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排序方式: 共有10000条查询结果,搜索用时 19 毫秒
1.
Patricia A. Miguez Stephen A. Tuin Adam G. Robinson Joyce Belcher Prapaporn Jongwattanapisan Kimberly Perley Vinicius de Paiva Gon«alves Arash Hanifi Nancy Pleshko Elisabeth R. Barton 《International journal of molecular sciences》2021,22(6)
This study evaluated the direct effect of a phytochemical, hesperidin, on pre-osteoblast cell function as well as osteogenesis and collagen matrix quality, as there is little known about hesperidin’s influence in mineralized tissue formation and regeneration. Hesperidin was added to a culture of MC3T3-E1 cells at various concentrations. Cell proliferation, viability, osteogenic gene expression and deposited collagen matrix analyses were performed. Treatment with hesperidin showed significant upregulation of osteogenic markers, particularly with lower doses. Mature and compact collagen fibrils in hesperidin-treated cultures were observed by picrosirius red staining (PSR), although a thinner matrix layer was present for the higher dose of hesperidin compared to osteogenic media alone. Fourier-transform infrared spectroscopy indicated a better mineral-to-matrix ratio and matrix distribution in cultures exposed to hesperidin and confirmed less collagen deposited with the 100-µM dose of hesperidin. In vivo, hesperidin combined with a suboptimal dose of bone morphogenetic protein 2 (BMP2) (dose unable to promote healing of a rat mandible critical-sized bone defect) in a collagenous scaffold promoted a well-controlled (not ectopic) pattern of bone formation as compared to a large dose of BMP2 (previously defined as optimal in healing the critical-sized defect, although of ectopic nature). PSR staining of newly formed bone demonstrated that hesperidin can promote maturation of bone organic matrix. Our findings show, for the first time, that hesperidin has a modulatory role in mineralized tissue formation via not only osteoblast cell differentiation but also matrix organization and matrix-to-mineral ratio and could be a potential adjunct in regenerative bone therapies. 相似文献
2.
Combustion, Explosion, and Shock Waves - Mathematical models constructed in the macroscopic approximation are used to perform a theoretical study of volume and wave synthesis in a hybrid mixture... 相似文献
3.
Avdeev Ya. G. Kuznetsov D. S. Kuznetsov Yu. I. 《Protection of Metals and Physical Chemistry of Surfaces》2021,57(7):1307-1312
Protection of Metals and Physical Chemistry of Surfaces - Impedance spectroscopy was used to study the adsorption of the IFKhAN-92 inhibitor, a triazole derivative, on cathodically polarized... 相似文献
4.
Kaio C. S. Rodrigues Ivan I. K. Veloso Marcelo P. A. Ribeiro Antonio J. G. Cruz Alberto C. Badino 《加拿大化工杂志》2021,99(1):401-409
Fast, simple, accurate, and inexpensive methods for obtaining analyte concentration data are desirable in the industrial sector. In the present study, the use of Fourier transform mid‐infrared (FT‐MIR) spectroscopy, combined with partial least squares (PLS) regression, was investigated as a tool for real‐time monitoring of processes of ethanol absorption in glycols. Calibration was performed using simple synthetic samples containing ethanol, water, and monoethylene glycol (MEG) or diethylene glycol (DEG). The PLS models presented excellent performance, with correlation coefficients (R2) close to unity and root‐mean‐square errors of cross‐validation (RMSECV) and prediction (RMSEP) lower than 2% of the calibration data ranges for both analytes (ethanol and water) in both absorbents (MEG and DEG). The monitoring technique developed has potential to be applied in absorption processes and could also be used in other large‐scale unit operations, providing information in real time and enhancing process control. 相似文献
5.
Seplyarskii B. S. Kochetkov R. A. Lisina T. G. Abzalov N. I. 《Combustion, Explosion, and Shock Waves》2021,57(3):334-342
Combustion, Explosion, and Shock Waves - This paper touches upon the effect of a polyvinyl butyral content (0–2.3%) on the combustion of a Ti + C granular... 相似文献
6.
以某型静态混合器为研究对象,运用CFD软件ANSYS CFX,借助欧拉–拉格朗日方法,在SST湍流模型下进行气液混合性能分析,得到内部流场的流动与压降规律。研究结果表明:气液两相流流经孔盘通孔,强化流体间的相互作用,对气液的混合具有促进作用;随着雷诺数的增加,气液两相流流经混合器的压降呈明显增大趋势,且混合器中局部压降与元件数成正比,当雷诺数大于2.6×105时,两相流在混合器中压降更加显著。 相似文献
7.
Lucas F. de Lima Cristiane C. Maciel André L. Ferreira Rafael J. G. Rubira Carlos J. L. Constantino Marystela Ferreira 《应用聚合物科学杂志》2021,138(5):49750
In this paper, we report the controlled fabrication of layer-by-layer (LbL) films deposited on gold substrates with three different supramolecular architectures using polypyrrole (Ppy) and magnetite nanoparticles (Fe3O4-np), besides conventional poly(allylamine hydrochloride) (PAH) e poly(vinyl sulfonic acid) (PVS) polyelectrolytes, demonstrating the synergistic effect between Ppy and Fe3O4-np such as a result of their interaction. Modified gold electrodes were analyzed by contact angle (wettability), surface plasmon resonance (SPR), raman spectroscopy, cyclic voltammetry, and electrochemical impedance spectroscopy. The (Fe3O4-np/Ppy)3 architecture was also evaluated by scanning electron microscopy. The modified gold electrodes present more homogeneous covering, higher electron transfer and a decrease of resistance with the incorporation of the nanostructured materials such as Ppy and Fe3O4-np forming (Fe3O4-np/Ppy)3 LbL film. The results carried out in this study suggest that the (Fe3O4-np/Ppy)3 LbL film can be applied as a possible electrochemical or optical non-enzymatic sensor for analytical detection. 相似文献
8.
Lennard F. Torres Zach McCaffrey Wisdom Washington Tina G. Williams Delilah F. Wood William J. Orts Colleen M. McMahan 《应用聚合物科学杂志》2021,138(28):50684
This study explored the feasibility of using torrefied biomass as a reinforcing filler in natural rubber compounds. Carbon black was then replaced with the torrefied biomass in elastomer formulations for concentrations varying from 0% to 100% (60 parts per hundred rubber or phr total). Their influence on the curing process, dynamic properties, and mechanical properties was investigated. Results were compared with the properties of vulcanizates containing solely carbon black fillers. Time to cure (t90) for compounds with torrefied biomass fillers increased, while filler-filler interactions (ΔG') decreased, compared to carbon black controls. At low strains, the tan δ values of the torrefied fillers vulcanizates were similar to the controls. Incorporation of torrefied biomass into natural rubber decreased compound tensile strength and modulus but increased elongation. Replacement with torrefied fillers resulted in a weaker filler network in the matrix. Still, results showed that moderate substitution concentrations (~20 phr) could be feasible for some natural rubber applications. 相似文献
9.
10.
Michelle Greenough Zeyu Zhao Luiz G. Jacobsohn Jianhua Tong Rajendra K. Bordia 《Journal of the European Ceramic Society》2021,41(12):5882-5889
This study focuses on the chemistry, thermal stability, and electrical conductivity of low/intermediate pyrolysis temperature (700?900 °C) polysiloxane derived ceramics. These ceramics were modified with additional carbon derived from divinylbenzene (DVB) added to the precursor. Their electrical properties were investigated for potential uses in micro-electrical mechanical systems (MEMS) and anodes for lithium batteries. The microstructure and chemical composition was investigated by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), Raman spectroscopy, and x-ray photoelectron spectroscopy (XPS); thermogravimetric analysis (TGA) provided insight into the thermal stability; and electrochemical impedance spectroscopy (EIS) into the electrical properties of the material. The increase of pyrolysis temperature and carbon content lead to an enhancement of the electrical conductivity, higher than previously reported values for intermediate pyrolysis temperature SiOC polymer derived ceramics. A limit of the amount of DVB that can be added to PHMS to produce a hybrid precursor has also been obtained. 相似文献