Adaptive epidemic dissemination as a finite-horizon optimal stopping problem

Wireless Networks - Wireless ad hoc networks are characterized by their limited capabilities and their routine deployment in unfavorable environments. This creates the strong requirement to...     

Development of an Easy Multiresidue Method for Fat-Soluble Pesticides in Animal Products Using Gas Chromatography–Tandem Mass Spectrometry

The determination of pesticide residues in animal samples requires several analytical steps which may be time-consuming extraction procedures and with a small scope. For fat-soluble pesticides, the determination of fat is essential as they tend to bioaccumulate in fat. As to address these concerns, an easy acetonitrile-based multiresidue method combined with GC-MS-MS technology for the determination of the fat-soluble analytes was developed and validated on animal products. Analytes from several chemical classes such as diphenyl ethers, pyrethroids, organochlorides, triazoles, carbamide, chlorophenyls, dinitroaniline, organophosphorus, chloroacetamides, benzamides, aromatic hydrocarbon and dicarboximide known, due to their fat-soluble property, to bioaccumulate in animal tissues were selected. The method showed acceptable linearity (r?≥?0.99) and accuracy with recoveries between 70 and 120 % and precision with SD_R?≤?20 % for the majority of the analytes studied. For the analytes that presented accuracy and precision values outside the acceptable limits, the method still is able to serve as a semi-quantitative method. The contribution of the determination of the fat in the results was also investigated. The limit of detection was set at 0.003 mg/kg. The proposed methodology was applied to meat and offal samples from the regional market in Attiki (Greece).     

Wireless Channel State-Aware and Adaptive Epidemic Dissemination in Ad Hoc Networks

Ad hoc networks are characterized by limited resources (e.g. energy, bandwidth). Efficient information dissemination while avoiding excessive energy cost can be achieved through the suitable design of a network. To this end we propose an information dissemination scheme which couples epidemic dissemination with adaptive modulation and coding (AMC). The proposed scheme tunes the message forwarding probability and the coding and modulation mode in order to achieve a balance between maximum coverage over the network and minimum energy expenditure. We achieve this based on the evaluation of suitably defined indicators related to the lower network layers and exploiting information on the current status of the wireless medium. Building on established previous AMC-related work, our simulation results indicate that our scheme brings significant improvement over non-adaptive approaches, comparable with other adaptive epidemic dissemination schemes. Our findings are quite promising for adaptive epidemic-based information dissemination schemes with a strong cross-layer component.     

Exposure to environmental and mainstream tobacco smoke and risk of spontaneous abortion

The present nationwide, multicenter clinical study was carried out in 26 departments of surgery to define the incidence and attendant mortality of intestinal infarction following abdominal aortic surgery, and to identify patients at risk of it. The data consist of 1752 patients who underwent abdominal aortic reconstruction during 1991-1993 as recorded in the Finnish national vascular registry (FINNVASC). Among the 1752 operations, 27 patients treated at 14 different hospitals had intestinal ischemia, and the complete patient records of all 27 cases were reanalyzed. The incidence of bowel infarction was 1.2%. Among patients operated on for a ruptured aneurysm it was 3.1%, whereas 1.0% of patients with nonruptured aneurysm and 0.6% of those operated on for aortoiliac occlusive disease developed intestinal infarction. In 14 patients (67%) the lesion affected the left colon. The overall 30-day mortality rate was 13% but reached 67% among those with intestinal infarction. We conclude that acute intestinal ischemia with bowel infarction is an infrequent but serious complication of abdominal aortic surgery. It is mainly related to surgery due to aneurysmal disease, and patients with occlusive aortoiliac disease present ischemic complications in the intestines less often. Hypotensive patients being treated for ruptured aneurysm are at greatest risk of intestinal ischemia.     

Enzymatic characteristics of recombinant medium isozyme of 2'-5' oligoadenylate synthetase

P69 is an isozyme of the medium size class of human 2'-5' oligoadenylate synthetases. In this study, recombinant P69 was expressed and used for enzymological and structural investigations. Bacterially expressed P69 was inactive whereas the same protein expressed in insect cells was highly active. Whether this difference could be due to differential post-translational modifications of the protein was investigated. Mutations of appropriate residues showed that myristoylation of the protein was not necessary for enzyme activity. In contrast, inhibition of glycosylation of P69, by tunicamycin treatment of the insect cells, produced an enzymatically inactive protein. Recombinant P69 produced in insect cells was purified by affinity chromatography. It was a dimeric glycoprotein, very stable and completely dependent on double stranded (ds) RNA for activity. The enzyme catalyzed the non-processive synthesis of 2'-5'-linked oligoadenylate products containing up to 30 residues. 2'-O-Methylated dsRNA was incapable of activating P69 and a 25-base pair dsRNA was as effective as larger dsRNA. This expression system will be useful for large scale production of P69 and its mutants for structural studies.     

User privacy and modern mobile services: are they on the same path?

Perhaps, the most important parameter for any mobile application or service is the way it is delivered and experienced by the end-users, who usually, in due course, decide to keep it on their software portfolio or not. Most would agree that security and privacy have both a crucial role to play toward this goal. In this context, the current paper revolves around a key question: Do modern mobile applications respect the privacy of the end-user? The focus is on the iPhone platform security and especially on user’s data privacy. By the implementation of a DNS poisoning malware and two real attack scenarios on the popular Siri and Tethering services, we demonstrate that the privacy of the end-user is at stake.     

Lateral bearing capacity of rigid piles near clay slopes

Analytical equations were derived to determine the undrained lateral bearing capacity of rigid piles in cohesive soil. Piles in level ground and piles placed at a distance from the crest of a slope were examined, taking account of the effect of the adhesion at the pile–soil interface. The derived analytical solutions were used to develop charts relating the lateral pile capacity to the pile length/diameter ratio, the pile–soil adhesion, the distance of the point of load application from the ground to the pile diameter ratio, the inclination of the slope and the distance of the pile from the crest of the slope to the pile diameter ratio. They were also used to derive a reduction factor which, when multiplied by the lateral bearing capacity for level ground, gives the bearing capacity of the same pile near a slope. In addition, a critical non-dimensional distance between the pile and the crest of the slope, at which the bearing capacity approaches that for a level ground, was determined. The bearing capacity charts obtained for level ground were compared to the classic Broms' charts and to others derived using several different lateral earth pressure distributions along the pile. Comparisons were also made between the results of the proposed method for piles near slopes and those obtained from charts based on upper bound calculations. Finally, the proposed new method was validated through a comparison with the results of a large number of pile load tests, in which a remarkable agreement was observed between the analytical results and the measurements.