Zur numerischen Simulation von Wärmenetzen

Forschung im Ingenieurwesen - Der Aufsatz beschreibt eine Möglichkeit, beliebig vermaschte Wärmenetze numerisch zu simulieren. Basierend auf einer graphentheoretischen Beschreibung der...     

International orientation,efficiency of and regard for research in East and West Germany: A bibliometric investigation of aspects of technology genesis in the United Germany

The efficiency of areas of science was evaluated using the DEA method. Areas achieving a maximum orientation or regard of international publication are rated as efficient. The areas of reproductive medicine, organic and inorganic chemistry in the former Federal Republic can thus be regarded as efficient areas of science. No area of scientific research in the former East Germany was able to achieve the optimum. The determinant in this connection is the adverse situation with respect to international orientation whilst no substantial difference in regard for further research could be detected between East and West German research.     

Accumulation of nitrite and sulfite in yeast cells and synergistic depletion of the intracellular ATP content

Summary When nitrite or sulfite are applied to yeast cells below pH 5.0, an enormous intracellular accumulation occurs. It is assumed that nitrite and sulfite penetrate the cell membrane in their undissociated forms as nitrous acid (pK = 3.3) or sulfurous acid (pK =1.8), respectively. Due to the neutral intracellular pH they are trapped inside the cell in their anionic forms, which are impermeable to the cell membrane. It has previously been shown that sulfite causes a rapid depletion of the ATP content of yeast cells [Schimz, K. L. and Holzer, H. (1979) resp. Hinze et al. as above]. Similarly, millimolar concentrations of nitrite decrease the ATP level to less than 10% of the initial value. Nitrite and sulfite in combination deplete the ATP content of yeast cells much stronger than expected for the sum of the separate effects of these compounds (synergistic effect).

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Akkumulation von Nitrit und Sulfit in Hefezellen und synergistischer Abfall des intrazellulären ATP-Gehalts

Zusammenfassung Wenn Hefezellen mit Nitrit oder Sulft bei pH-Werten unter 5,0 inkubiert werden, beobachtet man eine starke intracelluläre Akkumulation von Nitrit, bzw. Sulfit. Es ist anzunehmen, daß Nitrit und Sulfit in ihrer undissoziierten Form als salpetrige Säure (pK=3,3) bzw. schweflige Säure (pK=1,8) penetrieren und dann in den Zellen durch Neutralisation zu den anionischen Formen, die die Zellmembran nicht mehr permeieren können, abgefangen werden. Ähnlich dem früher beschriebenen raschen Abfall des ATP-Gehaltes nach Zusatz von Sulfit in Hefe [Schimz, KL und Holzer H (1979) Arch Microbiol 121:225–229] und in Bakterien [Hinze H, Maier K, Holzer H (1981) Z Lebensm Unters Forsch 172:389-392] verursacht auch Nitrit einen raschen Abfall des ATP-Gehaltes in Hefe auf weniger als 10 % des Anfangswertes. Werden Nitrit und Sulfit in Kombination verabreicht, so beobachtet man einen wesentlich stärkeren Abfall des ATP-Gehaltes als er aus der Summe der Einzeleffekte von Nitrit, bzw. Sulfit zu erwarten wäre (Synergistischer Effekt).

     

Nested multigrid methods for time-periodic,parabolic optimal control problems

We present a nested multigrid method to optimize time-periodic, parabolic, partial differential equations (PDE). We consider a quadratic tracking objective with a linear parabolic PDE constraint. The first order optimality conditions, given by a coupled system of boundary value problems can be rewritten as an Fredholm integral equation of the second kind, which is solved by a multigrid of the second kind. The evaluation of the integral operator consists of solving sequentially a boundary value problem for respectively the state and the adjoints. Both problems are solved efficiently by a time-periodic space-time multigrid method.     

The Nature of Struck-by Accidents

Construction accidents are broadly categorized into five basic groups, namely falls (from elevation), shock (electrical), caught in/between, struck-by, and other. “Struck-by” accidents accounted for 22% of all construction-related fatalities recorded by the Occupational Safety and Health Administration between 1985 and 1989. Recent (1997 to 2000) data show that the percentage of struck-by accidents constituted 24.6% of the fatalities and serious construction worker injuries. Struck-by accidents primarily involve workers struck by equipment, private vehicles, falling materials, vertically hoisted materials, horizontally transported materials, and trench cave ins. Determining possible causation factors of these accident types is often difficult, due to the broad categories utilized in the accident coding system. This study resulted in gaining insights about the root causes of the struck-by injuries. By finding the root causes, effective methods for accident prevention can be developed.     

Use of Trench Boxes for Worker Protection

Work in trenches can be very dangerous if workers are not provided with adequate protection against trench cave-ins. One method of providing for worker protection in trenches is with the use of trench boxes, widely used, engineered structures that permit workers to work safely in trenches. A study of the experiences of utility contractors with the use of trench boxes provided several notable findings that can help in implementing safe work practices in trenches. Most safety problems with the use of trench boxes are attributed to human error or judgment. For example, several respondents commented that workers were observed exiting from the trench boxes by walking up the backfill, a practice that exposes workers to the dangers of trench cave-ins. The importance of training was also evident in the results. Firms with better safety performance records conducted specialized training courses for their employees, and they provided more frequent training courses.     

Production of vertical nanowire resonators by cryogenic-ICP–DRIE

Silicon resonant sensors with large surface area-to-volume ratios provide high weighing sensitivity. This fact implies the possibility for detection of slight mass changes [i.e. by attached nanoparticles (NPs)]. Vertical silicon nanowire (SiNW) resonators are therefore suitable for exposure assessment or airborne NPs. SiNW arrays are top-down fabricated by nanolithography and subsequent inductively coupled plasma reactive ion etching at cryogenic temperature. Nanolithography is performed by conventional UV-lithography and nanoimprint for even smaller structures. Wire diameters are further reduced by multiple thermal oxidations and oxide stripping at times. Parameter effects of cryogenic dry etching are studied for SiNW arrays.     

Effect of a variety of organic additives on retention and efficiency in micellar liquid chromatography

The effect of 21 organic additives (alkanols, alkane diols, dipolar aprotic solvents, alkanes) on the chromatographic behavior (retention, elution strength, efficiency) of probe solutes of widely differing hydrophobicity, such as benzene and 2-ethylanthraquinone, have been examined using a C18 stationary phase and sodium dodecyl sulfate (SDS) micellar mobile phases. The mobile-phase elution strength parallels the octanol-water partition coefficients of the additives or their ability to bind to the SDS micellar system, due to the increased solubility in the mobile phase and reduced affinity for the additive-modified surfactant-coated stationary phase. The comparison of the elution strength of micellar mobile phases with that of a reference acetonitrile-water system indicates that the elution strength is lower for micellar systems and depends on the nature of the eluted solute. The displacement of the solute-micelle and solute-stationary phase binding equilibria is quantified for several probe solutes eluted with micellar mobile phases in the presence of 1-propanol, 1-butanol, 1-pentanol, and acetonitrile. A correlation was also observed between the number of theoretical plates and the hydrophobicity of the alcohol additives: the efficiency initially increased steeply and reached a plateau. Compared to benzene, a more hydrophobic additive was needed to attain the maximum efficiency for the more hydrophobic 2-ethylanthraquinone analyte. Dipolar aprotic solvents appear to be somewhat more effective in enhancing the efficiency than alcohols. The results are rationalized in terms of the ability of the organic additives to alter the composition, structure, dynamics, and properties of the micelles and the surfactant-coated stationary phase.     

A fully automatic peak-search program for the evaluation of Gauss-shaped diffraction patterns

Diffraction patterns (X-rays or neutrons) often contain regions of overlapping, unresolved peaks. When using energy-dispersive techniques with solid state detectors the degree of overlap is especially high because of the poor resolution of such detectors. Profile analysis then offers the possibility to overcome, or at least reduce this drawback. In this paper a peak-search program is represented for fully automatic separation of the individual peaks. Only the instrumental parameter fwhm (full width at half-maximum) and the recorded spectrum are required as input for the program. Results are given for orthorhombic MnSO₄.