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1.
We investigated the effect of repeated cold stress (RCS) on the capsaicin-evoked release of glutamate from the primary afferent fibers of the rat, and compared this with the effect of inoculation of complete Freund's adjuvant (adjuvant inoculation). The release of glutamate was measured using a fluorometric on-line continuous monitoring system in which the immobilized glutamate dehydrogenase column was connected to an in vitro superfusion system. In the presence of 0.3 microM tetrodotoxin, the application of 1 microM capsaicin to spinal dorsal horn slices evoked glutamate release (18.6 +/- 1.2 pmol mg(-1) protein, n = 11). In rats subjected to RCS (RCS rats), the release of glutamate evoked by 1 microM capsaicin was markedly increased to 272% (n = 6, P < 0.05) of the value for the control group, although the basal release was not significantly altered (n = 6, P > 0.05). Adjuvant inoculation produced a significant increase in the basal and capsaicin (1 microM) evoked release of glutamate to 141 and 344% (n = 6, P < 0.05) of the value for the control group, respectively. The present results suggest that the facilitated release of glutamate from capsaicin-sensitive primary afferent terminals in the spinal dorsal horn is, at least in part, involved in the hyperalgesia of RCS rats as well as the complete Freund's adjuvant-induced hyperalgesia. 相似文献
2.
DeepakSharma VishalSHarma 《今日电子》2003,(9):61-63
面对电信业的低迷,运营商和设备制造商都捏紧了钱袋,想方设法少花钱多办事。这就意味着,必须改进现有传输网(见图1),使话音和数据传输效率更高。从网络部署的角度来看,运营商需要:用一些有效的方法,将多协议数据转换到SONET/SDH信道上;用一种灵活的带宽适应机制,使SONET/SDH信道大小与在其中传输的数据的需求相一致;用一种机制,灵活并以理想的动态方式改变整个SONET/SDH网络的信道带宽。这就要求集成电路供应商提供有助于在SONET/SDH上有效传输数据的芯片。虽然现在有多种SONET/SDH信息包(PoS)产品,但是它们的转换效率都太… 相似文献
3.
A method for evaluating the accuracy of a device model and its tendency toward convergence problems before implementing it as a SPICE primitive is presented. Two different GaAs MESFET models suitable for analyzing nonlinear analog and microwave circuits are implemented using generic SPICE primitives. It is shown that no modification to the SPICE program is required. Controlled sources are extensively used in implementing the models using this method 相似文献
4.
Hari B. Goyal M. O. Garg K. R. Rao R. D. Srivastava 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》1985,35(2):49-56
The kinetics of the reaction of acetic acid and acetylene over zinc acetate-activated carbon catalyst was investigated over a wide range of process variables in a pilot reactor. Although various catalytic reaction mechanisms were postulated, the rate of reaction was most satisfactorily correlated by a mechanism of surface reaction between charged adsorbed acetic acid and acetylene, which assumes that the rate controlling step was the irreversible charged adsorption of acetylene and acetic acid. 相似文献
5.
As system clock rates race to 100 MHz and beyond, designers of printed-circuit boards and multichip modules must watch out for such high-speed effects as ground bounce, ringing, reflections, and crosstalk. The author describes how today's high-speed printed-circuit boards and multichip modules require integrated design systems that include signal integrity analysis tools 相似文献
6.
A. Goyal E. D. Specht Z. L. Wang D. M. Kroeger J. A. Sutliff J. E. Tkaczyk J. A. Deluca L. Masur G. N. Riley 《Journal of Electronic Materials》1994,23(11):1191-1197
Microstructural origins for reduced weak-link behavior in high-Jc melt-processed YBCO, spray pyrolyzed thick films of Tl-1223, metallic precursor Y-124 polycrystalline powder-in-tube (PIT)
wires and PIT Bi-2212/2223 are discussed. Since the materials studied are the highest Jc, polycrystalline, high-Tc superconductors fabricated worldwide, the results provide important guidelines for further improvements in superconducting
properties, thereby enabling practical applications of these materials. It is found that strongly linked current flow within
domains of melt-processed 123 occurs effectively through a single crystal path. In c-axis oriented, polycrystalline Tl-1223
thick films, local in-plane texture has been found to play a crucial role in the reduced weak-link behavior. Formation of
“colonies” of grains with a common c-axis and modest in-plane misorientation was observed. Furthermore, a colony boundary
in general has a varying misorientation along the boundary. Large regions comprised primarily of low angle boundaries were
observed. Percolative transport through a network of such small angle boundaries appears to provide the nonweak-linked current
path. Although powder-in-tube BSCCO 2212 and 2223 also appear to have a “colony” microstructure, there are some important
differences. Colonies in BSCCO consist of stacks of grains with similar c-axis orientation in contrast to colonies in Tl-1223
films where few grains are stacked on top of one another. Furthermore, most grains within a colony in BSCCO have the same
lateral dimensions as that of the colony, resulting largely largely in “twist” boundaries. Further microstructural characterization
of high-Jc PIT 2212 and 2223 is currently underway. In the case of Y-124 wires, weak macroscopic in-plane texture is found. Additional
measurements are underway to determine if a sharper, local in-plane texture also exists. It is found that in three of the
four types of superconductors studied, reduced weak-link behavior can be ascribed to some degree of biaxial alignment between
grains, either on a “local” or a “global” scale. 相似文献
7.
D. M. Kroeger Ph.D. A. Goyal Ph.D. 《JOM Journal of the Minerals, Metals and Materials Society》1992,44(10):42-47
Critical current density (Jc) in the presence of a magnetic field is the property that currently limits many applications of the high-critical-temperature oxide superconductors. Poor current transmission at grain boundaries and weak flux pinning are responsible for the low critical current densities observed in bulk materials. Since 1986, substantial progress has been made both in understanding the microstructural factors affecting Jc and in developing practical fabrication methods. Much of the fundamental understanding has been obtained from studies of YBa2Cu3O7?x while the bismuth and thallium-based compounds appear to offer greater potential as the basis for the first practical conductors. 相似文献
8.
Copolymers of 2-hydroxy ethyl methacrylate-2-vinyl pyridine (H/V) of different composition were synthesized by free radical bulk polymerization using azobisisobutyronitrile (AIBN) as an initiator under nitrogen atmosphere. The copolymer compositions were calculated from 1H NMR spectra. The reactivity ratios for H/V copolymers obtained from a linear Kelen-Tudos method (KT) and nonlinear error-in-variables method (EVM) are rH = 0.50 ± 0.10, rV = 1.04 ± 0.08 and rH = 0.55, rV = 1.06 respectively. The complete spectral assignment of methine, methylene, methyl, carbonyl, and aromatic carbon regions in term of compositional and configurational sequences of H/V copolymers were done with the help of 13C{1H} NMR, distortionless enhancement by polarization transfer (DEPT), two-dimensional heteronuclear single quantum coherence (HSQC) along with total correlated spectroscopy (TOCSY). © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 相似文献
9.
We propose an image hashing paradigm using visually significant feature points. The feature points should be largely invariant under perceptually insignificant distortions. To satisfy this, we propose an iterative feature detector to extract significant geometry preserving feature points. We apply probabilistic quantization on the derived features to introduce randomness, which, in turn, reduces vulnerability to adversarial attacks. The proposed hash algorithm withstands standard benchmark (e.g., Stirmark) attacks, including compression, geometric distortions of scaling and small-angle rotation, and common signal-processing operations. Content changing (malicious) manipulations of image data are also accurately detected. Detailed statistical analysis in the form of receiver operating characteristic (ROC) curves is presented and reveals the success of the proposed scheme in achieving perceptual robustness while avoiding misclassification. 相似文献
10.
T Tokano F Pelosi M Flemming L Horwood JJ Souza A Zivin BP Knight R Goyal KC Man F Morady SA Strickberger 《Canadian Metallurgical Quarterly》1998,9(9):916-920
INTRODUCTION: Defibrillation energy requirements in patients with nonthoracotomy defibrillators may increase within several months after implantation. However, the stability of the defibrillation energy requirement beyond 1 year has not been reported. The purpose of this study was to characterize the defibrillation energy requirement during 2 years of clinical follow-up. METHODS AND RESULTS: Thirty-one consecutive patients with a biphasic nonthoracotomy defibrillation system underwent defibrillation energy requirement testing using a step-down technique (20, 15, 12, 10, 8, 6, 5, 4, 3, 2, and 1 J) during defibrillator implantation, and then 24 hours, 2 months, 1 year, and 2 years after implantation. The mean defibrillation energy requirement during these evaluations was 10.9+/-5.5 J, 12.3+/-7.3 J, 11.7+/-5.6 J, 10.2+/-4.0 J, and 11.7+/-7.4 J, respectively (P = 0.4). The defibrillation energy requirement was noted to have increased by 10 J or more after 2 years of follow-up in five patients. In one of these patients, the defibrillation energy requirement was no longer associated with an adequate safety margin, necessitating revision of the defibrillation system. There were no identifiable clinical characteristics that distinguished patients who did and did not develop a 10-J or more increase in the defibrillation energy requirement. CONCLUSION: The mean defibrillation energy requirement does not change significantly after 2 years of biphasic nonthoracotomy defibrillator system implantation. However, approximately 15% of patients develop a 10-J or greater elevation in the defibrillation energy requirement, and 3% may require a defibrillation system revision. Therefore, a yearly evaluation of the defibrillation energy requirement may be appropriate. 相似文献