Tests of a Two-Stage Core at the KV-1 Test Facility: Physical Aspects and Results

Atomic Energy - The physical aspects and main results of reactor tests of a two-stage core consisting of fresh fuel assemblies and a significant number of fuel assemblies from the previous core,...     

Some Molecular and Cellular Stress Mechanisms Associated with Neurodegenerative Diseases and Atherosclerosis

Chronic stress is a combination of nonspecific adaptive reactions of the body to the influence of various adverse stress factors which disrupt its homeostasis, and it is also a corresponding state of the organism’s nervous system (or the body in general). We hypothesized that chronic stress may be one of the causes occurence of several molecular and cellular types of stress. We analyzed literary sources and considered most of these types of stress in our review article. We examined genes and mutations of nuclear and mitochondrial genomes and also molecular variants which lead to various types of stress. The end result of chronic stress can be metabolic disturbance in humans and animals, leading to accumulation of reactive oxygen species (ROS), oxidative stress, energy deficiency in cells (due to a decrease in ATP synthesis) and mitochondrial dysfunction. These changes can last for the lifetime and lead to severe pathologies, including neurodegenerative diseases and atherosclerosis. The analysis of literature allowed us to conclude that under the influence of chronic stress, metabolism in the human body can be disrupted, mutations of the mitochondrial and nuclear genome and dysfunction of cells and their compartments can occur. As a result of these processes, oxidative, genotoxic, and cellular stress can occur. Therefore, chronic stress can be one of the causes forthe occurrence and development of neurodegenerative diseases and atherosclerosis. In particular, chronic stress can play a large role in the occurrence and development of oxidative, genotoxic, and cellular types of stress.     

Pseudosound Pressure Oscillations Caused By the Interaction of a Fluid Flow with the Obstacle in the Form of a Circular Cylinder in a Pipe

Journal of Engineering Physics and Thermophysics - A simulation of the vibroacoustic processes proceeding in a long pipe with an obstacle in the form of a circular cylinder, in which a fluid flows,...     

Simulation of Silicon Carbide Sputtering by a Focused Gallium Ion Beam

Semiconductors - The precision fabrication of microstructures and nanostructures by the focused-ion-beam method is significantly simplified by the simulation of sputtering of materials by...     

Properties of a Ceramic Pyroelectric X-Ray Generator as Dependent on Residual-Gas Pressure

The properties of X-ray emission from a pyroelectric accelerator based on ferroelectric ceramics have been experimentally studied, including the maximum energy of X-ray photons and their maximum yield generated by accelerated electrons at various pressures of residual gas in the generator chamber. The maximum X-ray yield and maximum energy of X-ray photons and accelerated electrons have been observed at a residual-gas pressure of around several millitorr.     

Interaction of Microelements at Coprecipitation with Humic Acids

Radiochemistry - Through the example of the sorption-coprecipitation data for microelements simulating the corrosion, activation, and fission products, the nature of the isotherms of sorption of...     

Interaction of Humic Acids with Microelements/Radionuclides in Sorption Systems

Radiochemistry - Modern state of research in the field of physical chemistry of the complexation of humic acids with cations, including radio nuclides, in aqueous solutions is considered....     

Digital Twins,Internet of Things and Mobile Medicine: A Review of Current Platforms to Support Smart Healthcare

Programming and Computer Software - As the population grows, the need for higher-quality medical services increases, as well as the demand for information technology in medicine. The Smart...