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排序方式: 共有766条查询结果,搜索用时 15 毫秒
1.
Alawiya Reslan Juliano G. Haddad Liadrine Moukendza Koundi Philippe Desprs Jean-Loup Bascands Gilles Gadea 《International journal of molecular sciences》2021,22(5)
Mosquito-borne Zika virus (ZIKV) became a real threat to human health due to the lack of vaccine and effective antiviral treatment. The virus has recently been responsible for a global outbreak leading to millions of infected cases. ZIKV complications were highlighted in adults with Guillain–Barré syndrome and in newborns with increasing numbers of congenital disorders ranging from mild developmental delays to fatal conditions. The ability of ZIKV to establish a long-term infection in diverse organs including the kidneys has been recently documented but the consequences of such a viral infection are still debated. Our study aimed to determine whether the efficiency of ZIKV growth in kidney cells relates to glucose concentration. Human kidney HK-2 cells were infected with different ZIKV strains in presence of normal and high glucose concentrations. Virological assays showed a decrease in viral replication without modifying entry steps (viral binding, internalization, fusion) under high glucose conditions. This decrease replication was associated with a lower virus progeny and increased cell viability when compared to ZIKV-infected HK-2 cells in normal glucose concentration. In conclusion, we showed for the first time that an elevated glucose level influences ZIKV replication level with an effect on kidney cell survival. 相似文献
2.
Yuelong Ma Le Zhang Tianyuan Zhou Bingheng Sun Chen Hou Shunshun Yang Jin Huang Rui Wang Farida A. Selim Zhongying Wang Ming Li Hao Chen Yun Wang 《Journal of the European Ceramic Society》2021,41(4):2834-2846
Ce:Y3Al5O12 transparent ceramics (TCs) with appropriate emission light proportion and high thermal stability are significant to construct white light emitting diode devices with excellent chromaticity parameters. In this work, strategies of controlling crystal-field splitting around Ce3+ ion and doping orange-red emitting ion, were adopted to fabricate Ce:(Y,Tb)3(Al,Mn)5O12 TCs via vacuum sintering technique. Notably, 85.4 % of the room-temperature luminescence intensity of the TC was retained at 150 °C, and the color rendering index was as high as 79.8. Furthermore, a 12 nm red shift and a 16.2 % increase of full width at half maximum were achieved owing to the synergistic effects of Tb3+ and Mn2+ ions. By combining TCs with a 460 nm blue chip, a warm white light with a low correlated color temperature of 4155 K was acquired. Meanwhile, the action mechanism of Tb3+ ion and the energy transfer between Ce3+ and Mn2+ ions were verified in prepared TCs. 相似文献
3.
Aziz Boutouil Ilhame Elazhary Hicham Ben El Ayouchia Hafid Anane Mohammadine El Haddad 《Journal of Adhesion Science and Technology》2020,34(5):549-578
Abstract4-[4-(1H-imidazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl]methylbenzophenone (ITBP) and 4[4-(1H-1,2,4-triazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl]methylbenzophenone (TTBP) are synthesized as new heterocyclic compounds of the triazole derivative family and tested successfully as potential inhibitors for MS in 1?M H2SO4 corrosive medium by using gravimetric analysis, electrochemical impedance spectroscopy, potentiodynamic polarization, and energy dispersive X-ray spectroscopy (EDX). Polarization curves show that the tested inhibitors are mixed-type inhibitors. Scanning electron microscopy (SEM) affirmed the existence of an adsorbed film on the steel surface. Monte Carlo simulations were in excellent agreement with the experimental tests. Abbreviation: PDP: Potentiodynamic Polarization; EIS: Electrochemical impedance spectroscopy; DFT: Density functional theory; MC: Monte Carlo 相似文献
4.
N Haddad R Ben Khelifa H Matter H Kharmachi MF Aubert A Wandeler J Blancou 《Canadian Metallurgical Quarterly》1994,12(4):307-309
The possibility of immunizing dogs orally against rabies, using SADBern, an attenuated strain, was tested on dogs in the field in Tunisia. This strain induced high neutralizing antibody titres and conferred to all vaccinated dogs total resistance against a challenge with a Maghrebian strain. However, an excretion of virus of vaccinal origin was observed in one dog, hampering the use of SADBern in dogs. Nevertheless, this work demonstrates for the first time that dogs in developing countries, especially those which are inaccessible to parenteral vaccination, could be efficiently immunized against rabies by the oral route. 相似文献
5.
Bernard G. Duda A. Haddad Y. Harrus G. 《IEEE transactions on pattern analysis and machine intelligence》1989,15(12):1567-1578
Epsilon is a testbed for monitoring distributed applications involving heterogeneous computers, including microcomputers, interconnected by a local area network. Such a hardware configuration is usual but raises difficulties for the programmer. First, the interprocess communication mechanisms provided by the operating systems are rather cumbersome to use. Second, they are different from one system to another. Third, the programmer of distributed applications should not worry about system and/or network aspects that are not relevant for the application level. The authors present the solution chosen in Epsilon. A set of high-level communication primitives has been designed and implemented to provide the programmer with an interface independent of the operating system and of the underlying interprocess communications facilities. A program participating in a distributed application can be executed on any host without any change in the source code except for host names 相似文献
6.
C Kooli M Salem A Hamzaoui M Fredj Z Kaouache N Khalfallah A Chabbou A Haddad 《Canadian Metallurgical Quarterly》1997,53(1):51-56
MCF7 and ZR75-1 breast cancer cells grow as adherent monolayers in tissue culture. Treatment with the serum serine protease plasmin causes them to detach and to grow as floating multicellular spheroids. Two plasmin activators, urokinase plasminogen activator and streptokinase, induce the same growth pattern changes in the presence of plasminogen. Serum contains also plasminogen activator inhibitors. Aged serum, deficient in plasminogen activator inhibitors, converts spontaneously monolayer breast cancer cells into multicellular spheroids which readily revert to monolayer growth after addition of fresh serum. Urokinase blocks the reversion. The formation of multicellular spheroids does not affect the proliferative rate of breast tumor cells but endows tumor cells with increased resistance to the chemotherapeutic drugs, doxorubicin and paclitaxel. 相似文献
7.
Adaptive median filters: new algorithms and results 总被引:39,自引:0,他引:39
Based on two types of image models corrupted by impulse noise, we propose two new algorithms for adaptive median filters. They have variable window size for removal of impulses while preserving sharpness. The first one, called the ranked-order based adaptive median filter (RAMF), is based on a test for the presence of impulses in the center pixel itself followed by a test for the presence of residual impulses in the median filter output. The second one, called the impulse size based adaptive median filter (SAMF), is based on the detection of the size of the impulse noise. It is shown that the RAMF is superior to the nonlinear mean L(p) filter in removing positive and negative impulses while simultaneously preserving sharpness; the SAMF is superior to Lin's (1988) adaptive scheme because it is simpler with better performance in removing the high density impulsive noise as well as nonimpulsive noise and in preserving the fine details. Simulations on standard images confirm that these algorithms are superior to standard median filters. 相似文献
8.
We have evaluated the extent of public concerns about water management in the Palestinian Territory (PT) through a survey of the main Palestinian newspaper over the last thirteen years divided in three periods: pre (1984–1987), during (1988–1991), and post national uprising period (1992–1996). The public concern in the PT about various water management aspects was clear and influenced by the prevailing political conditions indicating (1) poor concerns in the first and second period where full Israeli military control of the PT and harsh practices prevailed with relatively more emphasis on regional water issues and (2) extensive-strong concerns in the third period when the peace process started and a partial lift of some of the Israeli water practices took place, along with an increased freedom in expressing public concerns which was granted with more emphasis on local issues and problems. Lack and limitation of water available to Palestinians, alternative solutions, and water quality and pollution control constituted the overwhelming majority of the topics of concern to the public for the three periods studied. Palestinian concerns were always greater than regional ones for the three periods and all of the topics considered. Public concern in the PT about all other water management aspects was poor and negligible especially in the first two periods. A massive increase in public concern has been observed in the third period in which the public expressed their concern over most water management aspects, indicating a possible change in public attitude toward water and water management and reflecting the change of the political status by the start of the peace process and the signing of the peace agreements. 相似文献
9.
The feasibility of using a thick ground plane with an aperture coupled microstrip patch antenna while maintaining reasonable antenna performance is demonstrated using moment method and reciprocity analyses in the spectral domain. The thick ground plane, which may serve as a heatsink for active MMIC circuitry, or as a mechanical support for thin substrates, is particularly advantageous in millimetre wave phased array applications. It is found that the effect of ground plane thickness is to reduce the level of coupling from the feed line to the patch 相似文献
10.