Hardware Implementation of a Fixed-Point Decoder for Low-Density Lattice Codes

Journal of Signal Processing Systems - This paper describes a field-programmable gate array (FPGA) implementation of a fixed-point low-density lattice code (LDLC) decoder where the Gaussian mixture...     

Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin

The crystal structure of transducin's betagamma subunits complexed with phosducin, which regulates Gtbetagamma activity, has been solved to 2.4 angstroms resolution. Phosducin has two domains that wrap around Gtbetagamma to form an extensive interface. The N-terminal domain binds loops on the "top" Gtbeta surface, overlapping the Gtalpha binding surface, explaining how phosducin blocks Gtbetagamma's interaction with Gtalpha. The C-terminal domain shows structural homology to thioredoxin and binds the outer strands of Gtbeta's seventh and first blades in a manner likely to disrupt Gtbetagamma's normal orientation relative to the membrane and receptor. Phosducin's Ser-73, which when phosphorylated inhibits phosducin's function, points away from Gtbetagamma, toward a large flexible loop. Thus phosphorylation is not likely to affect the interface directly, but rather indirectly through an induced conformational change.     

Attenuation of heavy metal toxicity of the activated sludge process by treatment with ferric chloride

Industrial wastes containing heavy metals can interfere with the normal operation of municipal wastewater treatment plants utilizing biological treatment processes. It is well known, however, that activated sludge can become acclimated to toxic levels of heavy metals if the dosages are increased gradually. Although such an acclimation procedure could prevent inhibitory effects of slug loads of toxins, the use of toxic heavy metals for normal plant operation is too perilous for consideration. It is, however, acceptable to utilize a nontoxic metal that may give general tolerance to toxic metals.

Laboratory experiments were conducted to examine the use of ferric chloride acclimation for treatment against heavy metal toxicity of an activated sludge process. The oxygen uptake of acclimated and unacclimated seed was measured by respirometry to determine the inhibitory effects of Ag and Pb.

The toxic effects of Ag and Pb were greatly reduced for acclimated seed. The experimental data area utilized in kinetic rate equations, and families of curves are developed to show the inhibition of Ag and Pb at a range of concentrations when the activated sludge is acclimatized at different concentrations of Fe(III).     

Soft-bit decoding of regular low-density parity-check codes

A novel representation, using soft-bit messages, of the belief propagation (BP) decoding algorithm for low-density parity-check codes is derived as an alternative to the log-likelihood-ratio (LLR)-based BP and min-sum decoding algorithms. A simple approximation is also presented. Simulation results demonstrate the functionality of the soft-bit decoding algorithm. Floating-point soft-bit and LLR BP decoding show equivalent performance; the approximation incurs 0.5-dB loss, comparable to min-sum performance loss over BP. Fixed-point results show similar performance to LLR BP decoding; the approximation converges to floating-point results with one less bit of precision.     

Assessment of biofilm destabilisation and consequent facilitated zinc transport.

In infiltration basins, such as in any kind of porous media, bacteria may form biofilms. When conditions induce destabilization of this biofilm, resulting colloids are transported by the hydraulic flow. Some studies have focused on the role played by these bacterial colloids in pollutants transport in soil. This study deals with the ability of Pseudomonas putida to retain zinc and investigates the facilitated transport of this metal. Batch and columns experiments have been carried out. Bacteria display a great affinity for zinc in batch experiments and facilitated transport have been highlighted in a small extent, for the moment. A scenario of stabilization/destabilization of the biofilm has been designed and may be employed for further investigations.     

Relative contribution of low-density lipoprotein receptor and lipoprotein lipase gene mutations to angiographically assessed coronary artery disease among French Canadians

A possible future clinical application of NMDA receptor antagonists is the control of the development of opiate analgesic tolerance. Therefore, the ability of NMDA receptor antagonists to modify the acute analgesic effects of opiates becomes increasingly important. The present study sought to evaluate the analgesic potency of combined administration of morphine (5-20 mg/kg) and a competitive NMDA receptor antagonist D-CPPene (SDZ EAA 494; 3-(2-carboxypiperazin-4-yl)-1-propenyl-1-phosphonic acid; 0.3-5.6 mg/kg) in the tail-flick and tail-pinch tests with rats. It was found that D-CPPene significantly increased the duration of morphine analgesia, but there was hardly any evidence for potentiation of morphine analgesia shortly after morphine administration. This effect could only in part be attributed to the D-CPPene-induced disruption of the development of 'learned hyperresponsiveness' (i.e., acquisition of decreased latencies to escape from repeated exposures to noxious stimulation). In addition, the plasma concentration of morphine was not affected by concurrent treatment with D-CPPene.     

Research issues in developing compact pulsed power for high peak power applications on mobile platforms

Pulsed power is a technology that is suited to drive electrical loads requiring very large power pulses in short bursts (high-peak power). Certain applications require technology that can be deployed in small spaces under stressful environments, e.g., on a ship, vehicle, or aircraft. In 2001, the U.S. Department of Defense (DoD) launched a long-range (five-year) Multidisciplinary University Research Initiative (MURI) to study fundamental issues for compact pulsed power. This research program is endeavoring to: 1) introduce new materials for use in pulsed power systems; 2) examine alternative topologies for compact pulse generation; 3) study pulsed power switches, including pseudospark switches; and 4) investigate the basic physics related to the generation of pulsed power, such as the behavior of liquid dielectrics under intense electric field conditions. Furthermore, the integration of all of these building blocks is impacted by system architecture (how things are put together). This paper reviews the advances put forth to date by the researchers in this program and will assess the potential impact for future development of compact pulsed power systems.     

Clockless Stochastic Decoding of Low-Density Parity-Check Codes: Architecture and Simulation Model

This paper introduces clockless stochastic decoding for high-throughput low-density parity-check (LDPC) decoders. Stochastic computation provides ultra-low-complexity hardware using simple logic gates. Clockless decoding eliminates global clocking, which eases the worst-case timing restrictions of synchronous stochastic decoders. The lack of synchronization might use outdated bits to update outputs in computation nodes; however, it does not significantly affect output probabilities. A timing model of clockless-computation behaviours under a 90 nm CMOS technology is used to simulate the BER performance of the proposed decoding scheme. Based on our models, the proposed decoding scheme significantly reduces error floors due to the “lock-up” problem and achieves superior BER performance compared with conventional synchronous stochastic decoders. The timing model includes metastability to verify the affect on BER performance.     

Effects of transverse doping variations on the transient responseof silicon avalanche shaper devices

Two-dimensional (2-D) drift-diffusion simulations were performed to study the transient response of silicon avalanche shaper (SAS) devices that are used in high-power switching and pulse sharpening applications. The role of transverse doping variations on the transient device response has been studied. Our results clearly reveal a potential for filamentary current conduction. The filamentation, however, is shown to be strongly dependent on the transverse doping characteristics, and hence in principle, could he tailored