Power-aware network swapping for wireless palmtop PCs

Virtual memory is considered to be an unlimited resource in desktop or notebook computers with high storage capabilities. However, in wireless mobile devices, like palmtops and personal digital assistants (PDAs), storage memory is limited or absent due to weight, size, and power constraints, so that swapping over remote memory devices can be considered as a viable alternative. However, power-hungry wireless network interface cards (WNICs) may limit the battery lifetime and application performance if not efficiently exploited. In this paper, we study performance and energy of network swapping in comparison with swapping on local microdrives and flash memories. We report the results of extensive experiments conducted on different WNICs and local swapping devices, using both synthetic and natural benchmarks. Our study points out that remote swapping over power-manageable WNICs can be more efficient than local swapping, especially in bursty workload conditions. Such conditions can be forced where possible by reshaping swapping requests to increase energy efficiency and performance.     

Designing for parallel fuzzy computing

As the number of fuzzy logic applications increases, demand for faster architectures will grow. Our design for a VLSI fuzzy processor uses fuzzy inference techniques that optimize processing time. Preprocessing that reduces the number of rules to be processed, parallel computation of active rule degrees of activation, and scalability are major features of this architecture. The journal issue contains a concise summary of this article. The complete article is linked to Micro's home page on the World Wide Web (http://www.computer.org/pubs/micro/micro.htm)     

The polymerase chain reaction detects B cell clonalities in patients with Sj?gren's syndrome and suspected malignant lymphoma

OBJECTIVE: To investigate the usefulness of the polymerase chain reaction (PCR) to detect B cell clonal expansions in tissues where lymphoproliferative disease was suspected in the course of Sj?gren's syndrome (SS). METHODS: Tissue samples from 7 patients with definite (5 cases) or probable (2 cases) SS were subjected to routine histopathologic studies, immunophenotyping, and genotypic analysis, including Southern blotting and PCR amplification of immunoglobulin heavy chain (IgH) variable-diversity-joining (VDJ) region gene rearrangements. RESULTS: Malignant lymphoma was detected in 3 cases, and myoepithelial sialadenitis in the remaining 4. B cell clonal expansion was detected in 7/7 cases by PCR, 5/7 by Southern blotting, and in no case of myoepithelial sialadenitis by kappa/lambda light chain immunophenotyping. CONCLUSION: PCR may represent a quick and powerful tool to detect B cell clonalities in SS. Such information may provide new insights into the pathogenesis of the disease and may improve the clinical approach to the patients.     

Role of anionic and nonionic surfactants on the control of particle size and latex colloidal stability in the seeded emulsion polymerization of butyl methacrylate

The evolution of the main colloidal parameters in the seeded starved‐feed semi‐continuous emulsion polymerization of butyl methacrylate (BMA) was investigated, with the main purpose of assessing the effectiveness of the semi‐empirical relationship S = K · S_S · ΔA/A_S as a tool to define the surfactant/monomer feed ratio (∝ K) best suited to achieve a target particle size. In particular, the effect of the type and amount of surfactant [i.e., anionic, sodium dodecyl sulfate (SDS), or nonionic, Brij 58P] added during the semi‐continuous stage was considered. Coagulum formation was never observed under the adopted experimental conditions. To detect the occurrence of secondary nucleation or particle aggregation, or both, the particle size and number of particles, the surface tension and the particle surface coverage ratio were correlated. The best results were obtained with SDS and 0.8 ≤ K ≤ 3. In fact, under the selected experimental conditions, only with SDS did the number of particles remain nearly constant throughout the polymerization at the value defined by the seed latex; the particle size distribution was highly monodisperse, and the final particle diameter closely matched the calculated one (～ 120 nm). The above semi‐empirical relationship based on the adjustable parameter K was validated by running test polymerizations aimed at lattices with well‐defined particle size. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 3083–3094, 2006     

Engineering of functional supramacromolecular complexes of proteins (enzymes) using reversed micelles as matrix microreactors

The size of the inner water cavity of reversed micelles formedin a triple system ‘water-surfactant-organic solvent’can be widely varied by changing the degree of surfactant hydration.This gives grounds to use reversed micelles as matrix microreactorsfor the design of supramolecular complexes of proteins. Usingultracentrifugation analysis, it has been demonstrated thatthe oligomeric composition of various enzymes (ketoglutaratedehydrogenase, alkaline phosphatase, lactic dehydrogenase, glyceraldehyde-3-phosphatedehydrogenase) solubilized in reversed micelles of Aerosol OT[sodium bis(2-ethylehexyl)sulfosuccinate] in octane changesupon variation of the degree of hydration. An oligomeric complexforms under conditions when the radius of the micelle innercavity is big enough to incorporate this complex as a whole.At lower degrees of hydration the micelles ‘uncouple’such complexes to their components. The catalytic propertiesof various oligomeric complexes have been studied. Possibilitiesof using reversed micelles for the separation of subunits ofoligomeric enzymes under non-denaturating conditions have beendemonstrated. In particular, the isolated subunits of alkalinephosphatase, lactic dehydrogenase and glyceralde-hyde-3-phosphatedehydrogenase have been found to be active in Aerosol OT reversedmicelles. The dependences of the catalytic activity of oligomericenzymes represent saw-like curves. The maxima of the catalyticactivity observed at these curves relate to the functioningof various oligomeric forms of an enzyme. The radii of the micelleinner cavity under conditions when these maxima are observedcorrelate with the linear dimensions of the enzyme oligomericforms. Correlation of the position of a maximum with the shapeof an oligomeric complex is discussed.     

Chemiotropic behavior of female olive fly (Bactrocera oleae GMEL.) onOlea europaea L

An interpretation is given of a number of observations on the chemiotropic behavior ofBactrocera oleae in connection with olive maceration water and the fly's return to the olive groves after the first summer rains. To this end, the headspace of both maceration water and leaf leaching water, simulating rainfall, were examined. In both cases, the presence of ammonia, which is generally known to attract fruit flies (Diptera, Tephritidae), was detected and, for the first time, in addition to other compounds that are inert for the fly, the presence of styrene was also detected. This aromatic hydrocarbon was found to be a strong attractant. It is shown that both ammonia and styrene are products of the metabolism of microbial flora present on the olive and leaf surface.     

Dynamic SLAs management in service oriented environments

The increasing adoption of service oriented architectures across different administrative domains, forces service providers to use effective mechanisms and strategies of resource management in order for them to be able to guarantee the quality levels their customers demands during service provisioning. Service level agreements (SLA) are the most common mechanism used to establish agreements on the quality of a service (QoS) between a service provider and a service consumer. The WS-Agreement specification, developed by the Open Grid Forum, is a Web Service protocol to establish agreements on the QoS level to be guaranteed in the provision of a service. The committed agreement cannot be modified during service provision and is effective until all activities pertaining to it are finished or until one of the signing party decides to terminate it. In B2B scenarios where several service providers are involved in the composition of a service, and each of them plays both the parts of provider and customer, several one-to-one SLAs need to be signed. In such a rigid context the global QoS of the final service can be strongly affected by any violation on each single SLA. In order to prevent such violations, SLAs need to adapt to any possible needs that might come up during service provision. In this work we focus on the WS-Agreement specification and propose to enhance the flexibility of its approach. We integrate new functionality to the protocol that enable the parties of a WS-Agreement to re-negotiate and modify its terms during the service provision, and show how a typical scenario of service composition can benefit from our proposal.     

Interfacing human and computer with wireless body area sensor networks: the WiMoCA solution

Wireless Body Area Sensor Networks (WBASN) are an emerging technology enabling the design of natural human–computer interfaces (HCI). Automatic recognition of human motion, gestures, and activities is studied in several contexts. For example, mobile computing technology is being considered as a replacement of traditional input systems. Moreover, body posture and activity monitoring can be used for entertainment and health-care applications. However, until now, little work has been done to develop flexible and efficient WBASN solutions suitable for a wide range of applications. Their requirements pose new challenges for sensor network designs, such as optimizing traditional solutions for use as environmental monitoring-like applications and developing on-the-field stress tests. In this paper, we demonstrate the flexibility of a custom-designed WBASN called WiMoCA with respect to a wide range of posture and activity recognition applications by means of practical implementation and on-the-field testing. Nodes of the network mounted on different parts of the human body exploit tri-axial accelerometers to detect its movements. The advanced digital Micro-electro-mechanical system (MEMS) based inertial sensor has been chosen for WiMoCA because it demonstrated high flexibility of use in many different situations, providing the chance to exploit both static and dynamic acceleration components for different purposes. Furthermore, the sensibility and accuracy of the sensing element is perfectly adequate for monitoring human movement, while keeping cost low and size compact, thus meeting our requirements. We implemented three types of applications, stressing the WBASN in many aspects. In fact, they are characterized by different requirements in terms of accuracy, timeliness, and computation distributed on sensing nodes. For each application, we describe its implementation, and we discuss results about performance and power consumption.

Human cytidine deaminase: a three-dimensional homology model of a tetrameric metallo-enzyme inferred from the crystal structure of a distantly related dimeric homologue

Cytidine deaminase (CDA) is a cytosolic metalloprotein whose functional unit can be either a homotetramer (T-CDA) or a homodimer (D-CDA), depending on the species. In 1994, the first crystal structure of the dimeric Escherichia coli CDA has been published. However, a crystal structure of a tetrameric CDA was not determined until 2002. Prior to the disclosure of the experimentally elucidated structure of a tetrameric CDA, we derived a homology model of the human T-CDA employing the crystal structure of the dimeric E. coli CDA as a template. The comparison of our theoretical model with the crystal structure of the human T-CDA, subsequently published in 2004, validates our prediction: not only of the structural features of the monomer and the details of the binding site, but also the multimeric arrangement of the subunits were determined with high accuracy in our model. By means of a phylogenetic analysis conducted on CDAs from various organisms, we demonstrate that the E. coli CDA is one of the furthest known homologues of the human enzyme. Nonetheless, despite the evolutionary distance and, more importantly, the different multimeric arrangement of their functional units, the E. coli CDA proved to have all the necessary information to accurately infer the structure of its human homologue.     

Increasing application accessibility through Java

Java has begun to open up new possibilities for accessing applications on the Web. With Java, developers can write applications as applets and insert them into Web pages. The user can then retrieve and execute them with local computing resources. We show how developers can use this feature to create a network computing platform that lets Web users share applications not specifically devised for network use, including those that are computationally intensive. With our approach, the network is not involved as long as the user executes operations on the graphical interface, which is executed locally on the client. Only when users require some computational response from the server do they need to access it. Access is straightforward; authorized users can access the application from any node connected with the Internet as long as they have a Java-enabled Web browser. We have used used one such network computing platform to port an existing tool and develop a new application