Quantification of programmed and accidental cell death provides useful end-points for the anticancer drug efficacy assessment. Cell death is, however, a stochastic process. Therefore, the opportunity to dynamically quantify individual cellular states is advantageous over the commonly employed static, end-point assays. In this work, we describe the development and application of a microfabricated, dielectrophoretic (DEP) cell immobilization platform for the real-time analysis of cancer drug-induced cytotoxicity. Microelectrode arrays were designed to generate weak electro-thermal vortices that support efficient drug mixing and rapid cell immobilization at the delta-shape regions of strong electric field formed between the opposite microelectrodes. We applied this technology to the dynamic analysis of hematopoietic tumor cells that represent a particular challenge for real-time imaging due to their dislodgement during image acquisition. The present study was designed to provide a comprehensive mechanistic rationale for accelerated cell-based assays on DEP chips using real-time labeling with cell permeability markers. In this context, we provide data on the complex behavior of viable vs dying cells in the DEP fields and probe the effects of DEP fields upon cell responses to anticancer drugs and overall bioassay performance. Results indicate that simple DEP cell immobilization technology can be readily applied for the dynamic analysis of investigational drugs in hematopoietic cancer cells. This ability is of particular importance in studying the outcome of patient derived cancer cells, when exposed to therapeutic drugs, as these cells are often rare and difficult to collect, purify and immobilize.     

An Investigation on Reasons Causing Inferiority in Unlubricated Sliding Wear Performance of 60NiTi as Compared to 440C Steel

60NiTi is gaining recognition as an alternative to 440C steel in ball bearing components due to its intrinsic corrosion resistance and unusually high static load capacity. 440C steel and 60NiTi exhibit comparable Rockwell hardness and would be expected to exhibit similar sliding wear behavior using hardness based models. However, results show that under unlubricated sliding conditions, 60NiTi shows inferior wear properties than 440C steel. In this study, a series of indentation and single pass scratching experiments are conducted to elucidate the reasons behind this unexpected observation. Moreover, sliding wear tests carried out under moderate and extreme tensile stress conditions were used to identify sliding conditions under which these materials exhibit similar and dissimilar behavior. The results show that 440C steel exhibits more microscopic plasticity than 60NiTi, halting the propagation of generated tensile microcracks. In contrast, the intrinsic brittleness of 60NiTi leads to the formation and growth of microcracks between the shear bands causing subsequent wear particle generation. These lead to the occurrence of wear through more aggressive abrasion processes in 60NiTi than 440C steel. These findings help explain why 60NiTi performs well when lubricated. 60NiTi is expected to tolerate ～912?MPa tensile stress before yielding. Under good lubricated conditions where a perfect lubricating film is formed, friction induced tensile stresses fall below the tensile strength of 60NiTi and wear is prevented. However, inadequate lubrication combined with high contact stress leads to damage and wear.     

A hybrid recommendation system based on profile expansion technique to alleviate cold start problem

Multimedia Tools and Applications - Recommender systems are one of the information filtering tools which can be employed to find interest items of users. Collaborative filtering is one of the...