The efficiency of private and public schools in urban and rural areas: moving beyond the development goals

Data from the Young Lives study are used to evaluate the efficiency of education systems in four low and middle income countries: Ethiopia, India, Peru and Vietnam. A meta‐frontier variant of data envelopment analysis is used to assess the relative performance of each country's system, and, within each country, to evaluate the impact of public and private schooling, and of urban and rural location. Comparisons are drawn between the four countries; the results indicate that in no country does the educational system perform uniformly badly or well. Conditioning on the inputs available, rural areas are often indicative of higher levels of efficiency, thus suggesting a number of implications for policy.     

Comparison of molecular changes in lung cancers in HIV-positive and HIV-indeterminate subjects

CONTEXT: Human immunodeficiency virus (HIV) infection has been associated with an increasing incidence of malignancy, and HIV-infected persons have an increased incidence of primary lung carcinoma compared with the general population. OBJECTIVE: To investigate the molecular changes present in HIV-associated lung tumors and compare them with those present in lung carcinomas arising in HIV-indeterminate subjects ("sporadic tumors"). DESIGN: Convenience sample. SUBJECTS: Archival tissues from 11 HIV-positive persons and from 35 persons of indeterminate HIV status. SETTING: University-based medical centers and affiliated hospitals. MAIN OUTCOME MEASURES: Analysis of frequency of loss of heterozygosity (LOH) and microsatellite alteration (MA) using polymerase chain reaction and 16 polymorphic microsatellite markers at 8 chromosomal regions frequently deleted in lung cancer. Presence of HIV and human papillomavirus (HPV) sequences. RESULTS: The overall frequency of LOH at all chromosomal regions tested and the frequencies at most of the individual regions were similar in the 2 groups. Frequency of MA present in the HIV-associated tumors (0.18) was 6-fold higher than in sporadic tumors (0.03) (P<.001). At least 1 MA was present in 10 (91%) of 11 HIV-associated tumors vs 17 (48%) of 35 sporadic tumors (P=.02). Molecular changes were independent of tumor stage and gender. HIV and HPV sequences were not detected in the HIV-associated lung carcinomas. CONCLUSIONS: Microsatellite alterations, which reflect widespread genomic instability, occur at greatly increased frequency in HIV-associated lung carcinomas. Although the mechanism underlying the development of increased MAs is unknown, it may play a crucial role in the development of many HIV-associated tumors.     

Classification of acute lymphoblastic leukaemia using hybrid hierarchical classifiers

Multimedia Tools and Applications - In current consequence of haematology, blood cancer i.e. acute lymphoblastic leukemia is very frequently founded in medical practice, which is characterized by...     

In the Hands of the People: Harnessing the Collective Power of Village Life in India

Top-down attempts by governments and charities to rebuild rural communities after natural disasters, or to rehabilitate slums, can leave communities feeling fractured. The Hunnarshala Foundation instead focuses on re-establishing social capital, providing funding and professional support for residents so that they can work together to improve their lot. This also reinforces the value of traditional artisans' knowledge in solving modern problems. Hunnarshala's Executive Vice Chairman Sandeep Virmani explains.     

DMajor—Application Programming Interface for Database Mining

In the process of rule generation from databases, the volume of generated rules often greatly exceeds the size of the underlying database. Typically only a small fraction of that large volume of rules is of any interest to the user. We believe that the main challenge facing database mining is what to do with the rules after having generated them. Rule post-processing involves selecting rules which are relevant or interesting, building applications which use the rules and finally, combining rules together to form a larger and more meaningful statements. In this paper we propose an application programming interface which enables faster development of applications which rely on rules. We also provide a rule query language which allows both selective rule generation as well as retrieval of selected categories of rules from the pre-generated rule collections.     

Risk factors in the pathogenesis of coronary artery disease

In men, plaque rupture is strongly correlated with total cholesterol, and smoking is a predictor of acute thrombosis. In women younger than 50, plaque erosion correlates with smoking, whereas in women older than 50, thrombosis is secondary to plaque rupture and correlates with total cholesterol.     

Implementation of a Lagrangian relaxation based unit commitmentproblem

An effort is made to provide an understanding of the practical aspects of the Lagrangian relaxation methodology for solving the thermal unit commitment problem. Unit commitment is a complex, mixed integer, nonlinear programming problem complicated by a small set of side constraints. Until recently, unit commitment for realistic size system has been solved using heuristic approaches. The Lagrangian relaxation offers a new approach for solving such problems. Essentially, the method involves decomposition of the problem into a sequence of master problems and easy subproblems, whose solutions converge to an ϵ-optimal solution to the original problem. The authors concentrate on the implementation aspects of the Lagrangian relaxation method applied to realistic and practical unit commitment problems