Relationships between body condition,body condition loss,and serum metabolites during the transition period in primiparous and multiparous cows

In the transition period from late gestation to early lactation, dairy cows undergo tremendous metabolic changes. Insulin is a relevant antilipolytic factor. Decreasing serum concentrations of insulin and glucose, increasing serum concentrations of nonesterified fatty acids (NEFA) and β-hydroxybutyrate (BHB), and changes in body condition score (BCS) reflect the negative energy balance around calving. This study investigated peripartum metabolic adaptation in 359 primiparous and 235 multiparous German Holstein cows from a commercial dairy herd under field conditions. Body condition score was recorded and blood samples were taken 10 to 1 d prepartum, 2 to 4 d postpartum, and 12 to 20 d postpartum. Generalized mixed models and generalized estimation equations were applied to assess associations between prepartum BCS; BCS changes during the transition period; insulin, glucose, NEFA, and BHB serum concentrations; and milk yield, which was taken from an electronic milk meter from d 6 of lactation. Serum insulin concentrations of multiparous postpartum cows were lower compared with prepartum, and compared with primiparous cows. In general, primiparous cows had lower postpartum NEFA and BHB concentrations than multiparous cows. In primiparous cows, we identified a positive association between prepartum BCS and prepartum serum insulin concentration. Prepartum obese multiparous cows, but not primiparous cows, were characterized by higher postpartum serum NEFA and BHB concentrations and lower milk yield than other cows in the same parity class. Primiparous cows with a smaller degree of BCS loss during the transition period had higher postpartum insulin and lower NEFA concentrations and lower milk yield than other primiparous cows. In conclusion, primiparous cows had less lipolysis and lower milk yield than multiparous cows, associated with higher insulin concentrations. Avoiding high body condition loss during the transition period is a main factor in preventing peripartal metabolic imbalances of glucose and fat metabolism.     

Reinforced bending load‐stressed masonry – Suggestions for future designs / Bewehrtes biegedruckbeanspruchtes Mauerwerk – Vorschläge für zukünftige Bemessungen

European standardization bodies are currently working on the amendment to EN 1996‐1‐1, which will also affect the evaluation of reinforced masonry in Germany. For that reason, discussion suggestions are being made here for revisions to lay the groundwork for building materials evaluations and especially, evaluations of bending load‐stressed masonry walls or beams at their serviceability limit state (SLS) for load‐bearing capacities. Information already presented in E DIN 1053‐3:2008‐03 [N3] is being incorporated as well. Characteristic values for the compressive strength of the masonry parallel to the bed joints f_k,∥ are essential for the design of reinforced masonry, although they are currently not included in national application documents for Germany. For the time being, they can be mathematically calculated using conversion factors for the characteristic compressive strength values vertical to the bed joints f_k or by using the declared axial compressive strengths of the masonry units. The ultimate strains for masonry in general should be set consistently at ?_mu = ∣–0.002∣ as several masonry types do not exhibit higher compressive strain values. The use of steel strains higher than ?_su = 0.005 does not change any measurement results. Varying stress‐strain curves of the constitutive equations on masonry under compressive strain (parabolic, parabolic‐rectangular, tension block) lead to differing values of recordable bending moments despite having the same mechanical reinforcement percentage at higher normal forces. Therefore, clear guidelines should be made for the type of applicable constitutive equation for masonry walls under compressive strain. With the introduction of a tension block, the number values of the reduction factors λ for the compression zone height x, which is dependent on limit strains, and where applicable, reduced compressive strength, need to be determined, as with reinforced concrete construction. A modification of the bending moment based on the second order theory according to [N4] is presented for the calculation of reinforced masonry walls in danger of buckling. The use of reduction factors for the load capacity of the masonry cross section, such as for unreinforced masonry, does not appear to be appropriate as buckling safety evidence because here, the design task is the determination of a required reinforcement cross section.     

New insights into the association between lameness,behavior, and performance in Simmental cows

In a herd of 100 milking Simmental cows, data of performance and behavior parameters were collected automatically with different systems such as pedometers, an automatic milking system, and automatic weighing troughs for 1 yr. Performance measures were several milking-related parameters, live weight, as well as feed intake. Behavior-associated measures were feeding behavior (e.g. feeding duration, number of visits to the trough, and feeding pace) as well as activity such as lying duration, number of lying bouts, and overall activity. In the same time, lameness status of every cow was assessed with weekly locomotion scoring. According to the score animals were then classified lame (score 4 or 5) or nonlame (score 1, 2, or 3). From these data in total, 25 parameters summarized to daily values were evaluated for their ability to determine the lameness status of a cow. Data were analyzed with a regularized regression method called elastic net with the outcome lame or nonlame. The final model had a high prediction accuracy with an area under the curve of 0.91 [95% confidence interval (CI) = 0.88–0.94]. Specificity was 0.81 (95% CI = 0.73–0.85) and sensitivity was 0.94 (95% CI = 0.88–1.00). The most important factors associated with a cow being lame were number of meals, average feed intake per meal, and average duration of a meal. Lame cows fed in fewer and shorter meals with a decreased intake per meal. Milk yield and lying-behavior-associated parameters were relevant in the model, too, but only as parts of interaction terms demonstrating their strong dependence on other factors. A higher milk yield only resulted in higher risk of being lame if feed intake was decreased. The same accounts for lying duration: only if lying time was below the 50% quantile did an increased milk yield result in a higher risk of being lame. The association of lameness and daily lying duration was influenced by daily feeding duration and feeding duration at daytime. The results of the study give deeper insights on how the association between behavior and performance parameters and lameness is influenced by intrinsic factors in particular and that many of these have to be considered when trying to predict lameness based on such data. The findings lead to a better understanding why, for instance, lying duration or milk yield seem to be highly correlated with lameness in cows but still have not been overly useful as parameters in other lameness detection models.     

Material Transfer Inside Head Disk Interface for Heat Assisted Magnetic Recording

Heat assisted magnetic recording (HAMR) promises to deliver higher storage areal density than the current perpendicular magnetic recording products. Laser heating is implemented in HAMR to achieve magnetic writing of the very high coercivity media. However, the high temperature environment creates several reliability challenges for the head disk interface (HDI). In this paper, material transfer within the HDI under HAMR recording conditions is studied. The mechanisms of material transfer are explored via experiments and modeling. This study revealed that temperature difference and mechanical interaction between the head and media are the main mechanisms for material transfer inside the HDI. Possible methods to remove the material are also discussed in this paper.     

Space charge field effect on light emitting from tetracene field-effect transistor under AC electric field

By applying square wave AC voltage to the Au source electrode of tetracene based field-effect transistor (FET), electroluminescence (EL) was obtained. The results suggest that electrons and holes were injected alternately from the source electrode and recombined each other, and lead to the EL. This type of EL was localized at the interface between the source electrode and tetracene, and enhanced periodically with two relaxation times in accordance with the applied AC voltage cycle. We modeled the carrier behavior in the FET and explained the decay of EL, taking into account the space charge field contribution. Finally, using an AC voltage superposed on DC bias voltage, it was shown that electron injection was prompted only by space charge field.     

Activation Enthalpies of Deformation-Induced Lattice Defects in Severe Plastic Deformation Nanometals Measured by Differential Scanning Calorimetry

Samples of 99.99 pct pure copper and nickel of 99.998 pct purity were deformed by high-pressure torsion (HPT) at different hydrostatic pressures, to different shear strains. Activation enthalpies (Q) were determined by differential scanning calorimetry (DSC) using Kissinger’s method. For the one annealing peak found in HPT Cu, Q amounts to Q = 0.78 to 0.48 eV depending on the shear strain applied. In the case of Ni, the activation enthalpies of the two annealing peaks were determined as Q = 0.65 eV and Q = 0.95 eV, respectively, with no obvious dependence on shear strain, although this has been indicated by the annealing peak temperatures. Applying defect specific analyses of the annealing peaks, it turned out that the larger Q value represents the annihilation of dislocations and agglomerates, while the smaller one reflects the annihilation of single or double vacancies. Concerning the strain dependence of the larger Q, two possible explanations have been discussed: (1) the annihilation of dislocations assisted by the strain-dependent density of vacancy agglomerates and (2) the annihilation of dislocations enhanced by a strain-dependent level of long-range internal stresses. Because of closer correlations of Q with external and internal stresses at very high shear strains, explanation (2) has been favored.     

伦敦帕丁顿中心Two Kingdom Street项目

<正>KPF设计师事务所已完成了Two Kingdom Street项目设计。该项目投资8800万英镑,由Development Securities公司开发,为Aviva Investors公司和Quinlan Private公司所有。该项目提供了2.2万m2的最佳办公空间,是帕丁顿中心项目第二阶段的最新增加项目,位于帕丁顿火车站附近的大型综合开发区内。