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排序方式: 共有1366条查询结果,搜索用时 15 毫秒
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Pavel Strunz Debashis Mukherji Přemysl Beran Ralph Gilles Lukas Karge Michael Hofmann Markus Hoelzel Joachim Rösler Gergely Farkas 《Metals and Materials International》2018,24(5):934-944
An addition of boron largely increases the ductility in polycrystalline high-temperature Co–Re alloys. Therefore, the effect of boron on the alloy structural characteristics is of high importance for the stability of the matrix at operational temperatures. Volume fractions of ε (hexagonal close-packed—hcp), γ (face-centered cubic—fcc) and σ (Cr2Re3 type) phases were measured at ambient and high temperatures (up to 1500 °C) for a boron-containing Co–17Re–23Cr alloy using neutron diffraction. The matrix phase undergoes an allotropic transformation from ε to γ structure at high temperatures, similar to pure cobalt and to the previously investigated, more complex Co–17Re–23Cr–1.2Ta–2.6C alloy. It was determined in this study that the transformation temperature depends on the boron content (0–1000 wt. ppm). Nevertheless, the transformation temperature did not change monotonically with the increase in the boron content but reached a minimum at approximately 200 ppm of boron. A probable reason is the interplay between the amount of boron in the matrix and the amount of σ phase, which binds hcp-stabilizing elements (Cr and Re). Moreover, borides were identified in alloys with high boron content. 相似文献
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Alawiya Reslan Juliano G. Haddad Liadrine Moukendza Koundi Philippe Desprs Jean-Loup Bascands Gilles Gadea 《International journal of molecular sciences》2021,22(5)
Mosquito-borne Zika virus (ZIKV) became a real threat to human health due to the lack of vaccine and effective antiviral treatment. The virus has recently been responsible for a global outbreak leading to millions of infected cases. ZIKV complications were highlighted in adults with Guillain–Barré syndrome and in newborns with increasing numbers of congenital disorders ranging from mild developmental delays to fatal conditions. The ability of ZIKV to establish a long-term infection in diverse organs including the kidneys has been recently documented but the consequences of such a viral infection are still debated. Our study aimed to determine whether the efficiency of ZIKV growth in kidney cells relates to glucose concentration. Human kidney HK-2 cells were infected with different ZIKV strains in presence of normal and high glucose concentrations. Virological assays showed a decrease in viral replication without modifying entry steps (viral binding, internalization, fusion) under high glucose conditions. This decrease replication was associated with a lower virus progeny and increased cell viability when compared to ZIKV-infected HK-2 cells in normal glucose concentration. In conclusion, we showed for the first time that an elevated glucose level influences ZIKV replication level with an effect on kidney cell survival. 相似文献
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Nancy Soliman Gilles Gasser Christophe M. Thomas 《Advanced materials (Deerfield Beach, Fla.)》2020,32(47):2003294
Ru(II) polypyridyl complexes are compounds of great interest in cancer therapy due to their unique photophysical, photochemical, and biological properties. For effective treatment, they must be able to penetrate tumor cells effectively and selectively. The development of nanoscale carriers capable of delivering Ru(II) polypyridyl complexes has the potential to passively or selectively enhance their cellular uptake in tumor cells. Many different strategies have been explored to incorporate Ru(II) polypyridyl complexes into a variety of nanosized constructs, ranging from organic to inorganic materials. Herein, recent developments in nanomaterials loaded with Ru(II) polypyridyl complexes are highlighted. Their rational design, preparation, and physicochemical properties are described, and their potential applications in cancer therapy are eventually discussed. 相似文献
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Melissa Assad-Bustillos Juliette Palier Hanitra Rabesona Yvan Choiset Guy Della Valle Gilles Feron 《Journal of texture studies》2020,51(1):134-143
This study investigated the digestibility of proteins in a pea protein-fortified sponge cake, as well as the impact of the degree of structure of the bolus produced by elderly subjects on the digestibility of proteins by combining ex vivo and in vitro approaches via the standardized protocol INFOGEST. The sponge cakes were consumed by a group of 20 elderly subjects with contrasting physiology, their boli were recovered just before swallowing, and their apparent viscosity was measured to delineate the bolus degree of structure. According to this criterion, two pools were formed with boli from subjects selected at the extremes: low viscosity and high viscosity, with apparent viscosity values (at 120 s−1) of 124 ± 18 and 208 ± 19 Pa s, respectively. The sponge cakes and the two pools underwent in vitro digestion. Protein hydrolysis kinetics was followed by measuring the released primary amino groups (NH2) and by sodium-dodecyl-sulfate polyacrylamide gel electrophoresis at different time points. For all samples, the representative bands of pea proteins disappear gradually during digestion, accompanied by the appearance of bands indicating the presence of proteins with MW < 15 kDa. In addition, the NH2 concentrations increase over time and do not differ between sponge cake and pea protein isolate. Moreover, the degree of structure of the food bolus has no significant effect on the concentration of NH2 released. These results showed that pea proteins in a fortified sponge cake are bioaccessible under standardized conditions and that the degree of structure of the bolus did not influence protein digestibility for these foods. 相似文献
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Laterally Ordered Sub‐10 nm Features Obtained From Directed Self‐Assembly of Si‐Containing Block Copolymer Thin Films 下载免费PDF全文
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Ali Moussawi Gilles Lubineau Jiangping Xu Bing Pan 《International journal for numerical methods in engineering》2015,102(7):1431-1448
The post‐treatment of (3D) displacement fields for the identification of spatially varying elastic material parameters is a large inverse problem that remains out of reach for massive 3D structures. We explore here the potential of the constitutive compatibility method for tackling such an inverse problem, provided an appropriate domain decomposition technique is introduced. In the method described here, the statically admissible stress field that can be related through the known constitutive symmetry to the kinematic observations is sought through minimization of an objective function, which measures the violation of constitutive compatibility. After this stress reconstruction, the local material parameters are identified with the given kinematic observations using the constitutive equation. Here, we first adapt this method to solve 3D identification problems and then implement it within a domain decomposition framework which allows for reduced computational load when handling larger problems. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献