Study of Corrosion Behavior and In Vitro Bioactivity of Single NbSi2 and Duplex NbSi2/Nb5Si3 Coatings on Nb Substrates for Biomedical Applications

Protection of Metals and Physical Chemistry of Surfaces - Single NbSi2 and duplex NbSi2/Nb5Si3 coatings were successfully applied on Nb substrates using halide activated pack cementation (HAPC)...     

Non-blind Arnold scrambled hybrid image watermarking in YCbCr color space

Microsystem Technologies - Due to fast technological development, human beings generally depend upon computer and other digital equipments in different areas of concern/applications. Therefore,...     

Structurally Diverse Histone Deacetylase Photoreactive Probes: Design,Synthesis, and Photolabeling Studies in Live Cells and Tissue

Histone deacetylase (HDAC) activity is modulated in vivo by post-translational modifications and formation of multiprotein complexes. Novel chemical tools to study how these factors affect engagement of HDAC isoforms by HDAC inhibitors (HDACi) in cells and tissues are needed. In this study, a synthetic strategy to access chemically diverse photoreactive probes (PRPs) was developed and used to prepare seven novel HDAC PRPs 9 – 15 . The class I HDAC isoform engagement by PRPs was determined in biochemical assays and photolabeling experiments in live SET-2, HepG2, HuH7, and HEK293T cell lines and in mouse liver tissue. Unlike the HDAC protein abundance and biochemical activity against recombinant HDACs, the chemotype of the PRPs and the type of cells were key in defining the engagement of HDAC isoforms in live cells. Our findings suggest that engagement of HDAC isoforms by HDACi in vivo may be substantially modulated in a cell- and tissue-type-dependent manner.     

Stability enhancement of induction generator–based series compensated wind power plants by alleviating subsynchronous torsional oscillations using BFOA‐optimal controller tuned STATCOM

In this paper, a STATCOM (static synchronous compensator) is used to encounter the potential SSR (subsynchronous resonance) observed by IG (Induction Generator) based series compensated wind farms. The basic controller used for STATCOM control is identical to that of the literature. An idea of a unique meta‐heuristic swarm‐based optimization technique called BFOA (bacterial foraging optimization algorithm) based optimal‐controller is introduced for optimal parameter selection of the basic controller used in the control scheme of the STATCOM. The investigation is carried out with 500 MW IG‐based wind farm exposed to three‐phase LLL‐G fault close to the PCC (point of common coupling) and implemented with MATLAB in both steady and transient states for the three different cases, namely, without STATCOM, with the basic STATCOM controller, and in the presence of the proposed BFOA‐optimal controller‐based STATCOM. In both the states, the observed eigenvalues of the test system, together with the time domain results of the generator rotor dynamics for three distinct cases, reveals the effectiveness of the suggested BFOA‐optimal controller tuned STATCOM in mitigating the potential SSR.     

Self generating square/triangular wave and pulse width modulator using a single MO-CCCDTA

A self-generating square/triangular wave and pulse width modulator (PWM) using multiple output current controlled current differencing transconductance amplifier (MO-CCCDTA) is presented. To obtain all the three functions simultaneously from the same topology, the MO-CCCDTA is modified a little bit. The characterisation of the modified MO-CCCDTA structure shows that the parasitic resistances at input terminals (n and p) can be varied via bias current. The maximum useful frequency range is found to be 635 MHz, which is higher than the available literature. The waveform generator and PWM circuit use only one MO-CCCDTA, one grounded capacitor and no resistor; hence suitable for IC implementation. The duty cycle of proposed pulse width modulation can be tuned by bias current of MO-CCCDTA over a wide range. The performances of the proposed block and its applications (square/triangular/PWM) are verified by PSPICE simulation using TSMC 0.35 µm technology. The power consumption is about 1.12 mW. To verify experimentally, a prototype of MO-CCCDTA has been made using commercially available ICs (AD844AN and CA3080) on printed circuit board. The simulation and experimental results verify theoretical proposition well. Monte carlo simulation is carried out, which proves satisfactory performance of the proposed circuit against mismatches. The performance of the proposed circuit is also verified through pre-layout and post-layout simulation results. The required chip area is only 22.415 × 14.6 µm².     

Synthesis,optimization and characterization of PVA-co-poly(methacrylic acid) green adsorbents and applications in environmental remediation

Polymer Bulletin - The present paper is focused on the synthesis and optimization of a green PVA-co-poly(MAA) adsorbent by free radical polymerization using N,N′-methylene-bis-acrylamide and...     

Deep transfer modeling for classification of Maize Plant Leaf Disease

Multimedia Tools and Applications - Currently, Deep Learning is playing an influential role for Image analysis and object classification. Maize’s diseases reduce production that subsequently...     

Fabrication and optimization of polypyrrole/cerium oxide/glassy carbon sensing platform for the electrochemical detection of flupirtine

Journal of Applied Electrochemistry - In spite of single nanomaterials, nanocomposites have come to be the superior modifying materials for electrochemical sensing. Herein, the highly...     

Double emulsion‐encapsulated guggul exhibits improved in vivo hypocholesterolaemic action in rats

Guggul tree or Commiphora mukul is a small thorny herb having remarkable hypocholesterolaemic properties. Its therapeutic effects are because of its biocomponent guggulsterones, especially guggulsterone E and Z. In this research, double emulsion‐based spread was tried to improve the bioavailability of the herb guggul in in vivo rat model. The effect of the different diets with encapsulated and nonencapsulated guggul was evaluated and compared after 6 weeks, based on the final body weight and analysis of organs, serum and faeces of normal and hypercholesterolaemic (H) rats. It was evident from the results that double emulsion‐encapsulated guggul showed better control on weight of H rats (25.98% lower), inhibition of HMG CoA reductase (3.95 times less) activity and reduction in atherosclerotic index (47.2%), as compared to diet with unencapsulated guggul. Encapsulation of guggul also improved faecal excretion of bile acids, lipids and total cholesterol in H and normal rats.     

A Unified Decision-Making Technique for Analysing Treatments inPandemicContext

The COVID-19 pandemic has triggered a global humanitarian disaster that has never been seen before. Medical experts, on the other hand, are undecided on the most valuable treatments of therapy because people ill with this infection exhibit a wide range of illness indications at different phases of infection. Further, this project aims to undertake an experimental investigation to determine which treatments for COVID-19 disease is the most effective and preferable. The research analysis is based on vast data gathered from professionals and research journals, making this study a comprehensive reference. To solve this challenging task, the researchers used the HF AHP-TOPSIS Methodology, which is a well-known and highly effective Multi-Criteria Decision Making (MCDM) technique. The technique assesses the many treatment options identified through various research papers and guidelines proposed by various countries, based on the recommendations of medical practitioners and professionals. The review process begins with a ranking of different treatments based on their effectiveness using the HF-AHP approach and then evaluates the results in five different hospitals chosen by the authors as alternatives. We also perform robustness analysis to validate the conclusions of our analysis. As a result, we obtained highly corroborative results that can be used as a reference. The results suggest that convalescent plasma has the greatest rank and priority in terms of effectiveness and demand, implying that convalescent plasma is the most effective treatment for SARS-CoV-2 in our opinion. Peepli also has the lowest priority in the estimation.