The effect of short cardio on inhibitory control ability of obese people

To study the effect of short cardio on obese male college students’ inhibitory control ability, we investigate difference on brain activation patterns before and after short cardio by analyzing the resting state fMRI data. The experiment results of this study show that short cardio can improve the inhibitory control ability of obese people.     

Analyzing fatigue in prolonged watching of 3DTV with ReHo approach

Fatigue caused by the prolonged watching of 3DTV has been paid great attention about the safety for viewers. We used regional homogeneity (ReHo) to measure the local synchronization of resting‐state functional magnetic resonance imaging signals both before and after watching 2D or 3D television. Twenty normal subjects were all measured four times: scans before watching television (3D‐Pre/2D‐Pre) and immediately after watching television for 1 h (3D‐Post/2D‐Post). The variation of ReHo was investigated in 2D/3D groups, and then the influence of watching 2D/3D TV on the spectators was estimated. Compared with the 3D‐Pre, the 3D‐Post showed significantly higher ReHo in the right inferior occipital gyrus (BA18/19) and right middle occipital gyrus (BA18/19), left postcentral gyrus (BA2/3/4/7), and small area of BA9/10 in left frontal lobe. Additionally, increased ReHo regions in the 2D‐Post was observed in the left medial frontal gyrus (BA9/10/32), left cingulate gyrus (BA24), and right anterior cingulate (BA32) as compared with the 2D‐Pre. For the 2D group, subjects mainly feel mental fatigue, which could be caused by prolonged attention. For the 3D group, watching TV primarily causes visual fatigue because of the constant change of depth of focus and mild mental fatigue. The study indicates the adverse effects of 3DTV on visual function.     

2型糖尿病视网膜病变功能磁共振成像研究

为了探讨在静息状态下2型糖尿病引发的视网膜病变的脑部活动情况,对21名性别、年龄、文化程度相近的2型糖尿病视网膜病变(type 2 diabetes mellitus retinopathy,T2DR)患者和与之对应的16名正常志愿者(normal control,NC)在静息态下进行脑部扫描.分别用低频振幅(amplitude of low frequency fluctuation,ALFF)和局部一致性(regional homogeneity,ReHo)的脑功能磁共振成像方法(functional magnetic resonance imaging,fMRI)处理所得的fMRI数据,对ALFF和ReHo两种方法所得的数据分别进行双样本T-检验,两种方法结合起来比较正常人和病人的脑功能活动之间的差异,并对结果进行分析.经过双样本T-检验之后的结果显示(与NC组相比):ALFF显著增高的脑区有右侧舌回、枕叶和楔叶(p＜0.001,体素值＞30),ALFF显著降低的脑区有右侧小脑后叶、小脑前叶、缘叶、海马旁回、梭状回、颞上回、顶下小叶、角回;ReHo显著增高的脑区有右侧舌回和枕叶,ReHo显著降低的脑区有左侧后扣带回、缘叶、右侧顶下小叶、颞上回、海马、枕叶.结论显示2型糖尿病视网膜病变患者静息态脑功能存在明显异常,ALFF和ReHo的联合运用可以有助于2型糖尿病视网膜病变患者的脑功能状况的研究.     

基于局部一致性的特征选取及在抑郁症上的研究

为探讨局部一致性ReHo(regional homogeneity)是否可以作为有效诊断抑郁症的特征,且其统计显著性是否可以作为有效的筛选标准并进行相应的分类。对28例正常人和38例抑郁症患者进行静息态全脑f MRI(functional Magnetic Resonance Imaging)扫描并分析。使用具有统计显著性的阈值作为筛选特征的标准并度量四种分类器下的正确率,运用敏感性分析方法评估不同特征的重要性,以此来构建一个准确率较高的模型。结果在SVM-RBF和神经网络算法中,当特征数为30时表现出了较高的正确率,分别是77.4%和73.1%。在研究特征重要性和统计显著性之间的相关性分析中,发现二者具有明显的正相关。因此,可以利用该方法用在抑郁症的诊断当中。