首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   411986篇
  免费   7289篇
  国内免费   1782篇
电工技术   8064篇
综合类   1039篇
化学工业   58761篇
金属工艺   14607篇
机械仪表   12156篇
建筑科学   11827篇
矿业工程   1108篇
能源动力   11302篇
轻工业   43340篇
水利工程   3448篇
石油天然气   2062篇
武器工业   94篇
无线电   56050篇
一般工业技术   76432篇
冶金工业   75370篇
原子能技术   5662篇
自动化技术   39735篇
  2021年   2595篇
  2020年   2089篇
  2019年   2682篇
  2018年   4102篇
  2017年   4241篇
  2016年   4275篇
  2015年   3566篇
  2014年   6015篇
  2013年   19696篇
  2012年   10640篇
  2011年   15174篇
  2010年   11739篇
  2009年   13284篇
  2008年   14275篇
  2007年   14692篇
  2006年   13204篇
  2005年   12225篇
  2004年   11812篇
  2003年   11595篇
  2002年   10843篇
  2001年   10888篇
  2000年   9681篇
  1999年   10321篇
  1998年   23587篇
  1997年   17212篇
  1996年   13356篇
  1995年   10961篇
  1994年   9751篇
  1993年   9313篇
  1992年   7042篇
  1991年   6718篇
  1990年   6340篇
  1989年   6006篇
  1988年   5758篇
  1987年   4814篇
  1986年   4771篇
  1985年   5912篇
  1984年   5527篇
  1983年   4762篇
  1982年   4431篇
  1981年   4394篇
  1980年   4130篇
  1979年   4031篇
  1978年   3724篇
  1977年   4501篇
  1976年   6054篇
  1975年   3083篇
  1974年   2973篇
  1973年   2850篇
  1972年   2290篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Dense pressure-sintered reaction-bonded Si3N4 (PSRBSN) ceramics were obtained by a hot-press sintering method. Precursor Si powders were prepared with Eu2O3–MgO–Y2O3 sintering additive. The addition of Eu2O3–MgO–Y2O3 was shown to promote full nitridation of the Si powder. The nitrided Si3N4 particles had an equiaxial morphology, without whisker formation, after the Si powders doped with Eu2O3–MgO–Y2O3 were nitrided at 1400 °C for 2 h. After hot pressing, the relative density, Vickers hardness, flexural strength, and fracture toughness of the PSRBSN ceramics, with 5 wt% Eu2O3 doping, were 98.3 ± 0.2%, 17.8 ± 0.8 GPa, 697.0 ± 67.0 MPa, and 7.3 ± 0.3 MPa m1/2, respectively. The thermal conductivity was 73.6 ± 0.2 W m?1 K?1, significantly higher than the counterpart without Eu2O3 doping, or with ZrO2 doping by conventional methods.  相似文献   
2.
The influence of the microstructure on the corrosion rate of three monolithic SiC samples in FLiNaK salt at 900 °C for 250 h was studied. The SiC samples, labeled as SiC-1, SiC-2, and SiC-3, had corrosion rates of 0.137, 0.020, and 0.043 mg/cm2h, respectively. Compared with grain size and the presence of special grain boundaries (i.e., Σ3), the content of high-angle grain boundaries (HAGBs) appeared to have the strongest influence on the corrosion rate of SiC in FLiNaK salt, since the corrosion rate increased six times as the concentration of high-angle grain boundaries increased from 19 to 32% for SiC-2 and SiC-1, respectively. These results stress the importance of controlling the content of HAGBs during the production process of SiC.  相似文献   
3.
The main drawback of bioglasses is their restricted use in load bearing applications and the consequent need to develop stronger glassy materials. This has led to the consideration of oxynitride glasses for numerous biomedical applications. This paper investigated two different types of glasses at a constant cationic ratio, with and without nitrogen (a N containing and a N-free glass composition) to better understand the effect of N on the biological properties of glasses. The results revealed that the addition of N increased the glass transition temperature, isoelectric point (IEP) and slightly increased wettability. Moreover, compared to N including glass, N-free glass exhibited better anti-bacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), two key bacteria that infect implants. In summary, these in vitro results indicated that amine functional groups existing in N containing glasses which are missing in N-free glasses, caused a slight difference in wetting behavior and a more obvious change in isoelectric point and in bacterial response. N-free glasses exhibited better inhibitory results both against E. coli and S. aureus compared to N including glass suggesting that oxygen rich glasses should be further studied for their novel antibacterial properties.  相似文献   
4.
5.
6.
游宇  曹雪梅 《机械传动》2021,45(9):56-61,67
为提高弧齿锥齿轮传动系统的平稳性,研究了不同承载传动误差下齿轮振动特性的变化规律.以MASTA软件为工具,建立了弧齿锥齿轮传动系统的有限元模型,通过改变从动轮负载得到了不同的承载传动误差;以振动加速度瀑布图、振动加速度幅频谱以及噪声曲线图为对象,对比分析了不同负载下的齿轮振动特性.结果表明,当承载传动误差波动减小时,齿轮的振动噪声都会出现降低的趋势.分析结果为提高齿轮传动系统的平稳性提供了可靠依据.  相似文献   
7.
Inhibition of PSD-95 has emerged as a promising strategy for the treatment of ischemic stroke, as shown with peptide-based compounds that target the PDZ domains of PSD-95. In contrast, developing potent and drug-like small molecules against the PSD-95 PDZ domains has so far been unsuccessful. Here, we explore the druggability of the PSD-95 PDZ1-2 domain and use fragment screening to investigate if this protein is prone to binding small molecules. We screened 2500 fragments by fluorescence polarization (FP) and validated the hits by surface plasmon resonance (SPR), including an inhibition counter-test, and found four promising fragments. Three ligand efficient fragments were shown by 1H,15N HSQC NMR to bind in the small hydrophobic P0 pockets of PDZ1-2, and one of them underwent structure-activity relationship (SAR) studies. Overall, we demonstrate that fragment screening can successfully be applied to PDZ1-2 of PSD-95 and disclose novel fragments that can serve as starting points for optimization towards small-molecule PDZ domain inhibitors.  相似文献   
8.
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal disease with a 5-year survival rate of less than 10% following diagnosis. The aggressive and invasive properties of pancreatic cancer tumors coupled with poor diagnostic options contribute to the high mortality rate since most patients present with late-stage disease. Accordingly, PDAC is linked to the highest rate of cancer-associated venous thromboembolic disease of all solid tumor malignancies. However, in addition to promoting clot formation, recent studies suggest that the coagulation system in PDAC mediates a reciprocal relationship, whereby coagulation proteases and receptors promote PDAC tumor progression and dissemination. Here, upregulation of tissue factor (TF) by tumor cells can drive local generation of the central coagulation protease thrombin that promotes cell signaling activity through protease-activated receptors (PARs) expressed by both tumor cells and multiple stromal cell subsets. Moreover, the TF-thrombin-PAR1 signaling axis appears to be a major mechanism of cancer progression in general and PDAC in particular. Here, we summarize the current literature regarding the role of PAR1 in PDAC and review possibilities for pharmacologically targeting PAR1 as a PDAC therapeutic approach.  相似文献   
9.
Metal Science and Heat Treatment - The TRIP effect and deformation behavior of metastable austenitic steel were studied under tension in the temperatures range from –120 to +200°C. The...  相似文献   
10.
Metal organic frameworks (MOFs) containing zirconium secondary building units (SBUs) in UiO-67 and related MOFs, are highly active for neutralizing both the chemical warfare agents and simulants, such as dimethyl methylphosphonate (DMMP). However, two recent publications gave conflicting reports of DMMP reaction with UiO-67 under ultra high vacuum (UHV) conditions, with one reporting chemisorption and reaction (Wang et al., J Phys Chem C, 2017, 121, 11261–11272) and the other reporting only physisorption and reversible desorption (Ruffley et al., J Phys Chem C, 2019, 123, 19748–19758) from very similar temperature programmed desorption experiments. We show that the discrepancy between these experiments may be explained by different levels of missing linker defects in the UiO-67 samples. We present density functional theory calculations showing that SBU sites having two-adjacent missing linkers exhibit reaction barriers that are about 30 kJ/mol lower than SBU sites having a single missing linker. We also show that topology of the undercoordinated sites plays an important role in the reaction barrier under UHV conditions.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号