Systematics study through scanning electron microscopy; a tool for the authentication of herbal drug Mentha suaveolens Ehrh

In all over the world, herbal drugs are usually adulterated with similar species or varieties due to incorrect identification. Most of herbal products devoid purity and quality, therefore an attempt was carried out to identify plant species and authenticate its herbal drug products from Mentha suaveolens. Microscopy tools provide an excellent platform to identify plants at species level. In this study, microscopic and pharmacokinetic parameters of M. suaveolens were observed. Plant species were collected from high diverse areas of Northern Pakistan. Macro and micro‐morphology including palynology and anatomical features were analyzed to study M. suaveolens. Species characteristics were studied, while implementing microscopic techniques for the delimitation and identification of the species. Traditionally Mentha species are used to cure several diseases that is, digestive disorders, respiratory disorders. Micromorphology (stem, leaves, flowers structure, length etc.), palynology (shape, size of pollen etc.), and anatomical characters (types of stomata, epidermal cell shape, and trichomes) were studied. Micromorphology and anatomical characters were of great interest and significance to discuss the taxonomy of the species. Taxonomic characters were studied to characterize and authenticate the species. The aim of the present study is to observe in detail the taxonomic identification of the species in term of morphology, palynology, and foliar epidermal anatomy for the correct identification along with their medicinal uses in the area.     

Phytoplankton primary production, chlorophyll-a and nutrient concentrations in the water column of mountainous Lake Phewa, Nepal

The seasonal patterns of phytoplankton primary production, chlorophyll‐a concentration, cell number and several other limnological variables in Lake Phewa, located in the active monsoon zone in Central Himalaya, Nepal, were studied for a year beginning in April 2001. During the study period, the gross primary production and chlorophyll‐a concentrations were relatively low during the monsoon season. The phytoplankton cell number, represented by 24 genera, also fluctuated seasonally, but tended to increase in the pre‐ and post‐monsoon period. These results suggest that the monsoon plays a crucial role in the primary production and phytoplankton dynamics for Lake Phewa. Among the phytoplankton species, Microcystis aeruginosa, a representative species for eutrophic lakes, was the dominant phytoplankton. At the same time, however, it is clear that the lake is not yet heavily eutrophic. The present study suggests that the exchange of lake water during the monsoon season contributes to maintaining the health of the lake against further degradation. Nevertheless, the silt carried in the monsoon rain run‐off from the lake's catchment area suggests increasingly serious degradation problems for this small mountainous lake.     

Synthesis and characterization of biocompatible hydroxyapatite coated ferrite

Ferrite particles coated with biocompatible phases can be used for hyperthermia treatment of cancer. We have synthesized substituted calcium hexaferrite, which is not stable on its own but is stabilized with small substitution of La. Hexaferrite of chemical composition (CaO)_0.75(La₂0₃)_0.20(Fe₂O₃)₆ was prepared using citrate gel method. Hydroxyapatite was prepared by precipitating it from aqueous solution of Ca(NO₃)₂ and (NH₄)₂HPO₄ maintaining pH above 11. Four different methods were used for coating of hydroxyapatite on ferrite particles. SEM with EDX and X-ray diffraction analysis shows clear evidence of coating of hydroxyapatite on ferrite particles. These coated ferrite particles exhibited coercive field up to 2 kOe, which could be made useful for hysteresis heating in hyperthermia. Studies by culturing BHK-21 cells and WBC over the samples show evidence of biocompatibility. SEM micrographs and cell counts give clear indication of cell growth on the surface of the sample. Finally coated ferrite particle was implanted in Kasaulli mouse to test its biocompatibility. The magnetic properties and biocompatibility studies show that these hydroxyapatite coated ferrites could be useful for hyperthermia.     

Restoration of small lakes through cooperative management: A suitable strategy for poverty‐laden areas in developing countries?

Lake Rupa is a small, subtropical, shallow lake with a surface area of 100 ha situated 600 m a.s.l. in Central Himalaya, Nepal. This degraded lake was studied between 2000 and 2006, with the goal of determining whether or not it could be restored by a community‐based cooperative of local people living in its catchment. Main threats to the lake, its aquatic life and its very existence include encroachment by excessive aquatic vegetation, sedimentation, and low in‐lake concentrations of dissolved oxygen (DO). Small lakes (≤ 500 ha) are relatively prone to the process of ‘succession and climax’, although they also can be of social, environmental and ecological importance. Thus, their disappearance could spark social chaos and disorder in areas already having to cope with other rapid environmental changes. This means that credible mechanisms for revitalizing or protecting small lakes are an important goal. Accordingly, a lake cooperative of 329 households living in close vicinity to Lake Rupa was formed in 2002, by prioritizing traditional fishers, women and other deprived community members with the goals of respecting the citizenry and equity. Following the cooperative's campaigns directed at weed removal and fish stocking, encroachment of vegetation on the lake margins was halted, its aquatic weeds became under control, and its fisheries improved. In addition to the cooperative's restoration activities, several water quality parameters, including water transparency and DO and chlorophyll‐a concentrations, were monitored on a monthly basis. The measured water transparency was inconsistent, exhibiting large variations between 2000 and 2003. Relatively low, but consistent, values, however, were measured after 2004. The results imply that the removal of weeds, and sufficient nutrients and solar radiation are subsequently available to the lake's phytoplankton communities. Supporting this notion is that the chlorophyll‐a concentration spiked to 205 µg L⁻¹ in November 2006, the water transparency became consistent, and the DO concentration increased to >3.8 mg L⁻¹ during the critical months (March–May) after 2004. These water quality indicators indicated improvement in the degraded Lake Rupa, suggesting that the establishment of cooperatives such as that highlighted in this study could be a powerful and sustainable mechanism for restoring degraded lakes in similar socioeconomic settings by maintaining equity, by connecting communities with their resources, and by facilitating integrity, equity, citizenry and social justice.     

Intermetallic phases in Al-Mn alloys

The intermetallic phases present in high-purity and commercial purity Al-Mn alloys (up to 2% Mn) in as-cast and heat-treated conditions were extracted electrolytically in 10% HCl in methanol solution and identified by X-ray diffraction. As iron is known to increase the coarse cast-intermetallic particles and to cause refinement of the grain size after recrystallization, different amounts of iron (up to 0.5%) were added and the resulting intermetallic phases were extracted and identified with and without heat treatment. The unidentified phase -Al (Mn, Fe)Si, reported by Sperry and others, was recognized as corresponding for ASTM card number 6-0669 and the conditions favourable for its formation were determined. This phase may be responsible for refining the grain size after recrystallization in commercial purity alloys as compared to high-purity Al-Mn alloys and may therefore be tried as an inoculant (by adding powdered compound to liquid alloys) for grain refining.     

The Double Edge Sword Based Distributed Executor Service

Scalability is one of the most important quality attribute of software-intensive systems, because it maintains an effective performance parallel to the large fluctuating and sometimes unpredictable workload. In order to achieve scalability, thread pool system (TPS) (which is also known as executor service) has been used extensively as a middleware service in software-intensive systems. TPS optimization is a challenging problem that determines the optimal size of thread pool dynamically on runtime. In case of distributed-TPS (DTPS), another issue is the load balancing b/w available set of TPSs running at backend servers. Existing DTPSs are overloaded either due to an inappropriate TPS optimization strategy at backend servers or improper load balancing scheme that cannot quickly recover an overload. Consequently, the performance of software-intensive system is suffered. Thus, in this paper, we propose a new DTPS that follows the collaborative round robin load balancing that has the effect of a double-edge sword. On the one hand, it effectively performs the load balancing (in case of overload situation) among available TPSs by a fast overload recovery procedure that decelerates the load on the overloaded TPSs up to their capacities and shifts the remaining load towards other gracefully running TPSs. And on the other hand, its robust load deceleration technique which is applied to an overloaded TPS sets an appropriate upper bound of thread pool size, because the pool size in each TPS is kept equal to the request rate on it, hence dynamically optimizes TPS. We evaluated the results of the proposed system against state of the art DTPSs by a client-server based simulator and found that our system outperformed by sustaining smaller response times.     

Urban growth modeling of Kathmandu metropolitan region, Nepal

The complexity of urban system requires integrated tools and techniques to understand the spatial process of urban development and project the future scenarios. This research aims to simulate urban growth patterns in Kathmandu metropolitan region in Nepal. The region, surrounded by complex mountainous terrain, has very limited land resources for new developments. As similar to many cities of the developing world, it has been facing rapid population growth and daunting environmental problems. Three time series land use maps in a fine-scale (30 m resolution), derived from satellite remote sensing, for the last three decades of the 20th century were used to clarify the spatial process of urbanization. Based on the historical experiences of the land use transitions, we adopted weight of evidence method integrated in cellular automata framework for predicting the future spatial patterns of urban growth. We extrapolated urban development patterns to 2010 and 2020 under the current scenario across the metropolitan region. Depending on local characteristics and land cover transition rates, this model produced noticeable spatial pattern of changes in the region. Based on the extrapolated spatial patterns, the urban development in the Kathmandu valley will continue through both in-filling in existing urban areas and outward rapid expansion toward the east and south directions. Overall development will be greatly affected by the existing urban space, transportation network, and topographic complexity.     

Effect of a magnetic field on the specific heat jump of a superconducting alloy containing paramagnetic impurities with local states within the gap

The effect of a uniform magnetic field on the specific heat jump \({\Delta C}\) of a superconductor containing paramagnetic impurities has been investigated. The impurities are described by the Shiba-Rusinov model. Taking the normalized position of the bound state within the BCS gap ε₀=0.8 and 0.0 and the parameter α(=〈S _z ² 〉/S²)=1.0 and 1/3 as typical values, we find the detailed dependence of \({\Delta C}\) on the impurity concentration \(\bar c\) and the transition temperature T_c. In some cases \({\Delta C}\) diverges at certain values of \(\bar c\) or T_c, signaling a change of the normal-superconductor phase transition from second order to first order.     

Nano and micro structural studies of thin films of ZnO

Zinc oxide thin films grown by sol–gel and RF sputtering methods have been characterized. The characterization techniques used involve ellipsometry, optical absorption, scanning tunneling microscopy, scanning and transmission electron microscopy. The films grown by sol–gel spin method which followed zinc acetate route exhibited a smoother texture than the films, which were deposited by using zinc nitrate route. The later type of films showed a dendritic character. Nano-structured fine grains of size ranging from 20 to 60 nm were observed with zinc nitrate precursor film. Individual grains show a sharp contrast with different facets and boundaries. Crystal planes and lattice parameters calculated by electron diffraction and X-ray diffraction are quite close and in agreement with the reported values in literature. Scanning tunneling microscopy has been used for measuring the average roughness of the surface and estimating the lattice constants. The STM studies of RF sputtered films, although showing a ZnO structure, exhibited a disturbed lattice. This was presumably due to the fact that after deposition the films were not annealed. Nanographs of 2D and 3D view of atomic positions of ZnO have been presented by using scanning tunneling microscopy.     

Conductometric Study of Some Metal Halides in Glycerol + Water Mixtures

Electrolytic conductivities of potassium halides, KX (X = Cl⁻, Br⁻, I⁻) have been investigated in 10, 20, and 30 mass% glycerol + H₂O mixtures at 298.0, 308.0, and 318.0 K. The conductance data have been analyzed by the Fuoss-conductance–concentration equation in terms of the limiting molar conductance (Λ⁰), the association constant (K _A ), and the distance of closest approach of ion (R). The association constant (K _A ) tends to increase in the order: 10 mass% < 20 mass% < 30 mass% glycerol + water mixtures, while it decreases with temperature. Thermodynamic parameters ΔH ⁰, ΔG ⁰, and ΔS ⁰ are obtained and discussed. Also, Walden products (Λ⁰η) are reported. The results have been interpreted in terms of ion–solvent interactions and structural changes in the mixed solvents.