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Wireless Personal Communications - Biometric authentications systems are being recognized as the better way of securing data or personal devices as they are unique. Face is considered the best way... 相似文献
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Dr. Yuteng Wu Dr. M. Teresa Bertran James Rowley Dr. Ewen D. D. Calder Dhira Joshi Dr. Louise J. Walport 《ChemMedChem》2021,16(20):3185-3188
The major obstacle in applying peptides to intracellular targets is their low inherent cell permeability. Standard approaches to attach a fluorophore (e. g. FITC, TAMRA) can change the physicochemical properties of the parent peptide and influence their ability to penetrate and localize in cells. We report a label-free strategy for evaluating the cell permeability of cyclic peptide leads. Fluorescent tryptophan analogues 4-cyanotryptophan (4CNW) and β-(1-azulenyl)-L-alanine (AzAla) were incorporated into in vitro translated macrocyclic peptides by initiator reprogramming. We then demonstrate these efficient blue fluorescent emitters are good tools for monitoring peptide penetration into cells. 相似文献
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Bharat Joshi Huai-Ren Shih Brian Rose 《Journal of Failure Analysis and Prevention》2018,18(3):486-495
Diffuser plates in exhaust system manifolds are designed to provide uniform flow pattern within the manifold for maximum utilization of the catalytic converter substrate during high-temperature applications. In this paper, failure analysis of a diffuser which survived only 20% duration of a manifold crack test and various design optimization studies of the diffuser plate using computer-aided engineering (CAE) analyses are presented. During the manifold crack test, the failure occurred at the inner and outer periphery of the diffuser. Metallurgical failure analysis coupled with CAE thermal fatigue analysis of the component concluded that thermal fatigue was the root cause of the failure. The new recommended robust design showed considerable improvement in the thermal durability of the diffuser plate assembly. 相似文献
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Kodgirwar Vidya P. Deosarkar Shankar B. Joshi Kalyani R. 《Wireless Personal Communications》2020,110(1):423-444
Wireless Personal Communications - Applications of wireless sensor networks (WSNs) are increasing tremendously to facilitate and establish a link between the physical world and information system.... 相似文献
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Schuessler Benjamin J. Field David P. Overman Nicole R. Joshi Vineet V. 《Metallurgical and Materials Transactions A》2021,52(9):3871-3879
Metallurgical and Materials Transactions A - Uranium alloyed with 10 wt pct Mo (U-10Mo) undergoes discontinuous precipitation (DP) when subjected to sub-eutectoid heat treatment. It is hypothesized... 相似文献
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In this article, we have studied the effect of carbonaceous nanofillers viz. fullerenol (0D), carboxylated multi-wall carbon nanotube (MWCNT, 1D), hydroxylated graphene (2D) and combination of carboxylated CNT and hydroxylated graphene as 3D in thermoplastic polyurethane on the tensile properties of the fabricated cellular structures. The concentration of nano-fillers was varied as 0.1, 1, and 5 wt%. Tensile properties of the nanocomposite cellular structures were measured as per ASTM D882 at 20°C (below glass transition temperature, Tg) and 40°C (above Tg). The results have shown that the tensile strength was found to increase by 200%–300% and the tensile modulus was found to increase by 150%–300% for 2D and 3D nano-fillers while significantly poor results were observed for 0D. However, the test data tensile strength and modulus showed marginal increase at 20°C and marginally low at 40°C for 1D filler. The interfacial adhesion was calculated by using experimental tensile data and the predictive models. The interfacial adhesion parameter (Bσ) calculated using Pukanszky equation was found significantly higher value for 2D (Bσ20 = 195.8) and 3D (Bσ20 = 192.0) fillers while poor adhesion was observed for 0D (Bσ20 = −81.6) fillers. The developed cellular structured materials were also evaluated by attenuated total reflection Fourier transform IR spectra, differential scanning calorimetry, X-ray diffraction, scanning electron microscope, and transmission electron microscope. 相似文献
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