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排序方式: 共有753条查询结果,搜索用时 19 毫秒
1.
Engineering with Computers - In this paper, we will focus on adaptive meshing and re-meshing. We present an original approach, based on Quadtree and Octree, to construct the initial mesh and refine... 相似文献
2.
Fire hazard in nuclear power plants (NPPs) is particularly often investigated as potential cause of safety equipment failure and confinement loss. Many fire events recorded in NPPs involve electric cables, widely used throughout facilities. IRSN is developing the CALIF3S/ISIS computational fluid dynamics software devoted to fire simulation in large‐scale confined and mechanically ventilated compartments. This paper presents two aspects of the CALIF3S/ISIS code ability to simulate fires. The first one concerns vertical and horizontal spreading of a cable tray fire in open atmosphere using an approach based on the FLASH‐CAT cable fire spread model. Resorting to the suitable parameters of the FLASH‐CAT model based on video fire analyses of tests enables to properly compute the heat release rate of the fire. The second aspect concerns the ability to simulate the evolution and consequences of fires in confined and mechanically ventilated compartments. For these cases, the heat release rate measured during the corresponding experiment is used as input data for the calculations. The predicted evolutions of pressure or gas temperatures are in relatively good accordance with the experiments. The major discrepancy concerns gas concentrations in the fire room which is attributed to a lack of information about the properties of the fuel material. 相似文献
3.
In high-speed rolling element bearings, the drag forces can be prominent and it is demonstrated in this investigation that the classical models may not be appropriate for correctly estimating this power loss contribution. A modification of the models is thus proposed, including the usual drag forces formulation relying upon the drag coefficient to be evaluated from a numerical computational fluid dynamics (CFD) approach. A three-dimensional approach that considers both the rings and the cylinder ends seems the only adequate approach to be used because a two-dimensional approach predicts a drag coefficient value that is too low. When using the former computed drag coefficient for the evaluation of the total power losses, high values of oil volume fraction must be employed to recover the measured power losses. 相似文献
4.
Papadopoulos Georgios Z. Mavromatis Alex Gallais Antoine Theoleyre Fabrice 《Wireless Networks》2021,27(1):367-381
Wireless Networks - Internet of things consist in the deployment of constrained and battery-powered devices with a radio interface. Most industrial applications require to respect strict... 相似文献
5.
Dr. Ivan A. Yaremenko Dr. Paolo Coghi Parichat Prommana Congling Qiu Peter S. Radulov Yuanqing Qu Yulia Yu. Belyakova Dr. Enrico Zanforlin Dr. Vladimir A. Kokorekin Yuki Yu Jun Wu Prof. Fabrice Fleury Dr. Chairat Uthaipibull Dr. Vincent Kam Wai Wong Prof. Alexander O. Terent'ev 《ChemMedChem》2020,15(13):1118-1127
This article discloses a new horizon for the application of peroxides in medical chemistry. Stable cyclic peroxides are demonstrated to have cytotoxic activity against cancer cells; in addition a mechanism of cytotoxic action is proposed. Synthetic bridged 1,2,4,5-tetraoxanes and ozonides were effective against HepG2 cancer cells and some ozonides selectively targeted liver cancer cells (the selectivity indexes for compounds 11 b and 12 a are 8 and 5, respectively). In some cases, tetraoxanes and ozonides were more selective than paclitaxel, artemisinin, and artesunic acid. Annexin V flow-cytometry analysis revealed that the active ozonides 22 a and 23 a induced cell death of HepG2 by apoptosis. Further study showed that compounds 22 a and 23 a exhibited a strong inhibitory effect on P-glycoprotein (P-gp/ABCB5)-overexpressing HepG2 cancer cells. ABCB5 is a key player in the multidrug-resistant phenotype of liver cancer. Peroxides failed to demonstrate a direct correlation between oxidative potential and their biological activity. To our knowledge this is the first time that peroxide diastereoisomers have been found to show stereospecific antimalarial action against the chloroquine-sensitive 3D7 strain of Plasmodium falciparum. Stereoisomeric ozonide 12 b is 11 times more active than stereoisomeric ozonide 12 a (IC50=5.81 vs 65.18 μm ). Current findings mean that ozonides merit further investigation as potential therapeutic agents for drug-resistant hepatocellular carcinoma. 相似文献
6.
Julien Moriceau Patrick Houizot Theany To Abdessamad Mougari Hervé Orain Fabrice Celarié Tanguy Rouxel 《Journal of the European Ceramic Society》2021,41(1):838-848
The effect of spherulitic crystallization on the elastic moduli and fracture toughness of a barium aluminum silicate glass was investigated. The crystallization process results in Ba2Si3O8 phase and is initiated from Ba rich nuclei. Nucleation is optimal in the 690-720 °C interval. Young’s modulus is increased by 12.5% when the glass-ceramic conversion is nearly complete. Nevertheless, as the size and the volume fraction of crystals are increased, some microcracking shows up upon cooling from the crystallization temperature. An optimal improvement of the fracture toughness (SEPB method) by 27 % is observed for a 49 % volume fraction of 5 to 10 μm large spherulites. 相似文献
7.
8.
Vincent Cantarel David Lambertin Arnaud Poulesquen Fabrice Leroux Guillaume Renaudin Fabien Frizon 《Ceramics International》2018,44(9):10558-10568
This work investigates emulsion templating to synthesize hexadecane oil/geopolymer composites. In a system with hexadecane as the internal (dispersed) phase and an alkali activated continuous phase without added surfactant, adding aluminosilicate clay particles does not increase resistance against creaming or coalescence, while adding a surfactant (L35 or CTAB) stabilizes the solid-liquid interface. Infrared studies and rheological studies of the associated geopolymerization determined that the presence of the organic phase or surfactant has no significant effect on the geopolymerization kinetics, as determined by the change in time of the Si-O-T IR stretching frequency and the rheological moduli involved during the process. The stabilization of the organic template is reminiscent of Pickering emulsion even though we employ a much greater amount of inorganic material for geopolymer formation. Although the addition of surfactant has a significant effect on the behavior of the paste, the percolation of the network remains unmodified, highlighting the fact that the phenomenon is not dependent on viscosity. Finally, rheological measurements were used to obtain the mass fractal dimension of the as-made gel network, which is able to differentiate the interfacial effect between surfactant molecules with a slightly denser interphase when a cationic surfactant is used. 相似文献
9.
Pauline Glatz Monique Comte Lionel Montagne Bertrand Doumert Fabrice Cousin Laurent Cormier 《Journal of the American Ceramic Society》2020,103(9):4969-4982
Li2O-Al2O3-SiO2 (LAS) glass-ceramics have important industrial applications and bulk nucleation is usually achieved by using nucleating agents. In particular, P2O5 is an efficient agent in glasses containing a low level of Al2O3 but its role in the first stages of nucleation is not well established. In this study, we combine structural investigations from local to mesoscales to describe the structural evolution during crystallization of LAS glass-ceramics. Local environment is probed using 29Si and 31P MAS-NMR, indicating organization of P in poorly crystallized Li3PO4 species prior to any crystallization. To better understand the detailed nanoscale changes of the glass structure, 31P-31P DQ-DRENAR homonuclear correlation experiments have been carried out, revealing the gradual segregation of P atoms associated with the formation of disordered Li3PO4. Small-angle neutron scattering data also show the apparition of nanoscale heterogeneities associated with Li3PO4 species upon heating treatments and allow the determination of their average sizes. These new structural information enhance our understanding of the role of P in nucleation mechanisms. Nucleation is initiated by gradual change in P environment implying P segregation upon heating treatments, forming disordered Li3PO4 heterogeneities. The segregation of P atoms enables the precipitation of meta- and disilicate phases. 相似文献
10.
David Fernández-Gutierrez Marc Veillette Antonio Avalos Ramirez Anne Giroir-Fendler Nathalie Faucheux Michèle Heitz 《加拿大化工杂志》2020,98(1):54-61
The present study aimed to evaluate the potential use of whey to produce 2,3-BD via the fermentation of lactose and its monosaccharides, glucose and galactose, in a synthetic culture medium (medium 9, M9) using a modified strain of Escherichia coli K12 MG1655 (E. coli JFR12) at a 0.1 L/L (10 vol%) inoculum ratio, 37 °C, atmospheric pressure, an initial pH 7.4, and 100 rpm for 72 h varying the saccharide concentration from 12.5, 25, and 50 g/L. The 2,3-BD yield was ∼80 % of the theoretical yield using 25 g/L of glucose and lactose, corresponding to 0.38 g/g saccharides at a fermentation time of 48 h (glucose) and 72 h (lactose). However, the 2,3-BD yield was halved (0.19 g/g galactose), fermenting 25 g/L of galactose at 48 h. Taking into account these results, two important conclusions were determined: i) E. coli JFR12 could transform galactose into 2,3-BD although its yield was half of the yield observed with glucose at 48 h; and ii) E. coli JFR12 was as efficient as other natural 2,3-BD producers such as Klebsiella species fermenting lactose. However, the E. coli strain has the advantage of being an innocuous strain. To the best of our knowledge, there is no other study presenting the production of 2,3-BD from galactose and lactose with a genetically modified E. coli strain. 相似文献