Assessing the usefulness of bibliometric indicators for the humanities and the social and beha vioural sciences: A comparative study

An evaluation was made of the use of bibliometric indicators for five disciplines in the humanities (social history, general linguistics, general literature, Dutch literature, and Dutch language) and three disciplines in the social and behavioural sciences (experimental psychology, anthropology, and public administration) in the Netherlands. Articles in journals were the predominant outlet in all disciplines. Monographs and popularizing articles were more important outlets in softer fields than in harder ones. The enlightenment function of scholarship was especially evident in Dutch literature and language, and public administration. Only some of the humanities disciplines are locally oriented. Although many publications were written in English, only experimental psychology, general linguistics, anthropology, and genrral literature were internationally oriented regarding output media. The impact of departments differed greatly both within and between disciplines. For all disciplines, bibliometric indicators are potentially useful for monitoring international impact, as expert interviews confirmed. Especially in Dutch language, Dutch literature and public administration, ISI-citation data are not very useful for monitoring national impact.     

Congenital fibrosis of the extraocular muscles type 2, an inherited exotropic strabismus fixus, maps to distal 11q13

The extraocular fibrosis syndromes are congenital ocular-motility disorders that arise from dysfunction of the oculomotor, trochlear, and abducens nerves and/or the muscles that they innervate. Each is marked by a specific form of restrictive paralytic ophthalmoplegia with or without ptosis. Individuals with the classic form of congenital fibrosis of the extraocular muscles (CFEOM1) are born with bilateral ptosis and a restrictive infraductive external ophthalmoplegia. We previously demonstrated that CFEOM1 is caused by an autosomal dominant locus on chromosome 12 and results from a developmental absence of the superior division of the oculomotor nerve. We now have mapped a variant of CFEOM, exotropic strabismus fixus ("CFEOM2"). Affected individuals are born with bilateral ptosis and restrictive ophthalmoplegia with the globes "frozen" in extreme abduction. This autosomal recessive disorder is present in members of three consanguineous Saudi Arabian families. Genetic analysis of 70 individuals (20 affected individuals) reveals linkage to markers on chromosome 11q13, with a combined LOD score of 12.3 at the single nonrecombinant marker, D11S1314. The 2.5-cM CFEOM2 critical region is flanked by D11S4196/D11S4162 and D11S4184/1369. Two of the three families share a common disease-associated haplotype, suggesting a founder effect for CFEOM2. We hypothesize that CFEOM2 results from an analogous developmental defect to CFEOM1, one that affects both the superior and inferior divisions of the oculomotor nerve and their corresponding alpha motoneurons and extraocular muscles.     

Updating Situation Models.

The authors examined how situation models are updated during text comprehension. If comprehenders keep track of the evolving situation, they should update their models such that the most current information, the here and now, is more available than outdated information. Contrary to this updating hypothesis, E. J. O'Brien, M. L. Rizzella, J. E. Albrecht, and J. G. Halleran (1998) obtained results suggesting that outdated or incorrect information may still influence the comprehension process. The authors of the current study demonstrate that the nature of E. J. O'Brien et al.'s materials were the likely cause of this pattern of results. Hence, the current authors constructed materials that circumvent identified confounds and in a reading-time experiment obtained evidence supporting the here-and-now hypothesis. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Eye findings in patients with phenylketonuria

Untreated phenylketonuria (PKU) is characterized by excretion of phenylpyruvic acid in the urine and mental retardation. Reported eye abnormalities include photophobia (probably due to the albinoid iris), cataracts, and corneal opacities. Eleven patients in an institutionalized population of approximately 1,000 mentally retarded patients had PKU. Cataracts were found in six patients. One patient had bilateral phthisis bulbi and one patient had monocular phthisis. No corneal opacities were found otherwise. All patients with cataracts were middle-aged or had a history of severe self-induced trauma or treatment with high dosages of thioridazine hydrochloride. Albinism is associated with anomalous chiasmal routing of optic fibers and abnormal, extraocular motility. The ocular hypopigmentation of patients with PKU did not have the same results; all seeing patients were orthophoric. Although eye abnormalities are common in PKU except for hypopigmentation, none can be considered a direct effect of the inborn error of metabolism.     

Inhibition of smoking-related information in smokers and nonsmokers.

Twenty-four smokers and 24 nonsmokers performed a modified version of M. A. Gemsbacher, K. R. Varner, and M. E. Faust's (1990) suppression task, involving presentations of sentences on a computer screen. Each sentence was followed by a word that either was or was not related to the meaning of the sentence. Participants judged whether the word was related to the sentence by pressing either a "yes" or "no" key on a button box. In the experimental sentences, the test word was related to one meaning of the final word of the sentence, but this was not necessarily the meaning intended in the sentence. In half of the experimental sentences, the last word was a smoking-related word (e.g., tar or ashes). Smokers had relatively longer response latencies and lower accuracy scores than nonsmokers when the final word was smoking related, whereas both groups performed similarly on items unrelated to smoking, suggesting that smokers had more difficulty than nonsmokers inhibiting task-irrelevant, smoking-related information but that they did not have a general inability to inhibit irrelevant information. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Brief report: Aging and functional spatial relations in comprehension and memory.

Previous research has suggested that, relative to younger adults, older adults devote a greater proportion of their discourse processing to the situation model level. The current experiment assessed whether this is due, in part, to a preserved ability to focus on functionally appropriate information. The focus here was on spatial relations. Both reading time and recognition data showed superior performance for functional over nonfunctional information, and this functional effect was similar in younger and older adults. This is consistent with the idea that older adults' ability to process information at the situation model level is relatively well preserved. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Situation models in language comprehension and memory

This article reviews research on the use of situation models in language comprehension and memory retrieval over the past 15 years. Situation models are integrated mental representations of a described state of affairs. Significant progress has been made in the scientific understanding of how situation models are involved in language comprehension and memory retrieval. Much of this research focuses on establishing the existence of situation models, often by using tasks that assess one dimension of a situation model. However, the authors argue that the time has now come for researchers to begin to take the multidimensionality of situation models seriously. The authors offer a theoretical framework and some methodological observations that may help researchers to tackle this issue.     

Clinical experience with temporary vena caval filters

PURPOSE: To look at the benefits and complications of different vena caval filters inserted prophylactically. Three temporarily implantable caval filter systems were used in 67 patients. MATERIALS AND METHODS: Twelve Cook filters (six transjugular, six transfemoral), 11 Angiocor filters (one transjugular, 10 transbrachial), and 44 Antheor filters (three transjugular, four transfemoral, 37 transbrachial) were successfully implanted. In known iliac vein or caval thrombosis, the prophylactic filters were placed during thrombolytic therapy in 46 cases, surgery in 17 cases, thrombosis in pregnancy in three cases, and high-dose heparinization without lysis in one case. RESULTS: One patient had a fatal pulmonary embolism during treatment; seven thrombi were detected in the filter. Other complications were caused either by the underlying therapy alone (one fatal outcome of abdominal aorta aneurysmal surgery, two cases of cerebral hemorrhage, two cases of retroperitoneal hematomas, two cases of streptokinase fever reactions, one compartment syndrome, two cases of macrohematuria), by the combination of therapy and caval filter implantation (three cases of groin hematomas, three cases of arm hematomas), or by filter implantation alone (two cases of subclavian vein thrombosis, one catheter infection, one dislocation, one air embolism, one basket rupture). The bleeding complications were related to the aggressive thrombolytic therapy and would have occurred without filter implantation. CONCLUSION: Because temporary caval filters have no long-term complications per se, their use seems sensible as long as there are stringent indications, including the presence of iliac vein or caval thrombosis and risk of thrombus mobilization. The Antheor filter system was the most convenient system for implantation.     

Autograft failure after the Ross operation in a rheumatic population: pre- and postoperative echocardiographic observations

BACKGROUND AND AIMS OF THE STUDY: Between January 1990 and July 1995, 108 patients underwent the Ross operation at our hospital. Most patients (90%) had severe aortic regurgitation (AR) in the setting of rheumatic heart disease. Although there have been no perioperative or late cardiac deaths, 12 patients (11%) developed severe AR requiring reoperation. MATERIAL AND METHODS: We performed an extensive and mostly retrospective analysis of echocardiographic data on all patients. Preoperative data were analyzed for age, sex, body surface area (BSA), size and comparison of the left and right ventricular outflow tracts (LVOT, RVOT), left ventricular (LV) size and function, and the presence of pulmonary regurgitation (PR) and concomitant mitral regurgitation (MR). Follow up data were analyzed for the presence, time of onset, evolution and severity of AR, characteristics of the AR jet, anatomic and functional aspects of the aortic root and valve, and evolution of LVOT diameter and LV size and function. RESULTS: Patients with autograft failure were younger with smaller BSA, larger indexed size of LVOT, RVOT and LV, and significantly more had concomitant severe MR. Postoperatively they had larger and increasing LVOT size. Trivial or mild AR was common and seen in almost all patients, as was a minimal degree of preoperative PR. Severe AR developed mostly after the first year of follow up, and reoperation was performed within three years in 11/12 patients. In nine patients cusp dilatation and prolapse (most frequently of the posterior cusp) was the cause of the AR, and rheumatic activity in three. Reoperation was not associated with mortality. CONCLUSION: In our population autograft failure seems to be related to age, BSA and (indexed) LVOT, RVOT and LV size, but only the presence of significant concomitant mitral regurgitation before surgery was identified as a predictor for reoperation. Prolapse of one or more cusps were the cause of the AR in most patients. The graft is sensitive for recurrent rheumatic activity.