Classification of acute lymphoblastic leukaemia using hybrid hierarchical classifiers

Multimedia Tools and Applications - In current consequence of haematology, blood cancer i.e. acute lymphoblastic leukemia is very frequently founded in medical practice, which is characterized by...     

Fibrillized peptide microgels for cell encapsulation and 3D cell culture

One of the advantages of materials produced by self-assembly is that in principle they can be formed in any given container to produce materials of predetermined shapes and sizes. Here, we developed a method for triggering peptide self-assembly within the aqueous phase of water-in-oil emulsions to produce spherical microgels composed of fibrillized peptides. Size control over the microgels was achieved by specification of blade type, speed, and additional shear steps in the emulsion process. Microgels constructed in this way could then be embedded within other self-assembled peptide matrices by mixing pre-formed microgels with un-assembled peptides and inducing gelation of the entire composite, offering a route towards multi-peptide materials with micron-scale domains of different peptide formulations. The gels themselves were cytocompatible, as was the microgel fabrication procedure, enabling the encapsulation of NIH 3T3 fibroblasts and C3H10T-1/2 mouse pluripotent stem cells with good viability.     

Adsorptive separation of Kr from N2 — Part I Adsorbent screening studies

Results of a chromatographic study of the adsorption of N₂ and Kr on several molecular sieve adsorbents are reported. The objective was to find a suitable adsorbent for the removal of traces of radioactive Kr from the off-gas from nuclear fuel reprocessing facilities. Of the adsorbents examined, de-aluminated H-mordenite shows the highest selectivity for Kr relative to N₂ and appears to be a promising adsorbent for this separation. The presence of traces of NO₂, a likely impurity in the off-gas, was found to suppress the adsorption of N₂ more than that of Kr, thereby increasing the separation factor (α ∼ 12). In most of the adsorbents investigated, intracrystalline diffusion was too fast to measure but for N₂ in H-mordenite, intracrystalline resistance was found to be significant and strongly dependent on the initial dehydration temperature.