五轴铣削加工中心坐标转换数学模型的建立及应用

首先以 HERMLE C1200 U 为例分析了五轴铣削加工中心的基本结构,然后据此给出了涉及多轴铣削加工中心后置处理角度分配和坐标变换的数学模型,最后介绍了以此数学模型为核心,为UG 软件开发的后置处理软件 UG-HERP1.0的解决方案。     

Interaction of Yttria with Uranium Fluoride Gases (UFn, n= 4, 6) at High Temperatures

The corrosion mechanism and microstructural characteristics of yttria (Y₂O₃) exposed to uranium hexafluoride (UF₄) and uranium tetrafluoride gases at temperatures above 900°C were investigated. Processed yttria samples were exposed for times ranging from 5 to 40 min. A weight increase was observed after each test exposure. An outer corrosion scale composed of UO₂ and YF₃, and an inner corrosion layer of YF₃, were observed following the UF₆ reaction at nearly 1200 K. During the UF₄ exposure, an outer layer containing a liquid mixture of fluoride, oxygen, yttrium, uranium compounds, a secondary reaction layer of UO₂ followed by an inner layer composed of a solution of Y₂O₃ and YF₃, possibly in the form of YOF inner layer, were observed. It was found that the corrosion process is controlled by the diffusion which is evidenced by the parabolic growth rate of the secondary layer. After completion of the solidification process, the formation of a eutectic region and dendrites were observed throughout the outer scale. In general, at temperatures above 1173 K, high corrosion rates were observed, and yttria did not appear to be a viable containment material for UF₄ and UF₆.     

Investigation of Ant System parameter interactions by using design of experiments for job-shop scheduling problems

In recent years, one of the most important and promising research fields has been metaheuristics to find optimal or near-optimal solutions for NP-hard combinatorial optimization problems. Improving the quality of the solution or the solution time is basic research area on metaheuristics. Modifications of the existing ones or creation of hybrid approaches are the focus of these efforts. Another area of improving the solution quality of metaheuristics is finding the optimal combination of algorithm control parameters. This is usually done by design of experiments or one-at-a-time approach in genetic algorithms, simulated annealing and similar metaheuristics. We observe that, in studies which use Ant Colonies Optimization (ACO) as an optimization technique; the levels of control parameters are determined by some non-systematic initial experiments and the interactions of the parameters are not studied yet.In this study, the parameters of Ant System have been investigated on different sized and randomly generated job-shop scheduling problems by using design of experiments. The effects and interactions of the parameters have been interpreted with the outputs of the experiments. Referring to the statistical analysis it is observed that none of the interactions between the Ant System parameters has a significant effect on makespan value. A specific fractional experimental design is suggested instead of the full factorial design. Depending on the findings from the benchmark problems it will be a reliable approach to use the suggested design for saving time and effort in experiments without sacrificing the solution quality.     

Partial correlation with copula modeling

We propose a new partial correlation approach using Gaussian copula. Our empirical study found that the Gaussian copula partial correlation has the same value as that which is obtained by performing a Pearson’s partial correlation. With the proposed method, based on canonical vine and d-vine, we captured direct interactions among eight histone genes.     

一株丝状真菌发酵法产红色素培养基的研究

研究了一株丝状真菌Miug-2．7发酵法生产红色素的液体培养基最佳组分，以及液体发酵培养基最佳配方．结果表明，本试验范围内最佳质量配比是淀粉3％，蛋白胨1．0％，诱导物1％，起始pH7．5．     

基于快速原型制造技术的产品开发

介绍了适应市场的快速响应设计技术的内容，关键技术和具体实施策略，快速响应设计在企业竞争中的作用．同时说明了快速原型制造技术在快速制造中的作用．     

TiO_2系薄膜型氧敏材料的研究与发展综述

介绍了TiO2薄膜型氧敏材料的特性、氧敏机理及发展优势。就TiO2薄膜型氧敏材料的制备新方法和几种新型TiO2系薄膜以及相应的氧敏性能等重要方面进行了探讨,并对今后的研究与发展方向提出几点建议。     

Activatable Photosensitizers: Agents for Selective Photodynamic Therapy

Recent developments in the design of bifunctional and activatable photosensitizers rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While systematic studies have uncovered new dyes that can serve as potential photosensitizers, the most promising results have come from studies aimed at gaining precise control over the location and rate of cytotoxic singlet oxygen generation. As a consequence, higher selectivities and efficiencies in photodynamic treatment protocols are now within reach. This feature article highlights the variety of approaches that have been pursued to improve photodynamic therapy and to transform simple photosensitizers into smarter theranostic agents.     

DNA-directed immobilization of horseradish peroxidase onto porous SiO2optical transducers

ABSTRACT: Multifunctional porous Si nanostructure is designed to optically monitor enzymatic activity of Horseradish Peroxidase. First, an oxidized PSi optical nanostructure, a Fabry-Perot thin film, is synthesized and is used as the optical transducer element. Immobilization of the enzyme onto the nanostructure is performed through DNA-Directed Immobilization. Preliminary studies demonstrate high enzymatic activity levels of the immobilized Horseradish Peroxidase, while maintaining its specificity. The catalytic activity of the enzymes immobilized within the porous nanostructure is monitored in real time by reflective interferometric Fourier transform spectroscopy. We show that we can easily regenerate the surface for consecutive biosensing analysis by mild de-hybridization conditions.     

Chemical and microbiological status and volatile profiles of mouldy Civil cheese,a Turkish mould‐ripened variety

The objective of this study is to characterise the gross chemical and microbiological status and identify the volatile compounds of mouldy Civil cheeses. A total of forty‐one samples were surveyed, and gross compositional status of the cheeses was (as mean values): 6.5 for pH, 6.2% for fat‐in‐dry matter, 51.8% for moisture and 15.3% for water‐soluble nitrogen (as% of total nitrogen). Chemical composition of the cheese samples varied widely. Mouldy Civil cheese has similar pH values and moisture contents when compared with blue‐type cheeses, but it has distinct feature for fat contents. The microbiological counts of the samples were found to be high and some samples contained coliform bacteria. A total of 95 volatiles, including esters (28), acids (6), ketones (12), aldehydes (3), alcohols (15), terpenes (10), sulphur compounds (3) and miscellaneous (18), were identified in the volatile fractions of the cheeses, and principal volatile groups were esters, alcohols and ketones.