Improved Yen-Joye's authenticated multiple-key agreement protocol

An authenticated multiple-key agreement protocol is proposed. The protocol is not only secure against the unknown-key attack but also more efficient than other protocols.     

The investigation of 32P wire for catheter-based endovascular irradiation

The dose distribution from a 32P source has been measured and calculated in order to evaluate its application in endovascular irradiation. The source dimension was 27 mm in length and 0.3 mm in diameter and was embedded in the end of a Ni-Ti wire. Dose measurements were performed using radiochromic film in several specially designed tissue equivalent phantoms. Loevinger's point dose kernel was used for the calculation. The approximate dose rate at a radial distance of 1.5 mm from the center of the source was found to be 6.75 cGy/s per GBq (0.25 cGy/s per mCi), which allows the delivery of a therapeutic dose in a short time interval with a satisfactory homogeneity without stepping the source. However, the dose rate falls off almost exponentially along the radial distance. Therefore it may not be suitable for treating large diameter vessel from a centrally located source. The effect of a curved 32P wire source on the radial dose distribution was also investigated. The results showed that for a maximum bend of 180 degrees the dose rate was increased by as much as 20% along the inner radial distance but decreased by as much as 20% along the outer radial distance compared to the dose along a straight wire. However, for curvatures normally encountered in a clinical situation, the dose rate was changed less than 5%.     

Challenges in computer architecture evaluation

We focus on problems suited to the current evaluation infrastructure. The current limitation and trends in evaluation techniques are troublesome and could noticeably slow the rate of computer system innovation. New research has been recommended to help and make quantitative evaluations of computer systems manageable. We support research in the areas of simulation frameworks, benchmarking methodologies, analytic methods, and validation techniques.     

A novel integration approach for combining the components to minimize a micro-fuel cell

This work employs porous silicon as a gas diffusion layer (GDL) in a micro-fuel cell. Pt catalyst is deposited on the surface of, and inside, the porous silicon by the physical vapor deposition (PVD) method, to improve the porous silicon conductivity. Porous silicon with Pt catalyst replaces traditional GDL, and the Pt metal that remains on the rib is used to form a micro-thermal sensor in a single lithographic process.     

Parametric study of the electrical to thermal power conversion in an inductively coupledrf plasma torch

An inductively coupled (ic) radio-frequency (rf) stabilized argon plasma was generated in a quartz tube using a 7 MHzrf generator. The electrical and thermal powers were measured and the efficiency of energy conversion was computed. The results indicate that for a constant power input, there is an optimum argon flow rate for which maximum energy conversion efficiency occurs.     

Copper coating on carbon fibres and their composites with aluminium matrix

A uniform and continuous coating of copper was given to carbon fibres by cementation or electroless techniques. In both cases, when coating thicknesses were less than 0.2 m, copper deposition was discontinuous over the fibres, and above 0.2 m, coatings were continuous. In electroless coating, about 75% of the continuously coated fibres had a coating thickness range 0.2–0.5 m and above this showed isolated dendrite deposits of copper. In the cementation process, about 75% of the continuously coated fibres had a coating thickness range 0.2–0.6 m, and above this thickness, fine crystallite-type copper deposition was found over smoothly coated copper. The ultimate tensile strength of continuously electroless-coated fibres were nearer to the uncoated fibres, suggesting defect-free coating, while fibres coated by the cementation process exhibited lower ultimate tensile strength values. The tensile fracture of both electroless- and cementation-coated fibres showed delamination of the coating, suggesting poor bonding between coating and the fibre. In composites, prepared by dispersing the coated chopped fibres in a pure aluminium matrix, uniform and random distribution of the fibres were observed without appreciable fibre-metal interaction. The CuAl₂ intermetallics were largely found in the matrix and only very small amounts were observed at fibre/matrix interfaces. Additions of about 2 wt% Mg to the matrix prior to the fibre dispersion did not appreciably change the distribution pattern of the fibres, but in addition to CuAl₂ phase, Mg₂Si phases were observed in the matrix as well as at the interface.     

The Antithrombotic Agent Pterostilbene Interferes with Integrin αIIbβ3-Mediated Inside-Out and Outside-In Signals in Human Platelets

Platelets play a crucial role in the physiology of primary hemostasis and pathological processes such as arterial thrombosis; thus, developing a therapeutic target that prevents platelet activation can reduce arterial thrombosis. Pterostilbene (PTE) has remarkable pharmacological activities, including anticancer and neuroprotection. Few studies have reported the effects of pterostilbene on platelet activation. Thus, we examined the inhibitory mechanisms of pterostilbene in human platelets and its role in vascular thrombosis prevention in mice. At low concentrations (2–8 μM), pterostilbene strongly inhibited collagen-induced platelet aggregation. Furthermore, pterostilbene markedly diminished Lyn, Fyn, and Syk phosphorylation and hydroxyl radical formation stimulated by collagen. Moreover, PTE directly hindered integrin α_IIbβ₃ activation through interfering with PAC-1 binding stimulated by collagen. In addition, pterostilbene affected integrin α_IIbβ₃-mediated outside-in signaling, such as integrin β₃, Src, and FAK phosphorylation, and reduced the number of adherent platelets and the single platelet spreading area on immobilized fibrinogen as well as thrombin-stimulated fibrin clot retraction. Furthermore, pterostilbene substantially prolonged the occlusion time of thrombotic platelet plug formation in mice. This study demonstrated that pterostilbene exhibits a strong activity against platelet activation through the inhibition of integrin α_IIbβ₃-mediated inside-out and outside-in signaling, suggesting that pterostilbene can serve as a therapeutic agent for thromboembolic disorders.     

Parallelizing Complex Streaming Applications on Distributed Scratchpad Memory Multicore Architecture

Multicore processors can provide sufficient computing power and flexibility for complex streaming applications, such as high-definition video processing. For less hardware complexity and power consumption, the distributed scratchpad memory architecture is considered, instead of the cache memory architecture. However, the distributed design poses new challenges to programming. It is difficult to exploit all available capabilities and achieve maximal throughput, due to the combined complexity of inter-processor communication, synchronization, and workload balancing. In this study, we developed an efficient design flow for parallelizing multimedia applications on a distributed scratchpad memory multicore architecture. An application is first partitioned into streaming components and then mapped onto multicore processors. Various hardware-dependent factors and application-specific characteristics are involved in generating efficient task partitions and allocating resources appropriately. To test and verify the proposed design flow, three popular multimedia applications were implemented: a full-HD motion JPEG decoder, an object detector, and a full-HD H.264/AVC decoder. For demonstration purposes, SONY PlayStation \(^{\circledR }\) 3 was selected as the target platform. Simulation results show that, on PS3, the full-HD motion JPEG decoder with the proposed design flow can decode about 108.9 frames per second (fps) in the 1080p format. The object detection application can perform real-time object detection at 2.84 fps at \(1280 \times 960\) resolution, 11.75 fps at \(640 \times 480\) resolution, and 62.52 fps at \(320 \times 240\) resolution. The full-HD H.264/AVC decoder applications can achieve nearly 50 fps.