Synthesis and characterization of radiation cross-linked PVP hydrogels and investigation of its potential as an antileishmanial drug carrier

Polymer Bulletin - The aim of this study was to elaborate a suitable hydrogel to be used as drug carrier for antileishmanial treatment. Therefore, a PVP hydrogel was synthesized using gamma...     

Experimental investigation and numerical simulation analysis of sintered micro-fluidic devices

ABSTRACT

This study investigates the use of numerical simulations to describe the solid-state diffusion of a sintering stage during a metal injection moulding process for micro-fluidic components with 316L stainless steel powders. Finite element (FE) analysis based on a thermo-elasto-viscoplastic model was conducted to describe the densification process of a stainless steel porous component during solid-state sintering. The numerical analyses, which were performed on a 3D micro-structured component with various powder volume loadings to take into account the thermal debinding effect to propose a full debinding sintering simulation, demonstrated that the FE simulation results are in agreement with the experimental ones.     

Manufacturing and replication of glass pyramidal micro-structures by using the injection moulding process

The aim of this work is to perform experimental investigations related to the different injection moulding conditions required for the proper replication of glass structures. The paper investigates the thermal and rheological characterisations of the feedstock. This study demonstrates that the structured shapes could be successfully injected in the structured metallic mould with pyramidal shapes, with suitable forming parameters. After sintering, the experiment results confirm that the components exhibit anisotropic shrinkage in range from 10 to 20?%.     

A bigraphical model for specifying cloud-based elastic systems and their behaviour

The few recent years have witnessed the appearance of a new kind of self-adaptive systems called cloud based-elastic systems. These systems are particularly appealing for their ability to maintain a decent quality of service and reduce a system’s operating cost at the same time. They achieve this by dynamically adjusting resources allocation in terms of elasticity. Meanwhile, complexity of structural and behavioural aspects related to cloud-based elastic systems increase the difficulty of designing and developing such systems. In this paper, we address this challenge by proposing a formal approach based on bigraphical reactive systems for modelling both structural and behavioural aspects of cloud-based elastic systems. In particular, we represent their behaviour in terms of client/application interactions and elasticity methods at different levels using bigraphical reaction rules. The feasibility of the proposed approach is illustrated through a motivating example running on the top of an Amazon Elastic Compute Cloud (EC2) infrastructure.     

Extracting TSK-type Neuro-Fuzzy model using the Hunting search algorithm

This paper proposes a Takagi-Sugeno-Kang (TSK) type Neuro-Fuzzy model tuned by a novel metaheuristic optimization algorithm called Hunting Search (HuS). The HuS algorithm is derived based on a model of group hunting of animals such as lions, wolves, and dolphins when looking for a prey. In this study, the structure and parameters of the fuzzy model are encoded into a particle. Thus, the optimal structure and parameters are achieved simultaneously. The proposed method was demonstrated through modeling and control problems, and the results have been compared with other optimization techniques. The comparisons indicate that the proposed method represents a powerful search approach and an effective optimization technique as it can extract the accurate TSK fuzzy model with an appropriate number of rules.     

Physicochemical properties of fermented Arabian mares' milk

Due to its numerous benefits, including health-promoting characteristics, there is increasing interest in finding product applications for mares' milk. In the present study, the physicochemical properties, turbidity and conductivity of Arabian mares' milk were studied during acidification by fermentation at 30 °C and compared with those of bovine milk. The data for the acidification rate were modelled using a logistic equation. Mares' milk showed a longer latency phase (284 min) and lower acidification rate (μ_max = 0.0052 dpH min^?1) compared with bovine milk (194 min and 0.0098 dpH min^?1 respectively). The general shape of the curves of the turbidity versus time and pH were similar in nature for the acidification of both milks. However, the characteristic points were different, due to the differences in casein micelle composition. Measurement of electrical conductivity during acidification showed that maximum demineralization of casein micelles started around pH 6.09 and 5.31, for mares' and bovine milk, respectively. In conclusion, the technological characteristics of mares' milk were very different from those of bovine milk, due to intrinsic physicochemical properties of both milks.