急性炎性疾病患者乳酸林格氏液液体动力学

目的:探索炎性疾病患者的乳酸林格氏液（Ringer's lactate,RL）液体动力学特征以及炎性生物标记物是否可以作为协变量影响RL分布和排泄。方法:本研究为前瞻性队列研究。选择40例美国麻醉医师分级（ASA）I-II级，腹腔镜下择期胆囊切除术（胆囊炎组，n=20）或者腹腔镜下急诊阑尾切除术（阑尾炎组，n=20）。所有患者麻醉诱导前开始输注RL，按15 mL/kg，35 min内输毕。采用酶联免疫（enzyme-linked immunosorbent assay,ELISA）方法测定血浆炎症（TNF-α,IL-10和CRP）或者内皮损伤生物标记物（syndecan-1,SDC-1）；利用血红蛋白（Hb）稀释-时间曲线和尿量，使用Phoenix软件，采用非线性混合效应模型分析计算RL液体动力学参数和协变量的影响。结果:与胆囊炎组相比，阑尾炎组RL从组织间隙到血浆的转运速率常数（k21）显著降低（14×10-3min-1 versus 35×10-3min-1;P=0.012）。阑尾炎组C反应蛋白（CRP）升高［中位数38.1(1.8-143.6) μg/mL versus 1.3(0.1-159.0) μg/mL;P<0.001］；与清醒状态相比，麻醉期间（输液开始后30～45 min），液体从中央室中到外周室的转运速率常数（k12）显著增加（57×10-3min-1 versus 32×10-3min-1；P<0.01）。清除速率常数（k10）降低90%（0.6×10-3min-1 versus 5.3×10-3min-1;P<0.001）。无论在清醒状态还是麻醉状态下低血压均能降低液体清除；炎症或者内膜损伤的生物标记物不能作为显著影响RL液体动力学参数的协变量。结论:阑尾炎或者胆囊炎患者术前输入液体后“炎症反应的生物标记物”不是RL的液体动力学的协变量，但是两组患者中，全身麻醉期间输入液体的清除率下降。     

Microscopic examination of the microstructure and deformation of conventional and auxetic foams

Auxetic materials have a negative Poisson’s ratio, that is, they expand laterally when stretched longitudinally. One way of obtaining a negative Poisson’s ratio is by using a re-entrant cell structure. Auxetic foam was fabricated from a conventional polymeric foam. Assuming similar mechanical properties for the solid material comprising the foams, the principle variable affecting the properties of the foam is the geometry of the cells. This means that the unusual mechanical properties of auxetic foams are attributed to the deformation characteristics of re-entrant microstructures. In this paper, the results of optical- and scanning electron-microscopic studies of the geometrical parameters for the different foams examined are presented. Examples of the microstructural deformation mechanisms observed are also presented. Comparison between the conventional foams and their auxetic conversions are also made. This revised version was published online in November 2006 with corrections to the Cover Date.     

我公司进行热电联产的可行性分析

大压差减温减压是能的严重贬值。根据公司供热现状，分析了热电联产的可行性，利用蒸汽余压发电后，再供生产系统各热用户，这样既节约了能源又缓解了集团公司用电紧张的局面，而且有相当可观的经济效益。     

蜕变测试和断言检查的比较与实验研究

在软件测试中,测试预言是一种用于检查程序在测试中是否正常运行的机制.然而在某些实际情况下,还无法制定测试预言或者难以有效地应用测试预言.针对此类测试预言问题,蜕变测试于近年应运而生,但蜕变测试的效率问题还没有被充分地加以研究.作者用控制实验的方法研究了使用蜕变测试的成本及效率,进而将蜕变测试和常用的断言检查两种方法的错误检测率和时间成本进行了比较和分析.实验结果表明,相比于断言检查方法,蜕变测试具有检测到更多错误的潜力.通过分析蜕变测试的效率和性能,与断言测试相比,蜕变测试的错误检测率更高效而效率有待提高,可适用于较为粗粒度的测试需求.     

Discrete Adaptive Sliding Mode Control of a State-Space System with a Bounded Disturbance

This paper presents the discrete adaptive sliding mode control of a state-space system in the presence of a bounded disturbance. The delta form of the discrete state-space model is used as it closely resembles that of the continuous model. The control law takes into account of the effect of the disturbance by using its approximate value. The system behavior in the vicinity of the sliding surface is studied. It is shown that the adaptive controller leads to a stable closed-loop system. Also, simulation results are presented to illustrate the features of the proposed adaptive control strategy.     

An algorithm for function restoration using eigenvectors†

This paper presents an algorithm for the restoration of the characteristics of a function from a finite number of observed points. The algorithm uses the eigenvectors of the Gramian of the observed vectors and is based on the assumption that the function to be constructed can be represented by a specified form. Convergence of the algorithm is proved for the noiseless case. When noise is present, a bound for the error is obtained. For functions not representable in the assumed form, the algorithm can be used to test the non-representability of the function. A numerical example is given to illustrate the theoretical investigation.     

A note on the potential function algorithm for pattern classification†

A system design engineer often resorts to redundancies while maximizing the probability of success of a system designed to perform a certain job over a period, This will have to be done within the resources available. The problem of maximizing system reliability, subject to some linear constraints such as cost, weight or volume, is considered in this paper- The usual problem is transformed to a suitable form and the least square concept is used to develop a solution technique. This type of approach is found to be very simple and faster than earlier methods although the solution is an approximate one.     

Singular extremal control problem with time delay

In this article, the singular extremal control problem with time delay is studied from the viewpoint of the calculus of variation and matrix theory. Some sufficient conditions for the non-negativity of the second variation are obtained for an optimal control problem with a delayed state vector. The hypothesis of Hass is first assumed, and the total singular situation of Jacobson and Bell is also considered. A second-order necessary condition for optimality is also presented.     

A Modification of the Coates Gain Formula for the Analysis of Linear Systems

In this paper, the Coates flow-graph gain formula is modified by the introduction of the loop-set and the two-loop-set, baaed on the concepts of the tree and the two-tree in network topology. The analogy is evident by observing that the two-trees T _ij of a given graph G can be obtained by coalescing vertices i and j of G and thon removing the self-loops. In a similar manner, the two-loop-sets can be obtained from the flow graph by first modifying the graph and then obtaining the loop-sets of tho modified graph. Because of such modification, the derivation of tho gain formula is considerably simplified. Consequently, the evaluation of the terms in the formula becomes easier. Finally, a simple method of determining the number of terms in the formula is derived as a check against possible omission of terms due to carelessness.