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1.
Metallurgical and Materials Transactions B - Phase equilibria of the ternary CaO-ZnO-SiO2 system have been investigated at 1170 °C to 1691 °C for oxide liquid in equilibrium...  相似文献   
2.
Cell therapy of the post-infarcted myocardium is still far from clinical use. Poor survival of transplanted cells, insufficient regeneration, and replacement of the damaged tissue limit the potential of currently available cell-based techniques. In this study, we generated a multilayered construct from adipose-derived mesenchymal stromal cells (MSCs) modified to secrete stem cell factor, SCF. In a rat model of myocardium infarction, we show that transplantation of SCF producing cell sheet induced activation of the epicardium and promoted the accumulation of c-kit positive cells in ischemic muscle. Morphometry showed the reduction of infarct size (16%) and a left ventricle expansion index (0.12) in the treatment group compared to controls (24–28%; 0.17–0.32). The ratio of viable myocardium was more than 1.5-fold higher, reaching 49% compared to the control (28%) or unmodified cell sheet group (30%). Finally, by day 30 after myocardium infarction, SCF-producing cell sheet transplantation increased left ventricle ejection fraction from 37% in the control sham-operated group to 53%. Our results suggest that, combining the genetic modification of MSCs and their assembly into a multilayered construct, we can provide prolonged pleiotropic effects to the damaged heart, induce endogenous regenerative processes, and improve cardiac function.  相似文献   
3.
Protection of Metals and Physical Chemistry of Surfaces - Based on the concept of collective vibrations of ions in the bulk of metal systems, the frequency of vibrations of an oxygen molecule on...  相似文献   
4.
Protection of Metals and Physical Chemistry of Surfaces - A microporous carbon adsorbent labeled as LCN was prepared by thermochemical synthesis from lignocellulose, and methane adsorption on it...  相似文献   
5.
Phase equilibria of the binary PbO-ZnO and ternary PbO-ZnO-SiO2 systems have been experimentally investigated at 1033–1898?K (760–1625?°C) for oxide liquid in equilibrium with air and solid oxide phases: tridymite or cristobalite (SiO2), willemite (Zn2SiO4), zincite (ZnO), larsenite (PbZnSiO4) and lead-zinc melilite (Pb2ZnSi2O7) covering the ranges of concentrations not studied before. High-temperature equilibration on primary phase or inert metal (platinum) substrates, followed by quenching and direct measurement of the Pb, Zn and Si concentrations in the phases with the electron probe X-ray microanalysis (EPMA) has been used. Liquidus phase equilibrium data is essential for the development of the thermodynamic model.  相似文献   
6.
Metal Science and Heat Treatment - Precision nickel alloy 40KhNYu-VI used for fabricating nonmagnetic precision bearings is studied after nitriding in glow discharge in an experimental facility at...  相似文献   
7.
Glass Physics and Chemistry - Using computer methods (the ToposPro software package), a combinatorial topological analysis and modeling of the self-assembly of the Sc96Mg8Zn600-cP704 (sp. gr. Pa-3...  相似文献   
8.
Powder Metallurgy and Metal Ceramics - The mixing enthalpies of liquid binary Ce–In alloys (0 < x In < 1) at 1500 K are determined by isoperibol calorimetry. The thermodynamic...  相似文献   
9.
The results of studying the structural parameters and strength characteristics of a bioactive membrane are presented. The membrane was obtained based on high-silica glass via modification with silicon polyoxomolybdate. The membrane strength characteristics were simulated under conditions of the maximum pressure of a vacuum water-jet pump of 300 kPa.  相似文献   
10.
The combinatoric and topological analysis and modeling of the self-assembly of the Na26Cd141–hP168 crystal structure (space group Pbcm; a = 5.483 Å, b = 24.519 Å, and c = 14.573 Å; and V = 1895 Å3) are performed using computational methods (the ToposPro software package). Ninety-eight versions of the cluster representation of the 3D atomic network with the number of structural units ranging from four to seven are found. It is determined that polyhedral clusters–precursors C8 = 0@Na2Cd6 and C9 = 0@Na3Cd6 are templates, on the surface of which atomic shells consisting of 38 and 41 atoms are formed. The composition of the two-layer clusters is C46 = 0@(Na2Cd6)@(Na12Cd26) and C50 = 0@(Na3Cd6)@(Na6Cd35). The centers of clusters C46 and C50 are occupied by positions 1a with the symmetry 6/mmm and 2c with the symmetry −6m2. The symmetry and topology codes of the processes of self-assembly of 3D structures from nanoclusters–precursors C46 and C50 are reconstructed.  相似文献   
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