Structural changes of glass-ceramics of the Cu2O-Al2O3-SiO2 system on heating in air

The behaviour of copper ions in low thermal expansion glass-ceramics prepared from Cu₂O · Al₂O₃ ·_nSiO₂ glasses, or in-spodumene type Cu₂O · Ae₂O₃ ·nSiO₂ crystals included in the glass-ceramics on heating in air was investigated. On hewing at 300 to 500° C, the copper ions behaved as in the corresponding glasses. Cuprous ions in the glass-ceramics or-spondumene type crystals were oxidized into the cupric state, and at the same time an equal amount of cuprous ions to those oxidized were expelled out of the specimen for the requirement of electrical charge neutrality and then reacted with oxygen to form CuO on the surface. The oxidation of cuprous ions and the decrease of the copper content of the-spondumene type crystals brought about a considerable decrease in the lattice spooings.     

MiR-10a in Pancreatic Juice as a Biomarker for Invasive Intraductal Papillary Mucinous Neoplasm by miRNA Sequencing

New biomarkers are needed to further stratify the risk of malignancy in intraductal papillary mucinous neoplasm (IPMN). Although microRNAs (miRNAs) are expected to be stable biomarkers, they can vary owing to a lack of definite internal controls. To identify universal biomarkers for invasive IPMN, we performed miRNA sequencing using tumor-normal paired samples. A total of 19 resected tissues and 13 pancreatic juice samples from 32 IPMN patients were analyzed for miRNA expression by next-generation sequencing with a two-step normalization of miRNA sequence data. The miRNAs involved in IPMN associated with invasive carcinoma were identified from this tissue analysis and further verified with the pancreatic juice samples. From the tumor-normal paired tissue analysis of the expression levels of 2792 miRNAs, 20 upregulated and 17 downregulated miRNAs were identified. In IPMN associated with invasive carcinoma (INV), miR-10a-5p and miR-221-3p were upregulated and miR-148a-3p was downregulated when compared with noninvasive IPMN. When these findings were further validated with pancreatic juice samples, miR-10a-5p was found to be elevated in INV (p = 0.002). Therefore, three differentially expressed miRNAs were identified in tissues with INV, and the expression of miR-10a-5p was also elevated in pancreatic juice samples with INV. MiR-10a-5p is a promising additional biomarker for invasive IPMN.     

Sintering of Confined Silica in Oxidized Silicon Particles

We observed electron-beam-induced sintering of amorphous silica in oxidized submicrometer silicon particles and analyzed the nature of mass transport in linear and triangular particle assemblies. The movement of silica around the rigid crystalline cores occurs rapidly and fills the necks, but the relative core positions in the sintered product depends on the initial geometry of the confined oxide. However, a thin layer of silica remains stable against the flow.     

Copper ⇌ Alkali Ion Exchange of Alkali Aluminosillcate Glasses in Copper-Containing Molten Salt: I, Monovalent Copper Salt, CuCl

Cu⁺⇌ R⁺ (R = Li, Na, and K) ion exchange experiments were conducted for 20R₂O·10Al₂O₃·70SiO₂ glasses in molten CuCl at 550°C in air and nitrogen atmospheres. The depth profiles of the copper incorporated into glasses were determined with an electron microprobe X-ray analyzer. The total amount of diffusing copper, M _t, strongly depended on the type of alkali ion in the glass and the ion-exchange atmosphere; i.e., M _t increased with increasing cationic size in the order Li < Na < K and M _t was greater in air than in nitrogen. The Cu ⇌ R⁺ ion exchange kinetics are discussed in detail.     

Variational Bayes solution of linear neural networks and its generalization performance

It is well known that in unidentifiable models, the Bayes estimation provides much better generalization performance than the maximum likelihood (ML) estimation. However, its accurate approximation by Markov chain Monte Carlo methods requires huge computational costs. As an alternative, a tractable approximation method, called the variational Bayes (VB) approach, has recently been proposed and has been attracting attention. Its advantage over the expectation maximization (EM) algorithm, often used for realizing the ML estimation, has been experimentally shown in many applications; nevertheless, it has not yet been theoretically shown. In this letter, through analysis of the simplest unidentifiable models, we theoretically show some properties of the VB approach. We first prove that in three-layer linear neural networks, the VB approach is asymptotically equivalent to a positive-part James-Stein type shrinkage estimation. Then we theoretically clarify its free energy, generalization error, and training error. Comparing them with those of the ML estimation and the Bayes estimation, we discuss the advantage of the VB approach. We also show that unlike in the Bayes estimation, the free energy and the generalization error are less simply related with each other and that in typical cases, the VB free energy well approximates the Bayes one, while the VB generalization error significantly differs from the Bayes one.     

A pilot survey of 39 Victorian WWTP effluents using a high speed luminescent umu test in conjunction with a novel GC-MS-database technique for automatic identification of micropollutants

In 2007, samples of treated effluent were collected at point of discharge to the environment from 39 wastewater treatment plants (WWTPs) located across Victoria, Australia grouped by treatment type. Sample genotoxicity was assessed with a high-throughput luminescent umu test method using Salmonella typhimurium TL210 strain, with and without addition of a commercially available metabolic activation system. Samples were also screened using a gas chromatographic-mass spectrometric mass-structure database recognition method. A genotoxic response was observed in half of the samples tested without metabolic activation system (相似文献   

High‐luminance 1‐m‐long plasma tubes for wall displays

Abstract— The plasma‐tube array is expected to realize a wall‐sized display. This method will realize an emissive‐type display with a flexible screen shape and an expandable screen size. The shape of the plasma tube was investigated to realize high luminance, high luminance efficacy, and high flexural strength. As the result, a cylindroid tube is proposed to satisfy these demands. An experimental display of 1 m × 128 mm has been developed with these cylindroid tubes and it demonstrated a high luminous efficacy of 3.1 lm/W.