Hemoptysis caused by pulmonary arterial aneurysm, disclosing Beh?et disease. Apropos of 2 cases]

MCF7 and ZR75-1 breast cancer cells grow as adherent monolayers in tissue culture. Treatment with the serum serine protease plasmin causes them to detach and to grow as floating multicellular spheroids. Two plasmin activators, urokinase plasminogen activator and streptokinase, induce the same growth pattern changes in the presence of plasminogen. Serum contains also plasminogen activator inhibitors. Aged serum, deficient in plasminogen activator inhibitors, converts spontaneously monolayer breast cancer cells into multicellular spheroids which readily revert to monolayer growth after addition of fresh serum. Urokinase blocks the reversion. The formation of multicellular spheroids does not affect the proliferative rate of breast tumor cells but endows tumor cells with increased resistance to the chemotherapeutic drugs, doxorubicin and paclitaxel.     

Analytic computation of the photocurrent density in a n-6H-SiC/p-Si/n-Si/p-Si0.8Ge0.2 multilayer solar cell

In this work we conceived a model of a multilayer solar cell composed by four layers of opposite conductivities: an n-type 6H-SiC used as a frontal layer to absorb high energy photons (energy gap equals 2.9 eV), a p-type Si layer, an n-type Si layer and a p-type SiGe back layer to absorb low energy photons (Si_0.8Ge_0.2 with an energy gap equal to 0.8 eV). The impurity concentration in every layer of the model is taken equal to 10¹⁷ cm⁻³ to ensure abrupt junctions inside the cell. The optical properties of the separate layers have been fitted and tabulated to be used for thin films devices numerical simulation. We developed the equations giving the minority carrier concentration and the photocurrent density in each abscissa of the model. We used Matlab software to simulate and optimize the layers thicknesses to achieve the maximum photocurrent generated under AM0 solar spectrum. The results of simulation showed that the optimized structure could deliver, assuming 10⁵ cm/s surface recombination velocity, a photocurrent density of more than 53 mA/cm², which represents 88.3% of the ideal photocurrent (59.99 mA/cm²) that can be generated under AM0 solar spectrum.     

Adaptive type-2 fuzzy sliding mode controller for SISO nonlinear systems subject to actuator faults

In this paper, an adaptive type-2 fuzzy sliding mode control to tolerate actuator faults of unknown nonlinear systems with external disturbances is presented. Based on a redundant actuation structure, a novel type-2 adaptive fuzzy fault tolerant control scheme is proposed using sliding mode control. Two adaptive type-2 fuzzy logic systems are used to approximate the unknown functions, whose adaptation laws are deduced from the stability analysis. The proposed approach allows to ensure good tracking performance despite the presence of actuator failures and external disturbances, as illustrated through a simulation example.     

Adaptive fuzzy sliding mode power system stabilizer using Nussbaum gain

Power system stability is enhanced through a novel stabilizer developed around an adaptive fuzzy sliding mode approach which applies the Nussbaum gain to a nonlinear model of a single-machine infinite-bus （SMIB） and multi-machine power system stabilizer subjected to a three phase fault. The Nussbaum gain is used to avoid the positive sign constraint and the problem of controllability of the system. A comparative simulation study is presented to evaluate the achieved performance.     

Optimal Packet Loss Protection of Progressively Compressed 3-D Meshes

We consider a state-of-the-art system that uses layered source coding and forward error correction with Reed-Solomon codes to efficiently transmit 3-D meshes over lossy packet networks. Given a transmission bit budget, the performance of this system can be optimized by determining how many layers should be sent, how each layer should be packetized, and how many parity bits should be allocated to each layer such that the expected distortion at the receiver is minimum. The previous solution for this optimization problem uses exhaustive search, which is not feasible when the transmission bit budget is large. We propose instead an exact algorithm that solves this optimization problem in linear time and space. We illustrate the advantages of our approach by providing experimental results for the compressed progressive meshes (CPM) mesh compression technique.     

A meta-heuristic approach to solve a JIT scheduling problem in hybrid flow shop

In this paper we address a hybrid flow shop scheduling problem considering the minimization of the sum of the total earliness and tardiness penalties. This problem is proven to be NP-hard, and consequently the development of heuristic and meta-heuristic approaches to solve it is well justified. So, we propose an ant colony optimization method to deal with this problem. Our proposed method has several features, including some heuristics that specifically take into account both earliness and tardiness penalties to compute the heuristic information values. The performance of our algorithm is tested by numerical experiments on a large number of randomly generated problems. A comparison with solutions performance obtained by some constructive heuristics is presented. The results show that the proposed approach performs well for this problem.     

State observer based robust adaptive fuzzy controller for nonlinear uncertain and perturbed systems

A robust adaptive fuzzy controller, based on a state observer, for a nonlinear uncertain and perturbed system is presented. The state observer is introduced to resolve the problem of the unavailability of the state variables. Two control signals are added to a basic state feedback control law, deduced from a nominal model, to guarantee the tracking performance in the presence of structural uncertainties and external disturbances. The first control signal is computed from an adaptive fuzzy system and eliminates the effect of structural uncertainties and estimation errors. Updating the adjustable parameters is ensured by a PID law to obtain a fast convergence. Robustness of the closed-loop system is guaranteed by an H infinity supervisor computed from a Riccati type equation. Simulation example is presented to show the efficiency of the proposed method.     

Synthesis and characterization of radiation cross-linked PVP hydrogels and investigation of its potential as an antileishmanial drug carrier

Polymer Bulletin - The aim of this study was to elaborate a suitable hydrogel to be used as drug carrier for antileishmanial treatment. Therefore, a PVP hydrogel was synthesized using gamma...     

Efficient Rate-Distortion Optimized Media Streaming for Tree-Structured Packet Dependencies

When streaming packetized media data over a lossy packet network, it is desirable to use transmission strategies that minimize the expected distortion subject to a constraint on the expected transmission rate. Because the computation of such optimal strategies is usually an intractable problem, fast heuristic techniques are often used. We first show that when the graph that gives the decoding dependencies between the data packets is reducible to a tree, optimal transmission strategies can be efficiently computed with dynamic programming algorithms. The proposed algorithms are much faster than other exact algorithms developed for arbitrary dependency graphs. They are slower than previous heuristic techniques but can provide much better solutions. We also show how to apply our algorithms to find high-quality approximate solutions when the dependency graph is not tree reducible. To validate our approach, we run simulations for MPEG1 and H.264 video data. We first consider a simulated packet erasure channel. Then we implement a real video streaming system and provide experimental results for an Internet connection.     

Electron Charge Density Distribution from X-ray Diffraction Study of the M-Nitrophenol Compound in the Monoclinic Form

At room temperature, the m-Nitrophenol (m-NPH) appears in two polymorphic structures: orthorhombic and monoclinic forms. In the present work, we shall focus on the monoclinic form of this compound which has a centrosymmetric structure with the space group P2₁/n. The molecular dipole moment has been estimated experimentally. High resolution single crystal diffraction experiment was performed at low temperature with MoKα radiation. The crystal structure was refined using the multipolar model of Hansen and Coppens (1978). The molecular electron charge density distribution is described accurately. The study reveals the nature of inter-molecular interactions including charge transfer and hydrogen bonds. In this crystal, hydrogen bonds of moderate strength occur between the hydroxyl group and the O atom in the nitro one.