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To investigate the developmental distribution of cochlear nucleus (CN) astrocytes, we used immunocytochemical localization of glial fibrillary acidic protein (GFAP) and S100beta in rats at 0, 5, 10, 15, 21, 30 postnatal days plus the adult. Differential developmental trends were observed for both proteins. The spatial distribution showed a progressive increase of the number of GFAP-immunoreactive (GFAP-IR) astrocytes during development. GFAP positive cells occurred first in the granule cell domain of the ventral CN and in the molecular cell layer of the dorsal CN, then followed an outside to inside pattern of progression. The GFAP-IR reached an adult distribution 1 month after birth. By contrast with GFAP, the apparition of S100beta-immunoreactivity (S100beta-IR) was abrupt (between 0 and 5 days) followed by a rapid stabilization of density and distribution of IR cells (between 15 and 21 days). The developmental distribution of S100beta-IR cells occurred from the posterodorsal region and progressed toward a rostroventral direction. With contrast to GFAP-IR astrocytes, S100beta-positive cells were mainly restricted to the central part of the CN, while only few IR astrocytes were observed in the granule cell domain of the ventral CN or in the molecular cell layer of the dorsal CN. This differential distribution suggests that both antigens were expressed by two different cell populations at least, it is obvious during the first postnatal week. The gradual expression of GFAP and S100beta is interpreted as reflecting the time course of astrocytic maturation. These data suggest that the maturation of CN astrocytes may be linked to the final maturation of CN neurons.  相似文献   
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This paper addresses the problem of localization in sensor networks where, initially, a certain number of sensors are aware of their positions (either by using GPS or by being hand‐placed) and are referred to as anchors. Our goal is to localize all sensors with high accuracy, while using a limited number of anchors. Sensors can be equipped with different technologies for signal and angle measurements. These measures can be altered by some errors because of the network environment that induces position inaccuracies. In this paper, we propose a family (AT‐Family) of three new distributed localization techniques in wireless sensor networks: free‐measurement (AT‐Free) where sensors have no capability of measure, signal‐measurement (AT‐Dist) where sensors can calculate distances, and angle‐measurement (AT‐Angle) where sensors can calculate angles. These methods determine the position of each sensor while indicating the accuracy of its position. They have two important properties: first, a sensor node can deduce if its estimated position is close to its real position and contribute to the positioning of others nodes; second, a sensor can eliminate wrong information received about its position. This last property allows to manage measure errors that are the main drawback of measure‐based methods such as AT‐Dist and AT‐Angle techniques. By varying the density and the error rate, simulations show that the three proposed techniques achieve good performances in term of high accuracy of localized nodes and less energy consuming while assuming presence of measure errors and considering low number of anchors. Copyright © 2012 John Wiley & Sons, Ltd.  相似文献   
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Mobile Networks and Applications - With the rapid development in wireless technologies and the Internet, the Internet of Things (IoT) is envisioned to be an integral part of our daily lives....  相似文献   
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To determine the hepatitis C virus (HCV) genotypes circulating in Morocco, virus isolates from 105 chronically infected and 19 hemodialysis patients were examined using the line probe assay. Genotypes 1 and 2 only were found among Moroccan patients. Subtypes 1b (47.6%) and 2a/2c (37.1%) were the most common, whereas subtype 1a (2.8%) was less common. Among the hemodialysis patients, only genotype 1 was found with a prevalence of 68.4% for subtype 1b and 15.8% for the subtype 1a. It was also shown that the HCV genotypes distribution varies with age in both studied populations. Subtype 1b was most prevalent among older patients, whereas subtype 2a/2c was mainly found among younger ones. Although Morocco belongs to the African continent, the circulating HCV strains are similar to those observed in some American and European countries.  相似文献   
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Views in composite Web services   总被引:1,自引:0,他引:1  
The authors present a view-based approach for tracking personalized Web services. To guarantee proper handling of user preferences during Web service execution, a view can zoom into the specification that composes the Web services. As time advances, the location changes, or constraints on the environment are satisfied, the deployment of a view over a specification similarly progresses, mirroring the context's dynamic nature.  相似文献   
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