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Neural Computing and Applications - Marston’s load theory is commonly used for understanding the soil–conduit interaction. However, there are no practical methods available which can...  相似文献   
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Autonomous mapping of HL7 RIM and relational database schema   总被引:1,自引:0,他引:1  
Healthcare systems need to share information within and across the boundaries in order to provide better care to the patients. For this purpose, they take advantage of the full potential of current state of the art in healthcare standards providing interoperable solutions. HL7 V3 specification is an international message exchange and interoperability standard. HL7 V3 messages exchanged between healthcare applications are ultimately recorded into local healthcare databases, mostly in relational databases. In order to bring these relational databases in compliance with HL7, mappings between HL7 RIM (Reference Information Model) and relational database schema are required. Currently, RIM and database mapping is largely performed manually, therefore it is tedious, time consuming, error prone and expensive process. It is a challenging task to determine all correspondences between RIM and schema automatically because of extreme heterogeneity issues in healthcare databases. To reduce the amount of manual efforts as much as possible, autonomous mapping approaches are required. This paper proposes a technique that addresses the aforementioned mapping issue and aligns healthcare databases to HL7 V3 RIM specifications. Furthermore, the proposed technique has been implemented as a working application and tested on real world healthcare systems. The application loads the target healthcare schema and then identifies the most appropriate match for tables and the associated fields in the schema by using domain knowledge and the matching rules defined in the Mapping Knowledge Repository. These rules are designed to handle the complexity of semantics found in healthcare databases. The GUI allows users to view and edit/re-map the correspondences. Once all the mappings are defined, the application generates Mapping Specification, which contains all the mapping information i.e. database tables and fields with associated RIM classes and attributes. In order to enable the transactions, the application is facilitated with the autonomous code generation from the Mapping Specification. The Code Generator component focuses primarily on generating custom classes and hibernate mapping files against the runtime system to retrieve and parse the data from the data source—thus allows bi-directional HL7 to database communication, with minimum programming required. Our experimental results show 35–65% accuracy on real laboratory systems, thus demonstrating the promise of the approach. The proposed scheme is an effective step in bringing the clinical databases in compliance with RIM, providing ease and flexibility.  相似文献   
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Multimedia Tools and Applications - Nowadays, web users frequently explore multimedia contents to satisfy their information needs. The exploration approaches usually provide linear interaction...  相似文献   
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Breast cancer (BC) is a most spreading and deadly cancerous malady which is mostly diagnosed in middle-aged women worldwide and effecting beyond a half-million people every year. The BC positive newly diagnosed cases in 2018 reached 2.1 million around the world with a death rate of 11.6% of total cases. Early diagnosis and detection of breast cancer disease with proper treatment may reduce the number of deaths. The gold standard for BC detection is biopsy analysis which needs an expert for correct diagnosis. Manual diagnosis of BC is a complex and challenging task. This work proposed a deep learning-based (DL) solution for the early detection of this deadly disease from histopathology images. To evaluate the robustness of the proposed method a large publically available breast histopathology image database containing a total of 277524 histopathology images is utilized. The proposed automatic diagnosis of BC detection and classification mainly involves three steps. Initially, a DL model is proposed for feature extraction. Secondly, the extracted feature vector (FV) is passed to the proposed novel feature selection (FS) framework for the best FS. Finally, for the classification of BC into invasive ductal carcinoma (IDC) and normal class different machine learning (ML) algorithms are used. Experimental outcomes of the proposed methodology achieved the highest accuracy of 92.7% which shows that the proposed technique can successfully be implemented for BC detection to aid the pathologists in the early and accurate diagnosis of BC.  相似文献   
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A growing trend within nanomedicine has been the fabrication of self‐delivering supramolecular nanomedicines containing a high and fixed drug content ensuring eco‐friendly conditions. This study reports on green synthesis of silica nanoparticles (Si‐NPs) using Azadirachta indica leaves extract as an effective chelating agent. X‐ray diffraction analysis and Fourier transform‐infra‐red spectroscopic examination were studied. Scanning electron microscopy analysis revealed that the average size of particles formed via plant extract as reducing agent without any surfactant is in the range of 100–170 nm while addition of cetyltrimethyl ammonium bromide were more uniform with 200 nm in size. Streptomycin as model drug was successfully loaded to green synthesised Si‐NPs, sustain release of the drug from this conjugate unit were examined. Prolong release pattern of the adsorbed drug ensure that Si‐NPs have great potential in nano‐drug delivery keeping the environment preferably biocompatible, future cytotoxic studies in this connection is helpful in achieving safe mode for nano‐drug delivery.Inspec keywords: silicon compounds, nanofabrication, nanomedicine, drug delivery systems, nanoparticles, X‐ray diffraction, Fourier transform infrared spectra, scanning electron microscopyOther keywords: nanosilica, streptomycin, nanoscale drug delivery, nanomedicine, silica nanoparticles, Azadirachta indica leaves extract, X‐ray diffraction analysis, Fourier transform‐infrared spectroscopy, scanning electron microscopy, cetyltrimethyl ammonium bromide, SiO2   相似文献   
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This paper mainly addresses formation control problem of non-holonomic systems in an optimized manner. Instead of using linearization to solve this problem approximately, we designed control laws with guaranteed global convergence by leveraging nonlinear transformations. Under this nonlinear transformation, consensus of non-holonomic robots can be converted into a stabilization problem, to which optimal treatment applies. This concept is then extended to the formation control and tracking problem for a team of robots following leader-follower strategy. A trajectory generator prescribes the feasible motion of virtual reference robot, a decentralized control law is used for each robot to track the reference while maintaining the formation. The asymptotic convergence of follower robots to the position and orientation of the reference robot is ensured using the Lyapunov function which is also generated using chained form differential equations. In order to witness the efficacy of the scheme, simulations results are presented for Unicycle and Car-like robots.  相似文献   
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On web information exists in the form of text, audio, image, and video objects often referred to multiple media objects. Vertical web search provides the search of multiple media information usually via keyword-based queries. The search results in different media formats usually presented in separate panels/tabs; integration is mostly non-blended. Therefore, results exploration via vertical web search engines require the selection of a source and scrolling of a linear ranked list of results. Relationships in the results presented in separate panels/tabs are mostly not considered. Search aggregations unify results from several vertical web sources via blended integration, but exploration still requires scrolling of a linear ranked list. Multimedia search frameworks provide the exploration of results in different media formats but more focused towards the retrieval issues. We proposed a multiple media information search framework to address issues, particularly in aggregated search. Our search framework provides a mechanism to explore results via non-linear ways. The search framework realized by suggesting a framework architecture design and instantiating a search tool. The effectiveness of blended integration and browsing is measured via precision and click through rate respectively. Search task support in results exploration mechanism measured via task-based evaluation. We also validated the conformance of various search/exploration attributes discussed in the state-of-the-art in our frameworks.  相似文献   
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