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1.
In this article, we described a simple and rapid method for fabrication of droplet microfluidic devices on polystyrene substrate
using a CO2 laser system. The effects of the laser power and the cutting speed on the depth, width and aspect ratio of the microchannels
fabricated on polystyrene were investigated. The polystyrene microfluidic channels were encapsulated using a hot press bonding
technique. The experimental results showed that both discrete droplets and laminar flows could be obtained in the device. 相似文献
2.
3.
Nearest and reverse nearest neighbor queries for moving objects 总被引:4,自引:0,他引:4
Rimantas Benetis Christian S. Jensen Gytis Karĉiauskas Simonas Ŝaltenis 《The VLDB Journal The International Journal on Very Large Data Bases》2006,15(3):229-249
With the continued proliferation of wireless communications and advances in positioning technologies, algorithms for efficiently
answering queries about large populations of moving objects are gaining interest. This paper proposes algorithms for k nearest and reverse k nearest neighbor queries on the current and anticipated future positions of points moving continuously in the plane. The
former type of query returns k objects nearest to a query object for each time point during a time interval, while the latter returns the objects that have
a specified query object as one of their k closest neighbors, again for each time point during a time interval. In addition, algorithms for so-called persistent and
continuous variants of these queries are provided. The algorithms are based on the indexing of object positions represented
as linear functions of time. The results of empirical performance experiments are reported. 相似文献
4.
Farah Perveen Mughal Ann Christina Bergmann Ha Uyen Buu Huynh Sarah Hyllekvist Jrgensen Inaam Mansha Meliha Kesmez Patrick Mark Schürch Alexandre Pierre Andr Theocharides Paul Robert Hansen Tina Friis Morten Orebo Holmstrm Evaldas Ciplys Rimantas Slibinskas Peter Hjrup Gunnar Houen Nicole Hartwig Trier 《International journal of molecular sciences》2022,23(12)
Myeloproliferative Neoplasms (MPNs) constitute a group of rare blood cancers that are characterized by mutations in bone marrow stem cells leading to the overproduction of erythrocytes, leukocytes, and thrombocytes. Mutations in calreticulin (CRT) genes may initiate MPNs, causing a novel variable polybasic stretch terminating in a common C-terminal sequence in the frameshifted CRT (CRTfs) proteins. Peptide antibodies to the mutated C-terminal are important reagents for research in the molecular mechanisms of MPNs and for the development of new diagnostic assays and therapies. In this study, eight peptide antibodies targeting the C-terminal of CRTfs were produced and characterised by modified enzyme-linked immunosorbent assays using resin-bound peptides. The antibodies reacted to two epitopes: CREACLQGWTE for SSI-HYB 385-01, 385-02, 385-03, 385-04, 385-07, 385-08, and 385-09 and CLQGWT for SSI-HYB 385-06. For the majority of antibodies, the residues Cys1, Trp9, and Glu11 were essential for reactivity. SSI-HYB 385-06, with the highest affinity, recognised recombinant CRTfs produced in yeast and the MARIMO cell line expressing CRTfs when examined in Western immunoblotting. Moreover, SSI-HYB 385-06 occasionally reacted to CRTfs from MPN patients when analysed by flow cytometry. The characterized antibodies may be used to understand the role of CRTfs in the pathogenesis of MPNs and to design and develop new diagnostic assays and therapeutic targets. 相似文献
5.
Arunas Augustinaitis Richard Ennals Egle Malinauskiene Rimantas Petrauskas 《AI & Society》2009,23(1):41-50
The paper reflects on the unique experience of social and technological development in Lithuania since the regaining of independence
as a newly reshaped society constructing a distinctive competitive IST-based model at global level. This has presented Lithuanian
pattern of how to integrate different experiences and relations between generations in implementing complex information society
approaches. The resulting programme in general is linked to the Lisbon objectives of the European Union. The experience of
transitional countries in Europe, each different but facing some common problems, may be useful to developing countries in
Africa.
相似文献
Arunas Augustinaitis (Corresponding author)Email: |
Richard EnnalsEmail: |
Egle MalinauskieneEmail: |
Rimantas PetrauskasEmail: |
6.
Several toxicological indices currently proposed (inter)nationally to aid decision-making tasks in effluent control were compared. To evaluate effluent ranking differences between the indices an inversion distance as a similarity measure was proposed. The major factor influencing effluent ranking were found to be a composition of test-battery. Differences in mathematical operator of the indices such as, e.g. arithmetic mean (used in averaging indices) or maximum one (used in an approach of the most sensitive test in a battery), affect the ranking similarity noticeably lesser than the modification of the percentage effect level of the measurement endpoints. Effluent and/or river flow parameters incorporated into the indices substantially modify ranking results of the effluent set. For the analysis, the toxicological information on 23 effluents from municipal wastewater treatment plants operating in cities and small towns of Lithuania as well as test-battery data on industrial effluents published elsewhere were used. It seems that the general statements achieved in the current study can be applied to any set of effluents. 相似文献
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8.
Ieva Raudoniūtė Jordi Rovira Petras Rimantas Venskutonis Jonas Damašius María Dolores Rivero‐Pérez María Luisa González‐SanJosé 《International Journal of Food Science & Technology》2011,46(5):935-943
The present study characterises garden strawberry leaf extract and reports its effect on shelf life and quality characteristics of fish oil. Radical scavenging capacity of the extract in DPPH? and ABTS?+ assays was equivalent to 1207 and 1579 μmol g?1 of trolox equivalents, respectively, total phenolic content was 257 mg g?1 of gallic acid equivalents. Phenolic and volatile constituents were analysed by liquid chromatography/mass spectrometry (LC/MS) and gas chromatography/mass spectrometry (GC/MS). The extract was added to fish oil and its oxidation was followed during 42 days: peroxide, p‐anisidine values and hexanal concentration were lower in the samples with extract, particularly at the end of storage. The effect of extract on fatty acid composition was not significant, however the changes in the percentages of some individual acids were observed. Fish oil containing 5% of extract had lower levels of lipid oxidation in comparison to other samples. The results indicate that strawberry leaves could be a potential source of natural antioxidants. 相似文献
9.
Rimantas Pupeikis 《International Journal of Adaptive Control and Signal Processing》2021,35(6):941-964
The paper considers a block-oriented nonlinear Hammerstein system that consists of a linear block with real-valued time-varying unknown coefficients and a pure time delay, preceded by the static nonlinearity. The joint tracking of linear block coefficients and the time delay while processing observation samples is under consideration. The difficulty of the tracking process consists in the initial nonconvexity of the objective function to be minimized, in respect of the time delay. To obtain current estimates of the true coefficients and the time delay it is necessary to overcome the multiextremality of the objective function. A global optimization problem could be solved by changing a form of the nonconvex objective function into a convex one. The optimization problem has been subdivided into two problems that are analyzed in this article, as well. The first one consists of removal of the objective function multiextremality in respect of the time delay, while hunting for the global extremum. Therefore, the well-known approach based on the method of corrective operators, which is used to transform the multiextremal criterion into a unimodal function for the nonstationary Wiener system, is developed here for the Hammerstein one. The other problem consists of the applicability of unified adaptive algorithms, used for Wiener systems in the case of Hammerstein systems. The recursive parametric identification technique, based on the adaptive algorithm procedures, is developed here for the nonstationary block-oriented Hammerstein systems, too. The applicability of algorithms is supported by various simulation tests solved by computer for distinct inputs and for two static nonlinearities. 相似文献
10.