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1.
Intel's XeonPhi is a highly parallel x86 architecture chip made by Intel. It has a number of novel features which make it a particularly challenging target for the compiler writer. This paper describes the techniques used to port the Glasgow Vector Pascal Compiler to this architecture and assess its performance by comparisons of the XeonPhi with 3 other machines running the same algorithms. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
2.
Performance‐based seismic design, as an alternative to conventional methods of approach, has served engineers and the public rather well during the last two decades. Neither approach guaranties catastrophic collapse prevention nor post‐earthquake realignment and repairs (PERR) due to major seismic events. As a result, most code‐compliant buildings can be regarded as relatively safe but practically disposable. The paper presents a new philosophy that leads to sustainable design of new structures and the upgrading of existing earthquake resisting moment frames. Repairability‐based design (RBD) relies on softening and control rather than strength and resistance to elevate seismic performance to economically viable, physical collapse prevention, damage control, and post‐earthquake realignment and repairs. The new approach was inspired by design led analysis (DLA), performance control (PC), and recent developments in rocking core‐moment frame design. DLA is a displacement based method of analysis with built‐in results. PC is the ability to design a structure in such a way as to expect predetermined modes of response at certain stages of loading, extents of damage, and drift ratios. This paper advocates higher performance objectives than current codes of practice do. Several demonstrative examples have been provided.  相似文献   
3.
One of the most important challenges in treating cancer is the invasion and the angiogenesis of cancer cells. The synthesis of green nanoparticles (NPs) and their use in therapeutic fields is one of the most effective methods with minimal side effects in cancer treatment. In this study, cytotoxic and anti‐angiogenic effects of silver NPs (AgNPs) coated with palm pollen extract [Ag–PP(NPs)] were evaluated. For this purpose, the cells were treated with NPs and then were subjected to trypan blue testing (48 h). Then, the cancer invasion was evaluated by the scratch procedure and the expressions of the vascular endothelial growth factor (VEGF) and its receptor (VEGF‐R) genes were estimated using real‐time PCR assay. Also, the angiogenesis effect of the NPs was investigated with chick chorioallantoic membrane (CAM) assay. The Ag–PP(NPs) induced cytotoxicity on MCF7 cells. The findings also showed that Ag–PP(NPs) inhibit invasive cancer cells and reduce the expression of VEGF and VEGF‐R and significantly reduced the number and vessels lengths and the lengths and weights of the embryos in CAM assay. Ag–PP(NPs) with the induction of cytotoxic effects, metastatic inhibition and anti‐angiogenesis properties should be considered as an appropriate option for treatment of cancerInspec keywords: nanomedicine, genetics, cellular biophysics, toxicology, patient treatment, silver, cancer, biochemistry, biomedical materials, nanoparticles, nanofabrication, membranesOther keywords: minimal side effects, cancer treatment, silver NPs, cancer invasion, vascular endothelial growth factor, receptor genes, VEGF‐R, real‐time polymerase chain reaction assay, angiogenesis effect, chick chorioallantoic membrane assay, MCF7 cells, invasive cancer cells, cytotoxic effects, putative mechanism, anticancer properties, antiangiogenic effects, antiangiogenesis properties, Ag–PP‐induced cytotoxicity, metastatic inhibition, palm pollen extraction, trypan blue testing, time 48.0 hour, Ag  相似文献   
4.
Current discoveries of different forms of carbon nanostructures have motivated research on their applications in various fields. They hold promise for applications in medicine, gene, and drug delivery areas. Many different production methods for carbon nanotubes (CNTs) have been introduced; functionalization, filling, doping, and chemical modification have been achieved, and characterization, separation, and manipulation of individual CNTs are now possible. Parameters such as structure, surface area, surface charge, size distribution, surface chemistry, and agglomeration state as well as purity of the samples have considerable impact on the reactivity of carbon nanotubes. Otherwise, the strength and flexibility of carbon nanotubes make them of potential use in controlling other nanoscale structures, which suggests they will have a significant role in nanotechnology engineering.  相似文献   
5.
In this paper, we present a combination of particle swarm optimization (PSO) and genetic operators for a multi-objective job shop scheduling problem that minimizes the mean weighted completion time and the sum of the weighted tardiness/earliness costs, simultaneously. At first, we propose a new integer linear programming for the given problem. Then, we redefine and modify PSO by introducing genetic operators, such as crossover and mutation operators, to update particles and improve particles by variable neighborhood search. Furthermore, we consider sequence-dependent setup times. We then design a Pareto archive PSO, where the global best position selection is combined with the crowding measure-based archive updating method. To prove the efficiency of our proposed PSO, a number of test problems are solved. Its reliability based on some comparison metrics is compared with a prominent multi-objective genetic algorithm (MOGA), namely non-dominated sorting genetic algorithm II (NSGA-II). The computational results show that the proposed PSO outperforms the above MOGA, especially for large-sized problems.  相似文献   
6.
The TiO2 hollow spheres were synthesized using a green, cheap, and easy process, in which carbonaceous spheres were chosen as the removable template. The prepared materials were characterized by X-ray diffraction (XRD), Field emission scanning electron microscopy (FESEM), Energy-dispersive X-ray spectroscopy (EDX), Atomic force microscopy (AFM), Fourier Transform Infrared Spectroscopy (FTIR), and Brunauer–Emmett–Teller (BET) analysis. According to the results, the obtained mesoporous TiO2 hollow spheres demonstrated an external diameters less than 200?nm with shell thickness around 40?nm. The antibacterial activities of the TiO2 hollow spheres were evaluated against gram-positive (Bacillus subtilis and Staphylococcus aureus) and gram-negative (Escherichia coli and Pseudomonas aeruginosa). No antibacterial activity was found for TiO2 hollow spheres in the used concentrations. TiO2 hollow spheres were loaded with gentamycin as a selected antibiotic to magnify their benefits in biomedical applications. TiO2 hollow spheres exhibited good antibiotic carrier activity for the direct delivery of gentamicin, which was attributed to interaction between gentamicin and surface due to their larger specific surface area, more abundant porous structure, and their spherical morphology. The application of TiO2 hollow spheres as gentamicin carrier undoubtedly opens an avenue to use hollow sphere materials in other drug delivery applications.  相似文献   
7.
ZnAl2O4 and ZnO nanostructure particles and in situ crystallization of zinc aluminate and zinc oxide coating layers on sintered α-Al2O3 and γ-Al2O3 granules by the microwave-assisted combustion method were investigated. For powders, the effects of solution pH value and for coated samples the influence of support type on the structure, microstructure, and photocatalytic activity of powders were studied. Results showed that variation of synthesis pH value caused to considerable change in agglomeration, specific surface area, obtaining up to 88 and 92% yields for zinc aluminate and zinc oxide nanoparticles, respectively. γ-alumina granules were more appropriate supports than the α-alumina ones because of the better photocatalytic activities and lower extent of the attritions for both zinc aluminate and zinc oxide coating layers.  相似文献   
8.
Polystyrene/clay (PS/clay) nanocomposites were synthesized by insitu emulsion and bulk polymerization methods. Sodium montmorillonite (Na-MMT) and two organically modified clays (Cloisite 30B and Cloisite 15A) were employed. The effect of clay swelling method and sonication on the d-spacing of silicate layers was also investigated. The surface morphology of pure PS and PS/clay nanocomposites were comparatively investigated using scanning electron microscopy (SEM). Thermogravimetric analysis (TGA) of PS and PS/clay nanocomposites revealed the improved thermal stability of PS/clay nanocomposites compared to pure PS. Results of optical transparency tests showed the better transparency of nanocomposite films compared to the pure PS film.  相似文献   
9.
Polyethersulfone (PES) is one of the most common polymers used to manufacture membranes. This work focuses on introducing and developing a novel polymer-based membrane applicable in the bio-artificial pancreas. The novel membrane based on the mixture of PES and Pyrolytic carbon (PyC) was studied and compared to PES as a reference. The PES/PyC blend membranes were characterized by top surface SEM, cross section SEM, AFM, contact angle pure water flux, insulin rejection, rejection of immune cells and molecules, and insulin diffusivity performance. In addition, the porosity of the membranes, mean pore size and mean pore density were also measured. The AFM and SEM images indicate that addition of synthesized PyC in the casting solution results in a membrane with high surface and sub-layer porosity and the addition 0.1 wt.% PyC to the casting solution reduced the surface roughness from 22.4 nm to 4.8 nm. The contact angle measurements reveal that the hydrophobicity of pure PES membrane enhanced with increasing the PyC concentration in the casting solution. With the increase of PyC from 0.0 wt.% to 0.1 wt.% in the casting solution, pure water flux reduces from 184 to 153 (L/m2h), insulin rejection reduces from 12 to 9.3%, rejection of immune cells and molecules reduce from 91.8 to 83% and insulin diffusivity increased from1.22E-8 to 1.46E-8. Furthermore, the resulting numbers for the mean pore size, mean pore density, and porosity of the PES-PyC(0.1 wt.%) membrane indicate a considerable improvement compared to pure PES membrane with increasing from 5.5 nm to 7 nm, 26 to 43 pores/area (area stand for the size of membrane surface in which pores were counted), and 68.3% to 84.6%, respectively. At the end, the statistical analysis was performed.  相似文献   
10.
2-Iminothiazolidin-4-one derivatives were synthesized regioselectively in good to high yields by condensation of N,N-disubstituted thioureas and ethyl chloroacetate in the presence of basic ionic liquid [bmim]OH as a catalyst under conventional and ultrasonic irradiation conditions. Under ultrasonic irradiation, the reaction furnished the desired 2-iminothiazolidinones in higher yields (76–87%) and lower reaction times (30–55 min).  相似文献   
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