Violence detection in videos for an intelligent surveillance system using MoBSIFT and movement filtering algorithm

Pattern Analysis and Applications - Action recognition is an active research area in computer vision as it has enormous applications in today’s world, out of which, recognizing violent action...     

Discovery of Affinity-Based Probes for Btk Occupancy Assays

Bruton's tyrosine kinase (Btk) is an attractive target for the treatment of a wide array of B-cell malignancies and autoimmune diseases. Small-molecule covalent irreversible Btk inhibitors targeting Cys481 have been developed for the treatment of such diseases. In clinical trials, probe molecules are required in occupancy studies to measure the level of engagement of the protein by these covalent irreversible inhibitors. The result of this pharmacodynamic (PD) activity provides guidance for appropriate dosage selection to optimize inhibition of the drug target and correlation of target inhibition with disease treatment efficacy. This information is crucial for successful evaluation of drug candidates in clinical trials. Based on the pyridine carboxamide scaffold of a novel solvent-accessible pocket (SAP) series of covalent irreversible Btk inhibitors, we successfully developed a potent and selective affinity-based biotinylated probe 12 (2-[(4-{4-[5-(1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-3,6,9,12-tetraoxapentadecan-15-amido)pentanoyl]piperazine-1-carbonyl}phenyl)amino]-6-[1-(prop-2-enoyl)piperidin-4-yl]pyridine-3-carboxamide). Compound 12 has been used in Btk occupancy assays for preclinical studies to determine the therapeutic efficacy of Btk inhibition in two mouse lupus models driven by TLR7 activation and type I interferon.     

Pinched Cord and Overdriven Staple Failures: Research on the Causation of an Electrical Fire

In the past, some fire investigators have determined the cause of a fire to be electrical in nature based, in part, on the presence of an electrical cord or cable found beneath a furniture leg or a cable wedged tightly under a staple. While fires resulting from these events are possible, the mechanisms that lead to these failures are poorly understood. In this paper, the results of four research projects are presented. The first three projects focused on the creation of a pinched cord failure under various current loads and pressures. In the last project, a typical nonmetallic-sheathed cable was damaged and then installed with an overdriven staple over the damaged location. In all tests, the cords and cables were subjected to current loads varying between 100 and 250% of the rated ampacity. The failure rate of pinched cords was approximately 1%, but required the use of overloaded circuits and pre-existing damage or special orientation of the cord under test. A critical factor worth considering with these failures, which is often not accounted for, is time. These failures may take weeks, months, or years to occur under normal conditions, although some investigators may assume they develop nearly instantaneously. The conditions of the circuit are also important, as the only way a failure developed in these tests was by operating the circuits in excess of their rated parameters.     

Source water quality effects on monochloramine inactivation of adenovirus, coxsackievirus, echovirus, and murine norovirus

There is a need for more information regarding monochloramine disinfection efficacy for viruses in water. In this study, monochloramine disinfection efficacy was investigated for coxsackievirus B5 (CVB5), echovirus 11 (E11), murine norovirus (MNV), and human adenovirus 2 (HAdV2) in one untreated ground water and two partially treated surface waters. Duplicate disinfection experiments were completed at pH 7 and 8 in source water at concentrations of 1 and 3 mg/L monochloramine at 5 and 15 °C. The Efficiency Factor Hom (EFH) model was used to calculate CT values (mg-min/L) required to achieve 2-, 3-, and 4-log₁₀ reductions in viral titers. In all water types, monochloramine disinfection was most effective for MNV, with 3-log₁₀ CT values at 5 °C ranging from 27 to 110. Monochloramine disinfection was least effective for HAdV2 and E11, depending on water type, with 3-log₁₀ CT values at 5 °C ranging from 1200 to 3300 and 810 to 2300, respectively. Overall, disinfection proceeded faster at 15 °C and pH 7 for all water types. Inactivation of the study viruses was significantly different between water types, but there was no indication that overall disinfection efficacy was enhanced or inhibited in any one water type. CT values for HAdV2 in two types of source water exceeded federal CT value recommendations in the US. The results of this study demonstrate that water quality impacts the inactivation of viruses and should be considered when developing chloramination plans.     

Book reviews

RESOURCE TRENDS AND POPULATION POLICY: A TIME FOR REASSESSMENT, by Lester R. Brown. Worldwatch Institute, Washington, D.C., May 1979; Worldwatch Paper 29. (Paperback $2.00)

THE NEXT SEVENTY YEARS: POPULATION, FOOD AND RESOURCES, by B. Gil‐land. Abacus Press, London, 1979. 133 pp. (£9.50)

POPULATION POLICY ANALYSIS, edited by M. E. Kraft and M. Schneider. D. C. Heath, London, 1979. (£0.00)

ENVIRONMENTAL IMPACT ASSESSMENT, by Brian B. Clark, Ronald Bisset and Peter Wath‐ern. Manssell, London and Bowker, New York, 1980. 516 pp. (£0.00)

ADVANCES IN ECOLOGICAL RESEARCH, Vol. 11, edited by Amyan MacFadyen. Academic Press, London, 1980. 428 pp. (£25.00)

MICROBIAL GROWTH AND SURVIVAL IN EXTREMES OF ENVIRONMENT, edited by G. W. Gould and Janet E. Cory. Academic Press, London, 1980. 244 pp. (£16.00)

UNDER NEW MANAGEMENT: Port Growth and Emerging Coastal Management Programs, by Marc Hershman, Robert Goodwin, Andrew Ruot‐sala, Maureen McCrea and Yehuda Hayuth. A Washington Sea Grant Publication, 1978. 212 pp. ($12.50)

HANDBOOK OF INDUSTRIAL ENERGY ANALYSIS, by J. Boustead and G. F. Hancock. Ellis‐Harwood, Chichester, U.K., 1979. (£25.00)

TREE GROWTH AND ENVIRONMENTAL STRESSES, by T. T. Kozlowski. University of Washington Press, Seattle and London, 1979. vii + 192 pp. (£12.50)

ALL GOOD THINGS AROUND US, by Pamela Michael. Illustrated by Christabel King. Ernest Benn Ltd., London, 1980. 240 pp. (£12.95)

HUMAN GEOGRAPHY (2nd Edition), by A. V. Perpillou. Longman Group, London, U.K., 1977. xviii + 570 pp. 37 pls., 27 maps and diagrams, Index. (Paperback £5.50)

INDUSTRIAL AND HAZARDOUS WASTES IMPOUNDMENT, by N. P. Cheremisinoff, P. N. Cheremisinoff, F. Ellerbeck and A. J. Perna. Ann Arbor Science, Michigan, 1979. ix + 475 pp. Index. (£16.25)

PHOSPHORUS IN THE ENVIRONMENT: ITS CHEMISTRY AND BIOCHEMISTRY. (Ciba Foundation No. 57, New Series), by Ruth Porter and David W. Fitzsimons. Elsevier, 1978. (£18.15)

TOXIC AND HAZARDOUS WASTE DISPOSAL. Vol. II, edited by R. B. Pojasek (Options for Sterilization Solidifications). Ann Arbor Science, Michigan, U.S.A., 1979, 259 pp. (£19.80)

SON OF THE WILDERNESS (The Life of John Muir), by Linnie Marsh Wolfe. The University of Wisconsin Press, Madison, 1978. 364 pp. (Paperback £4.90)

NATURE'S PRICE, by W. van Dieren and M. G. W. Hummelinck. Marion Boyars, London, Boston, 1979. (Paperback £3.50)

PERMACULTURE ONE, by Bill (B. C.) Molli‐son and David Holmgren. Corgi Books, Trans‐world Publishers Ltd., Melbourne, Australia. 128 pp. (A $4.95)

ENVIRONMENTAL AERODYNAMICS, by R. S. Scorer. Ellis Horwood, Chichester, U.K., 1978. 488 pp. (Hardback £20.00; paperback £7.50)     

Contact dynamic modeling of a liquid droplet between two approaching porous materials

A computational fluid dynamics model based on a finite difference solution to mass and momentum conservation equations (Navier–Stokes equations) for a liquid droplet transport between two porous or nonporous contacting surfaces (CSs) is developed. The CS dynamic (equation of motion) and the spread of the incompressible liquid available on the primary surface for transfer are coupled with the Navier–Stokes equations. The topologies of the spread dynamic between and inside both surfaces (primary and CSs) are compared with experimental data. The amount of mass being transferred into the CS, predicted by the model, is also compared to the experimental measurements. The impact of the initial velocity on the spread topology and mass transfer into the pores is addressed. © 2014 American Institute of Chemical Engineers AIChE J, 60: 2346–2353, 2014     

An Oral Male Courtship Pheromone Terminates the Response of Nasonia vitripennis Females to the Male-Produced Sex Attractant

Sex pheromones are crucial for mate finding in many animals. Long-range attraction, mate recognition, and the elicitation of sexual receptiveness during courtship are typically mediated by different compounds. It is widely unknown, however, how the different components of a species’ pheromone system influence each other. Here, we demonstrated in the parasitoid wasp Nasonia vitripennis that females quickly cease to respond to the male sex attractant after they contact a male’s oral secretion during courtship. We used this behavioral switch to monitor the fractionation of head extracts from male wasps for identification of the bioactive compounds as a blend of ethyl oleate, ethyl linoleate, and ethyl α-linolenate. This is the first identification of a cephalic courtship pheromone in parasitic Hymenoptera. Plasticity in pheromone-mediated sexual behavior of female insects has hitherto been attributed to the transfer of bioactive proteinaceous molecules with the male ejaculate. The pheromone interaction reported here sheds new light on the sexual communication of insects by showing that the sex pheromone response of females can be terminated by males independent of sperm transfer.     

Nitrogen dry deposition to Lake Superior and Lake Michigan

Nitrate (NO₃^?) levels in Lake Superior have increased from historic levels of about 5?μM to its current concentration of about 25?μM. The atmosphere makes a substantial contribution to the nitrogen budgets for Lake Superior and Lake Michigan. This study provides a more well-defined estimate of nitrogen dry deposition rates derived from the measurement of over-water concentrations, and in situ meteorological measurements, which were input into the Resistance Model. We obtained a nitrogen dry deposition rate of [(3.41?±?2.26)?×?10⁷?kg?N/yr; (5.90?±?3.91)?kg?N/ha/yr] over Lake Michigan, and [(1.54?±?1.06)?×?10⁷?kg?N/yr; (1.87?±?1.27)?kg?N/ha/yr] over Lake Superior. Nitric acid (HNO₃), which originates from the combustion of fossil fuels, contributes 84% of the total nitrogen dry deposition to Lake Michigan; and 66% to Lake Superior. Ammonia (NH₃), which originates from agricultural activities and gasoline combustion, is the second highest contributor of nitrogen dry deposition to both lakes: contributing 13% to Lake Michigan and 32% to Lake Superior. The nitrogen dry deposition is approximately 68% of the nitrogen wet deposition over Lake Superior, and approximately 80% of wet deposition over Lake Michigan. The over-water dry deposition velocity of HNO₃ and NH₃ were also evaluated. We obtained morning deposition velocities of 0.099?cm/s for NH₃ and 0.095?cm/s for HNO₃; and afternoon values of 0.137?cm/s for NH₃ and 0.132?cm/s for HNO₃. Another key finding is that the atmospheric concentrations of nitrogen compounds near Lake Michigan and Lake Superior have decreased since 2003.     

Fuzzy based genetic neural networks for the classification of murder cases using Trapezoidal and Lagrange Interpolation Membership Functions

This paper describes the construction of a decision system to be used by judges who is about to pass sentence in murder cases. Classification models of murder cases based on fuzzy neural network with random weights and fuzzy neural network with Genetic Algorithm based weights are designed. A simulation program in C++ has been deliberated and developed for analyzing the consequences. Results show that the fuzzy neural networks increase the rate of convergence in comparison with conventional neural networks with backpropagation algorithm. That the fuzzy neural networks for classification of murder cases using Trapezoidal Membership Function outperform Lagrange Interpolation and Gaussian Membership Function is also reported. Comparative studies are carried out for a number of networks and configurations.