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A laser ablation system has been constructed and used to determine the damage threshold of stainless steel, rhodium and single-, poly- and nanocrystalline molybdenum in vacuum, at a number of wavelengths between 220 nm and 1064 nm using 5 ns pulses. All materials show an increase of the damage threshold with decreasing wavelength below 400 nm. Tests in a nitrogen atmosphere showed a decrease of the damage threshold by a factor of 2–3. Cleaning tests have been performed in vacuum on stainless steel samples after applying mixed Al/W/C/D coatings using magnetron sputtering. In situ XPS analysis during the cleaning process as well ex situ reflectivity measurements demonstrate near complete removal of the coating and a substantial recovery of the reflectivity. The first results also show that the reflectivity obtained through cleaning at 532 nm may be further increased by additional exposure to UV light, in this case 230 nm, an effect which is attributed to the removal of tungsten dust from the surface.  相似文献   
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Abstract

Objective: Orally disintegrating tablets (ODTs) recently have gained much attention to fulfill the needs for pediatric, geriatric, and psychiatric patients with dysphagia. Aim of this study was to develop new ODT formulations containing mirtazapine, an antidepressant drug molecule having bitter taste, by using simple and inexpensive preparation methods such as coacervation, direct compression and to compare their characteristics with those of reference product (Remereon SolTab).

Materials and methods: Coacervation method was chosen for taste masking of mirtazapine. In vitro characterization studies such as diameter and thickness, weight variation, tablet hardness, tablet friability and disintegration time were performed on tablet formulations. Wetting time and in vitro dissolution tests of developed ODTs also studied using 900?mL 0.1?N HCl medium, 900?mL pH 6.8 phosphate buffer or 900?mL pH 4.5 acetate buffer at 37?±?0.2?°C as dissolution medium.

Results: Ratio of Eudragit® E-100 was chosen as 6% (w/w) since the dissolution profile of A1 (6% Eudragit® E-100) was found closer to the reference product than A2 (4% Eudragit® E-100) and A3 (8% Eudragit® E-100). Group D, E and F formulations were presented better results in terms of disintegration time. Dissolution results indicated that Group E and F formulations showed optimum properties in all three dissolution media.

Discussion: Formulations D1, D4, D5, E3, E4, F1 and F5 found suitable as ODT formulations due to their favorable disintegration times and dissolution profiles.

Conclusion: Developed mirtazapine ODTs were found promising in terms of showing the similar characteristics to the original formulation.  相似文献   
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The rapid growth in the mobile application market presents a significant challenge to find interesting and relevant applications for users. An experimental study was conducted through the use of a specifically designed mobile application, on users’ mobile phones. The goals were; first, to learn about the users’ personality and the applications they downloaded to their mobile phones, second to recommend applications to users via notifications through the use of experimental mobile application and learn about user behavior in mobile environment. The question of how the personality features of users affect their compliance to recommendations is explored in this study. It is found that conscientiousness is positively related with accepting recommended applications and being agreeable is related with the preference for the applications of editor’s choice. Furthermore, in this study, applications owned by the user and the composition of applications under categories and their relation with personality features are explored. It is shown that the number of user owned applications and their category differ according to gender and personality. Having similar applications and the number of applications owned under specific categories increase the probability of accepting recommended applications.  相似文献   
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The effect of corrosion on the bond strength between reinforcement bars and concrete was studied in a series of experiments. An accelerated corrosion method was used to corrode the reinforcement bars embedded in concrete specimens. Pullout tests were performed to develop an empirical model for the ultimate bond strength by evaluating bond strengths in two different concrete mixes, three concrete cover depths and different mass losses of reinforcement bars after corrosion. Bond-slip relationships for the different corrosion levels were compared. It was found that the relationship between bond strength and concrete strength in uncorroded specimens differed from that of corroded specimens set in high-strength concrete because of brittleness in the corroded specimens, which caused a sudden loss of bond strength. The results revealed that specimens with higher concrete strength levels and corroded reinforcements showed a higher percentage of bond strength degradation due to concrete cracking during the pullout tests.  相似文献   
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In this study, SiC particles were incorporated by using Friction Stir Processing (FSP), into the commercially pure aluminium to form particulate surface layers. Samples were subjected to the various tool rotating and traverse rates with and without SiC powders. Microstructural observations were carried out by employing optical microscopy of the modified surfaces. Mechanical properties like hardness and plate bending were also evaluated. The results showed that increasing rotating and traverse rate caused a more uniform distribution of SiC particles. The hardness of produced composite surfaces was improved by three times as compared to that of base aluminium. Bending strength of the produced metal matrix composite was significantly higher than processed plain specimen and untreated base metal.  相似文献   
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The consumer decision process is a widely accepted model covering consumer activities, and accordingly contains five interrelated stages: problem recognition, information search, evaluation of alternatives, purchase, and post-purchase evaluation. In order to help consumers deal with challenges associated with all these stages, mobile information systems bring significant capabilities, as in other application domains. However, related prior research is mostly restricted to the individual stages of the process. Since the stages are interrelated, and the data collected in one are also valuable for another, we propose a mobile framework designed to provide assistance in all stages of the Consumer Decision Process, named MobileCDP. A prototype is also implemented and evaluated to show the applicability of the framework. Experiments show that the functions provided by the prototype are useful, well integrated, and easy to use. Moreover, statistical analysis of the results proves that the prototype reduces time, costs, and cognitive effort of the user.  相似文献   
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Produced water, which is co-produced during oil and gas manufacturing, represents one of the largest sources of oily wastewaters. Therefore, treatment of this produced water may improve the economic viability and lead to a new source of water for beneficial use. In this study a submerged hollow fiber membrane bioreactor (MBR) has been studied experimentally for the treatment of brackish oil and natural gas field produced water. This type of wastewater is also characterized with relatively moderate to high amount of salt, oil and total petroleum hydrocarbons (TPH). However, the bacteria which are growing in conventional activated sludge and MBR cannot survive at these strict conditions, therefore acclimation of the bacteria is of vital importance. The performance of the biological system, membrane permeability, the rate and extent of TPH biodegradability have been investigated under different sludge age and F/M ratios. The results obtained by gas chromatography analyses showed that the MBR system could be very effective in the removal of TPH from produced water and a significant improvement in the effluent quality was achieved.  相似文献   
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