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排序方式: 共有311条查询结果,搜索用时 15 毫秒
1.
Dr. Mimouna Madaoui Dr. Olivier Vidal Albert Meyer Mathieu Noël Prof. Dr. Jean-Marie Lacroix Dr. Jean-Jacques Vasseur Prof. Dr. Alberto Marra Dr. François Morvan 《Chembiochem : a European journal of chemical biology》2020,21(23):3433-3448
Galacto- and fuco-clusters conjugated with one to three catechol or hydroxamate motifs were synthesised to target LecA and LecB lectins of Pseudomonas aeruginosa (PA) localised in the outer membrane and inside the bacterium. The resulting glycocluster–pseudosiderophore conjugates were evaluated as Trojan horses to cross the outer membrane of PA by iron transport. The data suggest that glycoclusters with catechol moieties are able to hijack the iron transport, whereas those with hydroxamates showed strong nonspecific interactions. Mono- and tricatechol galactoclusters ( G1C and G3C ) were evaluated as inhibitors of infection by PA in comparison with the free galactocluster ( G0 ). All of them exhibited an inhibitory effect between 46 to 75 % at 100 μM, with a higher potency than G0 . This result shows that LecA localised in the outer membrane of PA is involved in the infection mechanism. 相似文献
2.
Lucas Jégo Daniel Milési Jean-Jacques Robin Christine Joly-Duhamel 《Polymer Engineering and Science》2020,60(1):95-103
The photocrosslinking of thick samples of 5-ethylidene-2-norbornene–ethylene propylene diene monomer (ENB-EPDM) under air at room temperature was investigated. First, a model study was carried out on low-molecular weight oligomers: squalene, 1,2-polybutadiene, and 1,4-polybutadiene. Several crosslinking agents (meth(acrylics), bismaleimide, and thiol) combined with various photoinitiators were tested to improve the reactivity of these oligomers under UV irradiation. Gel contents, crosslinking densities, viscosities, and viscoelastic properties were measured in order to characterize the extent of crosslinking. Acrylate-based crosslinking agents appeared to be the most reactive species and these results were then applied to a low-molecular weight EPDM. Several photoinitiators were tested and benzophenone turned out to be the most efficient photoinitiator when combined with trimethylolpropane triacrylate. Finally, a commercial EPDM was subsequently photocrosslinked and high gel content and crosslinking density were obtained after only 2 min of irradiation. POLYM. ENG. SCI., 60:95–103, 2020. © 2019 Society of Plastics Engineers 相似文献
3.
Ahmad Ahmadi Daryakenari Behrooz Mosallanejad Erfan Zare Mohammad Ahmadi Daryakenari Arash Montazeri Aleksandra Apostoluk Jean-Jacques Delaunay 《International Journal of Hydrogen Energy》2021,46(10):7263-7283
Electrophoretic deposition (EPD) is a versatile technique that has drawn attention due to its ease of use and performance in depositing high-quality layers at room temperature. This technique principle is based on the deposition of charged particles from a stable colloidal suspension on a conductive substrate using either a direct or alternating current. Using relatively simple and low-cost equipment, the EPD technique enables the deposition of layers with controlled microstructures at nanoscale. The EPD technique has been particularly successful in the fabrication of the electrocatalyst layers for low-temperature fuel cells, which are anchored on the top of the fuel cell electrodes. In comparison with other electrocatalyst layer deposition techniques such as drop-casting, the EPD technique offers clear advantages for the control of the thickness and packing density of the electrocatalyst layers. Owing to the dense packing density, electrocatalyst layers deposited by EPD could achieve enhanced conductivity and efficiency. The present review aims at comprehensively evaluating the recently published results on the electrocatalyst layers fabricated by EPD and applied in oxygen reduction reactions, alcohol electro-oxidation reactions, hydrogen evolution reactions, and oxygen evolution reactions. 相似文献
4.
Role of shear stress on composition, diversity and dynamics of biofilm bacterial communities 总被引:1,自引:0,他引:1
This article evaluates the effect of shear stress on the composition of biofilm bacterial communities. For the first time, a Conical Couette-Taylor Reactor (CCTR) was used to develop biofilms at varying shear stresses (from 0.055 to 0.27 Pa) and provided a useful model for studying the effect of hydrodynamics on biofilms. The composition, diversity and dynamics of biofilm bacterial communities were analysed using the PCR-SSCP fingerprint method. Results clearly demonstrate a link between shear stress and composition of the microbial communities. High shear stresses decrease biofilm diversity and the analysis of biofilm community dynamics suggests that shear stress would slow down biofilm maturation and tend to maintain a young biofilm. 相似文献
5.
6.
Sofiane Aloui Nicolas Delaunay Eric Kerherve Nathalie Deltimple Robert Plana Didier Belot 《Analog Integrated Circuits and Signal Processing》2012,70(2):203-211
A millimeter-wave Power Amplifier (PA) based on a 65nm CMOS technology from STMicroelectronics has been designed. The targeted
feature is the unlicensed band around 60 GHz suitable for wireless personal area network application (WPAN). To optimize the
linearity, the PA is designed under class A biasing to have an output compression point (OCP1) close to its saturated Power (P
sat). S-parameters and large signal measurement results are demonstrated and compared with electromagnetic simulations. The PA
offers a P
sat of 8.3 dBm, an OCP1 of 6 dBm and a gain of 6.7 dB. The die area is 0.29 mm2 with pads. Considering those results, one-tone simulations are not sufficient to characterize the linearity performances
of the PA in its real conditions of use. Consequently, two-tone simulations are firstly performed. After, linearity figures
of merit (FoM) are discussed applying an orthogonal frequency-division multiplexing (OFDM) modulated signal. The PA offers
an adjacent channel power ratio (ACPR) of 15 dB and an error vector magnitude (EVM) of 20% at PA compression operating mode. 相似文献
7.
F. Javier Fuentes Vincent Trouvé Emily Blessing Jean-Jacques Cordier Jens Reich 《Fusion Engineering and Design》2013,88(6-8):597-601
The optimization of the manufacturing/assembly tolerances and processes in ITER Experimental Nuclear Fusion Device is one of the key tasks to optimize the fabrication cost, to prevent problems during assembly and to ensure that the critical homogeneity of the magnetic field and the positioning requirements of the plasma facing components can be achieved. This task is further complicated by the strong interplay among the various Tokamak systems, as for instance in the inner region of the machine where the clearances between Central Solenoid, Toroidal Field Coils, Thermal Shield, Vacuum Vessel and In-Vessel components have been minimized for their large influence on the magnetic flux and the overall machine cost.A 3D tolerance simulation analysis of ITER Tokamak machine has been developed based on 3DCS dedicated software. The dimensional variation model is representative of Tokamak functional tolerances and processes, predicting accurate values for the amount of variation on critical areas. In addition, dimensional simulations help to determine the key tolerances that contribute to a particular variation.This paper describes the current status of the Tokamak dimensional variation studies and its management plan, highlighting the status of compliance of allocated tolerances with input requirements. Management of risk issues and corrective actions are also described. 相似文献
8.
Christian J. Cyron Jean-Jacques Marigo Paul Sicsic 《International Journal of Fracture》2014,187(1):51-75
This paper studies the initiation of cohesive cracks in the thermal shock problem through a variational analysis. A two-dimensional semi-infinite slab with an imposed temperature drop on its free surface is considered. Assuming that cracks are periodically distributed and orthogonal to the surface, at short times we show that the optimum is a distribution of infinitely close cohesive cracks. This leads us to introduce a homogenized effective behavior which reveals to be stable for small times, thanks to the irreversibility. At a given loading cracks with a non-cohesive part nucleate. We characterize the periodic array of these macro-cracks between which the micro-cracks remain. Finally, for longer times, the cohesive behavior converges towards that from Griffith’s evolution law. Numerical investigations complete and quantify the analytical results. 相似文献
9.
Subrata Panda Jean-Jacques Fundenberger Yajun Zhao Jianxin Zou Laszlo S. Toth Thierry Grosdidier 《International Journal of Hydrogen Energy》2017,42(35):22438-22448
While severe plastic deformation (SPD) on bulk samples has been widely applied for modifying the H-sorption properties, there has been little attention towards the use of SPD on powder materials. In this context, the aim of the present work was to compare the H-storage properties of high-pressure torsion (HPT) consolidated products obtained from two distinct Mg powder precursors: atomized micro-sized and condensed ultrafine powder particles. The results showed that the nature of the initial powder precursor had a pronounced effect on the H-sorption behavior. The HPT product obtained from the condensed ultrafine powder showed faster absorption kinetics than the consolidated product obtained from the atomized powder. However, the HPT product obtained from atomized powder could absorb more hydrogen and showed faster desorption kinetics corresponding to a lower activation energy. These results are discussed by taking into account the effectiveness of the HPT process to refine the grain sizes and differences in the dispersion of fine MgO oxide particles. 相似文献
10.
Delaunay P.-Y. Binh Minh Nguyen Hoffman D. Huang E.K.-W. Razeghi M. 《Quantum Electronics, IEEE Journal of》2009,45(2):157-162
The recent introduction of a M-structure design improved both the dark current and R0 A performances of type-II InAs-GaSb photodiodes. A focal plane array fabricated with this design was characterized at 81 K. The dark current of individual pixels was measured between 1.1 and 1.6 nA, 7 times lower than previous superlattice FPAs. This led to a higher dynamic range and longer integration times. The quantum efficiency of detectors without antireflective coating was 74%. The noise equivalent temperature difference reached 23 mK, limited only by the performance of the testing system and the read out integrated circuit. Background limited performances were demonstrated at 81 K for a 300 K background. 相似文献