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排序方式: 共有57条查询结果,搜索用时 15 毫秒
1.
利用杆状病毒表面展示技术,构建展示SARS-CoV的棘突蛋白(spike protein)受体结合结构域(receptor binding domain,RBD)的重组杆状病毒vBmgp64-RBD,并进一步研究其展示目的蛋白的免疫原性。结果表明:RBD蛋白正确表达并成功展示在病毒囊膜表面,将灭活的纯重组杆状病毒vBmgp64-RBD皮下注射BALB/c小鼠能产生抗RBD蛋白的特异性抗体,且抗体具有抗RBD蛋白的中和作用。证明vBmgp64-RBD有可能作为一种基于杆状病毒的新型SARS疫苗,为SARS的体外检测及后续疫苗的研究开发奠定了基础。 相似文献
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P.M. Herder J.A. van Luijk J. Bruijnooge 《Reliability Engineering & System Safety》2008,93(4):501-508
A RAM (reliability, availability and maintenance) model has been built for the GE Industrial, Plastics Lexan® plant in Bergen op Zoom, The Netherlands. It was based on a Reliability Block Diagram with a Monte Carlo simulation engine. The model has been validated against actual plant data from two different sources, and against local expert opinions, resulting in a satisfactory simulation model. The model was used to assess two key decisions that were (to be) made by GE Industrial, Plastics concerning operation and shutdown policies of the plant. The model results showed that the operation and maintenance could be further improved, and that in doing so the annual production loss could be reduced further. 相似文献
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随着城市经济的发展和人们游憩时间的增多.城市游憩商业区(RBD)建设越来越受重视。选取发展相对成熟的南京夫子庙RBD作为研究对象.通过问卷调查获得游憩者需求数据.采用主成分分析法对南京夫子庙RBD的游憩需求进行分析.得出其游憩需求主要为精神需求、智力需求商品需求、购物环境需求、缓解压力需求和社会交际需求6个方面.并运用功能密度指数对南京夫子庙RBD的功能结构特点进行探讨.发现其存在忽视旅游功能建设、功能集聚程度不够等方面的不足.进而提出如何根据游憩者的需求改善夫子庙RBD功能结构的建议。 相似文献
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The wide use of petroleum-based oils raises concerns with regard to pollution, and the rising of awareness of greenhouse gases has created a demand for the use of environmentally friendly and biodegradable lubricants for industrial applications. Vegetable oils are one of the bio-oils that have been promoted as a replacement for petroleum products, in part due to their environmentally friendly characteristics; they are nontoxic, biodegradable, and easy to dispose of. Many researchers have performed studies on sunflower oil, corn oil, and soy oil, but few have studied palm oil as a lubricant. Palm oil produced in a high-throughput manner could fulfill the demand for bio-based lubricants. In this study, the influence of temperature on friction and wear performance for refined, bleached, and deodorized (RBD) palm stearin and additive-free paraffinic mineral oil is presented. The experiments were conducted using a four-ball tribotester. Test temperatures of 55, 65, 75, and 85°C were used. The sliding speeds were set to 1,200 rpm. Experiments were run for 1 h under a 392.4 N load. The results of RBD palm stearin were compared with those of paraffinic mineral oil. The experimental results showed that the RBD palm stearin had better performance compared to paraffinic mineral oil in terms of reducing frictional constraints. 相似文献
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"The RBD III, a forced-choice rating form to provide scores indicative of a person's productive research behavior in physical science research settings, was administered in a setting other than the one in which it was developed." 50 Ss were selected at random from 168 research engineers. Supervisory judgments of a person's creativity activity indicated its validity. The "RBD III can be used to provide criterion scores for research productivity in other physical science research settings." (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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RBD对老城区功能改造的模式研究 总被引:1,自引:0,他引:1
随着体验经济时代的到来和新城市主义的兴起,城市新老城区的协调发展问题被提上了议事日程,尤其是老城区的功能改造已成为我国城市发展进程中迫切需要解决的突出问题。在RBD理论研究日益成熟和实践经验日益丰富的条件下,特色步行街作为老城区功能改造的一种流行模式已表现出明显的局限性,迫切需要进行RBD模式的创新与发展。为此,可遵循用差异激活个性的老城区功能改造理念,采用文化社区、休闲社区、娱乐社区、主题公园和主题街区五种RBD创新模式。 相似文献