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1.
Degradation behaviour of aggregate particles of the size of railroad ballast (32–63 mm) is examined using Los Angeles (LA) milling and 3-D scanning techniques. Seven different rock types were tested at four stages of milling. For the analytical geometry and topography characterization, a new method based on Fourier and power spectra was used. The results are compared with those obtained using geometrical methods and traditional manual measurements. Diminishing of surface roughness and dimensions is evident. The change in roughness was 20–35% and for maximum dimensions of less than 10% in the case of hard rock types. The LA value was less than 15. For the weaker particles values of more than 40% and more than 20%, respectively, were obtained. The fractal dimension approached a value of 2 as a function of milling rates. Electronic Publication  相似文献   
2.
Persistent organic pollutants (POPs) encompass an array of anthropogenic organic and elemental substances and their degradation and metabolic byproducts that have been found in the tissues of exposed animals, especially POPs categorized as organohalogen contaminants (OHCs). OHCs have been of concern in the circumpolar arctic for decades. For example, as a consequence of bioaccumulation and in some cases biomagnification of legacy (e.g., chlorinated PCBs, DDTs and CHLs) and emerging (e.g., brominated flame retardants (BFRs) and in particular polybrominated diphenyl ethers (PBDEs) and perfluorinated compounds (PFCs) including perfluorooctane sulfonate (PFOS) and perfluorooctanic acid (PFOA) found in Arctic biota and humans. Of high concern are the potential biological effects of these contaminants in exposed Arctic wildlife and fish. As concluded in the last review in 2004 for the Arctic Monitoring and Assessment Program (AMAP) on the effects of POPs in Arctic wildlife, prior to 1997, biological effects data were minimal and insufficient at any level of biological organization. The present review summarizes recent studies on biological effects in relation to OHC exposure, and attempts to assess known tissue/body compartment concentration data in the context of possible threshold levels of effects to evaluate the risks. This review concentrates mainly on post-2002, new OHC effects data in Arctic wildlife and fish, and is largely based on recently available effects data for populations of several top trophic level species, including seabirds (e.g., glaucous gull (Larus hyperboreus)), polar bears (Ursus maritimus), polar (Arctic) fox (Vulpes lagopus), and Arctic charr (Salvelinus alpinus), as well as semi-captive studies on sled dogs (Canis familiaris). Regardless, there remains a dearth of data on true contaminant exposure, cause-effect relationships with respect to these contaminant exposures in Arctic wildlife and fish. Indications of exposure effects are largely based on correlations between biomarker endpoints (e.g., biochemical processes related to the immune and endocrine system, pathological changes in tissues and reproduction and development) and tissue residue levels of OHCs (e.g., PCBs, DDTs, CHLs, PBDEs and in a few cases perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonates (PFSAs)). Some exceptions include semi-field studies on comparative contaminant effects of control and exposed cohorts of captive Greenland sled dogs, and performance studies mimicking environmentally relevant PCB concentrations in Arctic charr. Recent tissue concentrations in several arctic marine mammal species and populations exceed a general threshold level of concern of 1 part-per-million (ppm), but a clear evidence of a POP/OHC-related stress in these populations remains to be confirmed. There remains minimal evidence that OHCs are having widespread effects on the health of Arctic organisms, with the possible exception of East Greenland and Svalbard polar bears and Svalbard glaucous gulls. However, the true (if any real) effects of POPs in Arctic wildlife have to be put into the context of other environmental, ecological and physiological stressors (both anthropogenic and natural) that render an overall complex picture. For instance, seasonal changes in food intake and corresponding cycles of fattening and emaciation seen in Arctic animals can modify contaminant tissue distribution and toxicokinetics (contaminant deposition, metabolism and depuration). Also, other factors, including impact of climate change (seasonal ice and temperature changes, and connection to food web changes, nutrition, etc. in exposed biota), disease, species invasion and the connection to disease resistance will impact toxicant exposure. Overall, further research and better understanding of POP/OHC impact on animal performance in Arctic biota are recommended. Regardless, it could be argued that Arctic wildlife and fish at the highest potential risk of POP/OHC exposure and mediated effects are East Greenland, Svalbard and (West and South) Hudson Bay polar bears, Alaskan and Northern Norway killer whales, several species of gulls and other seabirds from the Svalbard area, Northern Norway, East Greenland, the Kara Sea and/or the Canadian central high Arctic, East Greenland ringed seal and a few populations of Arctic charr and Greenland shark.  相似文献   
3.
Ove Ditlevsen   《Structural Safety》2003,25(2):165-191
This paper is partly tutorial by presenting well known classical decision theory in a slightly untraditional form, but it does also present thinking and results that have not been published in the engineering literature before. The paper introduces the mathematical modeling basis for rational formulation of decision criteria and public acceptance criteria connected to risk analysis of technical operations that may endanger human life and property. Public restrictions on the decisions concerning the design, construction and managing of the technical operation have in the past been imposed on the basis of the frequency and severity of experienced adverse events. No clear rationale to decide how restrictive the public should be in setting a boundary for allowable risk seems to have been applied. To clarify this problem, focus is on the difficulty of simultaneously having two decision makers, the owner that tries to optimize the net gain of the operation, and the public that has somewhat different preferences than the owner, but also strong interests in the success of the owner. The principles of rational decision are needed for appreciation of the problem. Recognizing that there is an insurance compensation value of a human life and a public money equivalent of a human life, where the last value usually is considerably larger than the first value, it is possible from the decision analysis to determine an upper limit that the public should impose on the ratio of the owner's expected loss rate to the expected gain rate. The public money equivalent of a human life is assessed by use of a recently in (Nathwani JS, Lind NC, Pandey MD. Affordable safety by choice: the life quality method. Waterloo, Ontario, Canada: Institute for risk Research, University of Waterloo, 1997) suggested Life Quality Index (LQI) that combines wealth in terms of Gross Domestic Product per person, life expectancy at birth, and yearly work time into a single number. The philosophy behind the published evaluations is that the prevention of a loss of a life is counteracted by a cost such that the LQI remains unchanged (Skjong R, Ronold K. Societal indicators and risk acceptance. In: 17th International Conference on Offshore Mechanics and Arctic Engineering, number OMAE98-1488. ASME; 1998; Rackwitz R. Optimization and risk acceptability based on the Life Quality Index. Structural Safety 2002;24:297–331.).  相似文献   
4.
To facilitate efficient drug delivery to tumor tissue, several nanomaterials have been designed, with combined diagnostic and therapeutic properties. In this work, we carried out fundamental in vitro and in vivo experiments to assess the labeling efficacy of our novel theranostic nanoprobe, consisting of glycogen conjugated with a red fluorescent probe and gadolinium. Microscopy and resazurin viability assays were used to study cell labeling and cell viability in human metastatic melanoma cell lines. Fluorescence lifetime correlation spectroscopy (FLCS) was done to investigate nanoprobe stability. Magnetic resonance imaging (MRI) was performed to study T1 relaxivity in vitro, and contrast enhancement in a subcutaneous in vivo tumor model. Efficient cell labeling was demonstrated, while cell viability, cell migration, and cell growth was not affected. FLCS showed that the nanoprobe did not degrade in blood plasma. MRI demonstrated that down to 750 cells/μL of labeled cells in agar phantoms could be detected. In vivo MRI showed that contrast enhancement in tumors was comparable between Omniscan contrast agent and the nanoprobe. In conclusion, we demonstrate for the first time that a non-toxic glycogen-based nanoprobe may effectively visualize tumor cells and tissue, and, in future experiments, we will investigate its therapeutic potential by conjugating therapeutic compounds to the nanoprobe.  相似文献   
5.
6.
The Clean Seas project focused on the role that existing Earth observing satellites might play in monitoring marine pollution. Results are presented here from August 1997, for the North Sea test site, using sea surface temperature (SST), colour and synthetic aperture radar (SAR) images in conjunction with a hydrodynamic model. There was good correlation between data sources, e.g. between SST and ERS-2 SAR images. Both datasets showed the development of fine plume structures close to the Rhine outflow, apparently associated with the outflow, and possibly caused by tidal pulsing of the Rhine Plume.

The model reproduced general temperature and sediment distributions well, but fine structures were not reproduced. Model sediment distribution patterns were verified using ‘chlorophyll concentration’ data from colour sensors, representative of sediment concentration in turbid water. In conjunction with the visible channels of the Advanced Very High Resolution Radiometer and Along-Track Scanning Radiometer, they give an uncalibrated measure of the sediment load. The model gives a more complete picture of the temporal dispersion of the Rhine Plume over time than is evident from the remotely sensed data alone.  相似文献   
7.
This study focuses on the statistical characterization of ice conditions (extent, sea ice occurrence probability (SIOP), and length of ice season) in the Gulf of Riga, Baltic Sea, using remote-sensing data. The optical remote-sensing data with 250 m resolution acquired by a Moderate Resolution Imaging Spectroradiometer (MODIS) during 2002–2011 were used for statistical characterization of sea ice. A method based on bimodal histogram analysis of remote-sensing reflectance data was developed to discriminate ice from water. In general, ice extent information obtained from MODIS data agrees with the official ice chart data (synthetic aperture radar (SAR) and in situ measurements) and multi-sensor product containing data from microwave and infrared instruments (R2 >0.83). However, in case of severe winters and extremely mild winters there are differences in the dates when maximum ice extent is registered. MODIS data can be used for detailed analysis of ice extent in specific basins of Baltic Sea. Depending on the year, the ice season length in the Gulf of Riga ranged from 68 to 146 days, and the maximum ice extent varied greatly from 329 to 15,350 km2. SIOP and number of ice days increased significantly in areas where the depth is less than 15 m. Based on negative-degree days and ice cover characteristics (SIOP and ice season length), three winter scenarios were defined: severe (2003, 2006, 2010, and 2011), medium (2004 and 2005), and mild (2007, 2008, and 2009).  相似文献   
8.
9.
The author describes the value analysis techniques applied in Scandinavian countries to promote new building methods, improve design and contracting procedures and provide better value for the client's money.

The topic forms part of the programme of CIB working group W55 on building economics, on which the author serves. He is head of the economics section of the Danish Building Research Institute.  相似文献   
10.
The Norwegian Energy Act that came into force in 1991 deregulated the electricity market and removed the former obligation power companies had to supply electricity to the geographical area they were responsible for. Hence producers can supply electricity on the basis of profitability. In 2007 the Energy Act was evaluated by the Government. As a part of this, a study concerning hydro reservoir handling before and after deregulation was carried out by SINTEF. Public statistics show that average hydro reservoir levels measured in per cent of reservoir capacity have been reduced after 1990. We have used the power-market model EMPS1 (EFI's Multi-area Power-market Simulator) to analyze if this reduction can be explained by natural variation in climatic variables or by structural changes that have occurred after 1990. Simulation results show that the reduced reservoir levels cannot be explained by natural variation in climatic variables. Structural changes such as increased transmission capacities can, however, explain some of the reduction. Our study does not indicate that the present reservoir handling gives reservoir levels that are too low. In this paper we also describe the stochastic dynamic optimization problem for long-term hydropower scheduling, and we explain how this problem actually is solved by the EMPS model.  相似文献   
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