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实验性缺氧性肺动脉高压肺腺泡内动脉的超微结构观察 总被引:4,自引:0,他引:4
目的:观察实验性缺氧性肺动脉高压肺腺泡内动脉的超微结构变化并探讨其发生机理。方法:将Wistar大鼠随机分成对照组(n=9)及肺动脉高压组(n=9)。以右心导管法测定肺动脉平均压力(mPAP)。用透射电镜观察肺腺泡内动脉超微结构。结果:肺动脉高压组大鼠mPAP较对照组明显增高(P<0 01)。超微结构观察,肺动脉高压组大鼠肺腺泡内动脉内皮细胞增生、变性。内弹力膜厚薄不均。呼吸性细支气管水平小动脉中层平滑肌细胞增生;呼吸性细支气管水平及肺泡水平小动脉肌化。中间型细胞及血管周细胞增生。胶原原纤维增多。结论:肺腺泡内动脉平滑肌细胞增生及动脉肌化是缺氧性肺动脉高压特征性的超微结构变化。肺血管结构重建是缺氧性肺动脉高压形成的病理基础。 相似文献
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The densities, conductivities, and viscosities were measured for ternary solutions of N-hexyl, methylpyrrolidinium bromide ([PP1,6]Br)-N-butyl,methylpyrrolidinium bromide ([PP1,4]Br)-H2O and its binary subsystems [PP1,6]Br-H2O and [PP1,4]Br-H2O at (298.15, 303.15, 308.15, and 313.15) K, respectively. The results were used to test the predictability of the simple equations established for the prediction of density, conductivity, and viscosity of the mixed electrolyte solutions. The results show that the examined simple equations can offer good predictions for density, conductivity, and viscosity of the mixed ionic liquid solutions in terms of the corre-sponding properties of its binary subsystems of equal ionic strength. 相似文献
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