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排序方式: 共有802条查询结果,搜索用时 15 毫秒
1.
The aim of this study was to bring to the surface the strategic use of imitative processes in the context of a 2-route model: (a) direct imitation, used in reproducing new, meaningless actions, and (b) imitation based on stored semantic knowledge of familiar meaningful actions. Three experiments were carried out with healthy participants who reproduced meaningful and meaningless actions within an established time limit. The study investigated 3 factors that could potentially affect the selection of processes used for imitation: (a) the composition of the experimental list (blocked or mixed presentation), (b) the presence-absence of instructions (Experiments 1 and 2), and (c) the relative proportions of the stimuli (Experiment 3). Overall, the results suggest that each of these factors influences the selection of imitative strategies in healthy individuals with temporarily reduced capacities, as happens in the case of brain-damaged patients. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
2.
K Tani M Masuhara N Welikala N Yamaguchi M Nasu 《Canadian Metallurgical Quarterly》1998,84(5):859-864
A modification of the standard electrodiagnostic test was developed in an effort to provide a more sensitive electrodiagnostic evaluation in radial tunnel syndrome. Radial motor nerve latency recordings were obtained in 3 different forearm positions: neutral, passive supination, and passive pronation. The maximal difference in these recordings, the differential latency, in 25 patients with radial tunnel syndrome of greater than 6 months duration (test group) was compared with those in 25 asymptomatic volunteers (control group). Differential latency recordings were obtained in all patients in the test group before and after surgery. Radial nerves that were compressed demonstrated a significantly greater differential latency (0.44+/-0.12 ms) versus controls (0.12+/-0.008 ms). Following radial nerve decompression, differential motor latencies in the test group decreased below control values, demonstrating a resolution of the provoked electrical response with a postoperative differential latency of 0.07+/-0.05 ms. Our results demonstrate the differential motor latency of the radial nerve to be a sensitive electrodiagnostic tool in patients with radial tunnel syndrome. A differential latency of > or =0.30 ms was considered indicative of radial tunnel syndrome. 相似文献
3.
We report here a novel type of ceramidase of Pseudomonas aeruginosa AN17 isolated from the skin of a patient with atopic dermatitis. The enzyme was purified 83,400-fold with an overall yield of 21.1% from a culture supernatant of strain AN17. After being stained with a silver staining solution, the purified enzyme showed a single protein band, and its molecular mass was estimated to be 70 kDa on SDS-polyacrylamide gel electrophoresis. The enzyme showed quite wide specificity for various ceramides, i.e. it hydrolyzed ceramides containing C12:0-C18:0 fatty acids and 7-nitrobenz-2-oxa-1, 3-diazole-labeled dodecanoic acid, and not only ceramide containing sphingosine (d18:1) or sphinganine (d18:0) but also phytosphingosine (t18:0) as the long-chain base. However, the enzyme did not hydrolyze galactosylceramide, sulfatide, GM1, or sphingomyelin, and thus was clearly distinguished from a Pseudomonas sphingolipid ceramide N-deacylase (Ito, M., Kurita, T., and Kita, K. (1995) J. Biol. Chem. 270, 24370-24374). This bacterial ceramidase had a pH optimum of 8.0-9.0, an apparent Km of 139 microM, and a Vmax of 5.3 micromol/min/mg using N-palmitoylsphingosine as the substrate. The enzyme appears to require Ca2+ for expression of the activity. Interestingly, the 70-kDa protein catalyzed a reversible reaction in which the N-acyl linkage of ceramide was either cleaved or synthesized. Our study demonstrated that ceramidase is widely distributed from bacteria to mammals. 相似文献
4.
Prof. Alessia Carocci Dr. Mariagrazia Roselli Prof. Roberta Budriesi Dr. Matteo Micucci Prof. Jean-François Desaphy Dr. Concetta Altamura Dr. Maria Maddalena Cavalluzzi Dr. Maddalena Toma Dr. Giovanna Ilaria Passeri Dr. Gualtiero Milani Dr. Angelo Lovece Prof. Alessia Catalano Dr. Claudio Bruno Dr. Annalisa De Palma Prof. Filomena Corbo Prof. Carlo Franchini Prof. Solomon Habtemariam Prof. Giovanni Lentini 《ChemMedChem》2021,16(3):578-588
Under the hypothesis that cardioprotective agents might benefit from synergism between antiarrhythmic activity and antioxidant properties, a small series of mexiletine analogues were coupled with the 2,2,5,5-tetramethylpyrroline moiety, known for its antioxidant effect, in order to obtain dual-acting drugs potentially useful in the protection of the heart against post-ischemic reperfusion injury. The pyrroline derivatives reported herein were found to be more potent as antiarrhythmic agents than mexiletine and displayed antioxidant activity. The most interesting tetramethylpyrroline congener, a tert-butyl-substituted analogue, was at least 100 times more active as an antiarrhythmic than mexiletine. 相似文献
5.
Toshio Kimura Toru Takahashi Toshihiko Tani Yasuyoshi Saito 《Journal of the American Ceramic Society》2004,87(8):1424-1429
Bi0.5 Na0.5 TiO3 (BNT) and 0.94Bi0.5 Na0.5 TiO3 ·0.06BaTiO3 (BNT–BT) bulk ceramics with extensive 〈100〉 texture were prepared by the reactive-templated grain growth method, using platelike Bi4 Ti3 O12 (BIT) particles as templates for BNT. Calcined compacts were composed of matrix grains with random orientation and 〈100〉-oriented grains transformed from aligned BIT particles, and the texture developed by the growth of oriented grains during sintering. Ceramics with extensive texture were obtained by using the starting mixture containing the maximum concentration of platelike BIT to form the maximum volume fraction of oriented grains. 相似文献
6.
Apiwat Muttamara Yasushi Fukuzawa Naotake Mohri Takayuki Tani 《Journal of Materials Processing Technology》2003,140(1-3):243-247
Electrical discharge machining (EDM) is used as a precision machining method for the electrically conductive hard materials with a soft electrode material. But recently we succeeded to machine on insulating material by EDM. The technology is named as an assisting electrode method. The EDMed surface is covered with the electrical conductive layer during discharge. The layer holds the electrical conductivity during discharge. For micro-EDM, the wear of tool electrode becomes lager ratio than the normal machining. So the micro-machining is extremely difficult to get the precision sample.
In this paper to obtain a fine and precise ceramics sample, some trials were carried out considering the EDM conditions, tool electrodes material and assisting electrode materials. Insulating Si3N4 ceramics were used for workpiece. The machining properties were estimated by the removal rate and tool wear ratio. To confirm the change of micro-machining process, the discharge waveforms were observed. The micro-machining of the Ø0.05 mm hole could be machined with the commercial sinking electrical discharge machine. 相似文献
7.
Fusaomi Nagata Takanori Mizobuchi Shintaro Tani Tetsuo Hase Zenku Haga Keigo Watanabe Maki K. Habib 《Artificial Life and Robotics》2010,15(1):106-110
In this article, a new desktop orthogonal-type robot, which has the capacity of stick-slip motion control based on cutter
location data, is presented for lapping small metallic molds with a curved surface. The robot consists of three single-axis
devices with a high position resolution of 1 μm. A thin wooden stick tool with a ball-end shape is attached to the tip of
the z-axis. In order to improve the lapping performance, a novel stick-slip motion control method is developed in the control system.
The small stick-slip motion is orthogonally generated in the direction of the tool’s movement. The effectiveness of stick-slip
motion control is examined through an actual lapping test of an LED lens cavity. 相似文献
8.
Faith Ellen Panagiota Fatourou Eleftherios Kosmas Alessia Milani Corentin Travers 《Distributed Computing》2016,29(4):251-277
A universal construction is a general mechanism for obtaining a concurrent implementation of an object from its sequential code. We show that there is no universal construction that is both disjoint-access parallel (guaranteeing the processes operating on different parts of an implemented object do not interfere with one another) and wait-free (guaranteeing progress for each nonfaulty process when accessing an object). In contrast, we present a universal construction which results in disjoint-access parallel, wait-free implementations of any object provided there is a bound on the number of data items accessed by each operation supported by the object. 相似文献
9.
Codevelopmental learning between human and humanoid robot using a dynamic neural-network model. 总被引:1,自引:0,他引:1
Jun Tani Ryu Nishimoto Jun Namikawa Masato Ito 《IEEE transactions on systems, man, and cybernetics. Part B, Cybernetics》2008,38(1):43-59
This paper examines characteristics of interactive learning between human tutors and a robot having a dynamic neural-network model, which is inspired by human parietal cortex functions. A humanoid robot, with a recurrent neural network that has a hierarchical structure, learns to manipulate objects. Robots learn tasks in repeated self-trials with the assistance of human interaction, which provides physical guidance until the tasks are mastered and learning is consolidated within the neural networks. Experimental results and the analyses showed the following: 1) codevelopmental shaping of task behaviors stems from interactions between the robot and a tutor; 2) dynamic structures for articulating and sequencing of behavior primitives are self-organized in the hierarchically organized network; and 3) such structures can afford both generalization and context dependency in generating skilled behaviors. 相似文献
10.
Hiroaki Arie Takafumi Arakaki Shigeki Sugano Jun Tani 《Robotics and Autonomous Systems》2012,60(5):729-741
This paper introduces a novel neuro-dynamical model that accounts for possible mechanisms of action imitation and learning. It is considered that imitation learning requires at least two classes of generalization. One is generalization over sensory–motor trajectory variances, and the other class is on cognitive level which concerns on more qualitative understanding of compositional actions by own and others which do not necessarily depend on exact trajectories. This paper describes a possible model dealing with these classes of generalization by focusing on the problem of action compositionality. The model was evaluated in the experiments using a small humanoid robot. The robot was trained with a set of different actions concerning object manipulations which can be decomposed into sequences of action primitives. Then the robot was asked to imitate a novel compositional action demonstrated by a human subject which are composed from prior-learned action primitives. The results showed that the novel action can be successfully imitated by decomposing and composing it with the primitives by means of organizing unified intentional representation hosted by mirror neurons even though the trajectory-level appearance is different between the ones of observed and those of self-generated. 相似文献