Ir(III) and Ru(II) Complexes in Photoredox Catalysis and Photodynamic Therapy: A New Paradigm towards Anticancer Applications

Individually, photoredox catalysis (PC) and photodynamic therapy (PDT) are well-established concepts that have experienced a remarkable resurgence in recent years, leading to significant progress in organic synthesis for PC and clinical approval of anticancer drugs for PDT. But, very recently, new photoredox catalyst systems based on Ir(III) and Ru(II) complexes have garnered significant interest because they can simultaneously be used as PDT agents apart from their demonstrated PC activity. This highlight discusses the unique PC behavior of emerging Ir(III)- and Ru(II)-based systems while also examining their potential PDT activity in cancer treatment.     

Electrophoretic deposition of graphene oxide on carbon brush as bioanode for microbial fuel cell operated with real wastewater

Microbial fuel cell (MFC) is a promising technology for simultaneous wastewater treatment and energy harvesting. The properties of the anode material play a critical role in the performance of the MFC. In this study, graphene oxide was prepared by a modified hummer's method. A thin layer of graphene oxide was incorporated on the carbon brush using an electrophoretic technique. The deoxygenated graphene oxide formed on the surface of the carbon brush (RGO-CB) was investigated as a bio-anode in MFC operated with real wastewater. The performance of the MFC using the RGO-CB was compared with that using plain carbon brush anode (PCB). Results showed that electrophoretic deposition of graphene oxide on the surface of carbon brush significantly enhanced the performance of the MFC, where the power density increased more than 10 times (from 33 mWm^?2 to 381 mWm^?2). Although the COD removal was nearly similar for the two MFCs, i.e., with PCB and RGO-CB; the columbic efficiency significantly increased in the case of RGO-CB anode. The improved performance in the case of the modified electrode was related to the role of the graphene in improving the electron transfer from the microorganism to the anode surface, as confirmed from the electrochemical impedance spectroscopy measurements.     

Effects of feeding bentonite clay upon ochratoxin A–induced immunosuppression in broiler chicks

A presence of mycotoxins in feed is one of the most alarming issues in the poultry feed industry. Ochratoxins, produced by several Aspergillus and Penicillium species, are important mycotoxin regarding the health status of poultry birds. Ochratoxins are further classified into to several subtypes (A, B, C, etc) depending on their chemical structures, but ochratoxin A (OTA) is considered the most important and toxic. Bentonite clay, belonging to phyllosilicates and formed from weathering of volcanic ashes, has adsorbent ability for several mycotoxins. The present study was designed to study the effects of bentonite clay upon OTA-induced immunosuppression in broiler chicks. For this, 480 day-old broiler chicks were procured from a local hatchery and then different combinations of OTA (0.15, 0.3, or 1.0 mg/kg) and bentonite clay (5, 10, and 20 g/kg) were incorporated into their feed. At 13, 30, and 42 days of age, parameters such as antibody responses to sheep red blood cells, in situ lymphoproliferative responses to mitogen (PHA-P), and in situ phagocytic activity (i.e., via carbon clearance) were determined respectively. The results indicated there was a significant reduction of total antibody and immunoglobulin titres, lymphoproliferative responses, and phagocytic potential in OTA-treated birds, suggesting clear immunosuppression by OTA in birds in a dose-dependent manner. These results were also significantly lower in all combination groups (OTA with bentonite clay), suggesting few to no effects of feeding bentonite clay upon OTA- induced alterations in different immune parameters.     

Composite Nanoarchitectonics with Polythiophene,MWCNTs-G,CuO and Chitosan as a Voltammetric Sensor for Detection of Cd(II) Ions

Journal of Inorganic and Organometallic Polymers and Materials - In this study, we describe an electrochemical method for detecting Cd(II) ions, utilizing a glassy carbon electrode (GCE) modified...     

Self‐Assembly of Ferromagnetic Organic–Inorganic Perovskite‐Like Films

Perovskite‐based organic–inorganic hybrids hold great potential as active layers in electronics or optoelectronics or as components of biosensors. However, many of these applications require thin films grown with good control over structure and thickness—a major challenge that needs to be addressed. The work presented here is an effort towards this goal and concerns the layer‐by‐layer deposition at ambient conditions of ferromagnetic organic–inorganic hybrids consisting of alternating CuCl₄‐octahedra and organic layers. The Langmuir‐Blodgett technique used to assemble these structures provides intrinsic control over the molecular organization and film thickness down to the molecular level. Magnetic characterization reveals that the coercive field for these thin films is larger than that for solution‐grown layered bulk crystals. The strategy presented here suggests a promising cost effective route to facilitate the excellently controlled growth of sophisticated materials on a wide variety of substrates that have properties relevant for the high density storage media and spintronic devices.     

Simplified gateway selection scheme for multihop relay in vehicular ad hoc network

Integrating vehicular ad hoc network (VANET) and universal mobile telecommunication system (UMTS) could be a promising architecture for future machine‐to‐machine applications. This integration can help vehicles have steady Internet connection through the UMTS network and in communicating with other vehicles. However, dead spot areas and unsuccessful handoff processes caused by the high speed of vehicles can disrupt the implementation of this kind of architecture. In this paper, a new simplified gateway selection (SGS) scheme for multihop relay in a VANET‐UMTS integration network is proposed. The proposed scheme extends the coverage or/and calming of the frequent handoff process and allows vehicles to continue to be connected to the UMTS infrastructure network. An integrated simulation environment that combines VanetMobiSim and NS2 is used to simulate and evaluate the proposed scheme. The simulation results show that the SGS scheme performed better when it was implemented with ad hoc on a demand distance vector routing and destination‐sequenced distance vector routing protocols. Furthermore, the SGS scheme is compared with other cluster‐based gateway selections used in the previous works. The results show that our SGS scheme outperforms other cluster‐based gateway selections scheme in terms of selection delay, control packet overhead, packet delivery ratio, and overall throughput. Copyright © 2013 John Wiley & Sons, Ltd.     

Testing that a distribution is new better than used of age to

Hollander and Proschan (1972) gave a test of NBU-ness of a distribution F, but it was pointed out by Green and Tiwari (1989) that the test more appropriately related to much wider null and alternative hypotheses than those stated, and provided suitable critical values. Similarly, Hollander, Park and Proschan (1986) later provided a test that a distribution is NBU-t_o and a modified test was given by Ebrahimi and Habibullah (1990). However, a similar criticism may be levelled against these tests and a modified test is here provided for appropriate, more general, hypotheses.     

Revised test that a distribution is new better than used

The modified test of NBU-ness given by Green and Tiwari (1) related to more general null and alternative hypotheses than the corresponding test given by Hollander and Proschan (2). The Green and Tiwari test used an upper bound for the basic of the basic criterion, resulting in the test not being very powerful. In this revised test, suitable estimate of the variance is used instead of an upper bound. This is appropriate because a large sample size is assumed. The resulting test is more powerful than the earlier Green-Tiwari test, and more generally applicable than the Hollander-Proschan test.