Type II fuzzy set-based data analytics to explore amino acid associations in protein sequences of Swine Influenza Virus

The veracity present in molecular data available in biological databases possesses new challenges for data analytics. The analysis of molecular data of various diseases can provide vital information for developing better understanding of the molecular mechanism of a disease. In this paper, an attempt has been made to propose a model that addresses the issue of veracity in data analytics for amino acid association patterns in protein sequences of Swine Influenza Virus. The veracity is caused by intra-sequential and inter-sequential biases present in the sequences due to varying degrees of relationships among amino acids. A complete dataset of 63,682 protein sequences is downloaded from NCBI and is refined. The refined dataset consists of 26,594 sequences which are employed in the present study. The type I fuzzy set is employed to explore amino acid association patterns in the dataset. The type I fuzzy support is refined to partially remove the inter-sequential biases causing veracity in data. The remaining inter-sequential biases present in refined fuzzy support are evaluated and eliminated using type II fuzzy set. Hence, it is concluded that a combination of type II fuzzy & refined fuzzy approach is the optimal approach for extracting a better picture of amino acid association patterns in the molecular dataset.     

Cryptosporidium Log-inactivation with Ozone Using Effluent CT10, Geometric Mean CT10, Extended Integrated CT10 and Extended CSTR Calculations

The draft Long-Term 2 Enhanced Surface Water Treatment Rule (LT2ESWTR) contains Cryptosporidium log-inactivation CT tables (ozone-in-water concentration [residual], “C” times contact time, T). Depending on water temperature, Cryptosporidium CT values that are listed are 15 to 25 times greater than CT values for equivalent Giardia log-inactivation credit. The elevated operating dose required for Cryptosporidium log-inactivation credit has the potential to increase disinfection by-product (DBP) formation (e.g., bromate). Calculating CT value accurately will minimize ozone dose, which will decrease operating cost and lower DBP formation, and at the same time maintain disinfection protection through implementation of scientifically based safety factors. Various methods are available for calculating CT value. The method chosen depends largely on the available information concerning ozone residual characteristics and hydrodynamic features of the ozone contactor, plus local regulatory requirements. Four methods are discussed in this paper. Each method can be used to calculate Giardia, virus, and Cryptosporidium log-inactivation credit.     

浅谈计算机局域网病毒及防范策略

简述了计算机局域网的病毒的类型,并提出了相应的防范策略。     

如何做好电子阅览室的安全管理

防治病毒、防混乱和防泄密是图书馆电子阅览室安全管理中三个最主要的环节，本文针对这三个主要环节，提出了一些比较实用的具体方法及措施。     

重组人干扰素α2b阴道泡腾片抗豚鼠单纯疱疹病毒性阴道炎的疗效

目的观察重组人干扰素α2b阴道泡腾片对单纯疱疹病毒性阴道炎动物模型的疗效。方法采用单纯疱疹病毒感染建立豚鼠实验性阴道炎模型,并分别用重组人干扰素α2b阴道泡腾片600、3 000和15 000 IU/只进行治疗。以阿昔洛韦(无环鸟苷)和干扰素α2b栓剂15 000 IU/只作为对照。对治疗前后豚鼠阴道外观及组织切片进行评分。结果应用重组人干扰素α2b阴道泡腾片对豚鼠实验性单纯疱疹病毒性阴道炎进行治疗后,豚鼠阴道外观病变与组织切片病变评分均显著降低,其中15 000 IU/只效果最好。同样剂量的α2b泡腾片药效优于栓剂。结论重组人干扰素α2b阴道泡腾片对实验性单纯疱疹病毒性阴道炎有明显的疗效。     

Ozone in the Laundry Industry—Practical Experiences in the United Kingdom

Since the early 1990s, the use of ozone in many commercial and industrial laundering applications has been evolving rapidly. Ozone allows washing to be conducted using cold water, thereby saving considerable heat energy and water consumption. Additionally, ozone enhances the wash process, resulting in a significant reduction in detergent dosage and number of rinses, thus saving water. Ozone/cold water cycles are gentler to fabrics, thus extending linen life. Finally, ozone/cold water laundering is beneficial for effluents, resulting in reductions in COD (chemical oxygen demand). Microorganisms are destroyed effectively in ozone-wash waters, and washing and drying cycles are shorter, thus saving labor. In this paper, the authors describe some specific case studies at commercial laundering installations in the UK, whereby the users of ozone have reaped major benefits, including enhanced microorganism kills/inactivation and significant cost savings.     

Vero细胞森林脑炎疫苗毒种的选育及其生物学特性检测

目的选育Vero细胞森林脑炎疫苗适应毒种。方法将森林脑炎疫苗鼠脑病毒“森张”株在Vero细胞上连续传代适应,并对不同代次收获的病毒液的病毒滴度、免疫原性、稳定性等进行检测。结果“森张”株病毒在Vero细胞上传代适应后,病毒滴度达8·5LgLD50/ml;免疫血清中和抗体效价高于1∶20,其它检测项目均符合疫苗生产用毒种的要求。结论Vero细胞适应的“森张”株毒种的初步特性显示可作为制备Vero细胞森林脑炎疫苗用毒种。     

云计算数据服务主动安全防御系统探讨

随着云计算数据服务的快速发展和应用,大大地改变了人们的工作、学习和生活模式。云计算数据服务带来极大便利的同时,也给人们带来了潜在的威胁,因此需要构建网络安全主动防御系统,提高网络安全性能。文章详细地分析了云计算数据服务面临的安全威胁,阐述了云计算服务平台主动安全防御系统及采用的技术,提高了云计算数据服务平台的安全性能。     

甲肝和麻疹病毒混合感染人胚肺二倍体细胞病毒增殖动态及与细胞相互作用的研究

目的　探讨甲肝病毒 (HAV)和麻疹病毒 (MV)混合感染人胚肺二倍体细胞 2BS株 (2BS)病毒增殖动态及病毒与细胞相互作用的关系 ,为制备甲肝 -麻疹二联活疫苗提供基础资料。方法　将HAV和MV先后感染2BS ,应用细胞病理学、亲和素 生物素系统免疫组化技术和电镜技术检测HAV和MV在 2BS内增殖动态及 2种病毒与细胞的相互关系 ,观察HAV和MV在细胞内的超微结构。结果　HAV和MV能在同一种细胞基质中增殖 ,也能在同一个细胞中增殖 ,但 2种病毒与细胞的相互作用明显不同。结论　HAV对MV的再感染似乎无明显干扰现象     

浅谈AutoRun.inf计算机病毒的防治

通过对AutoRun.inf计算机病毒特点的分析及Coes病毒的研究,得出AutoRun.inf计算机病毒的清除方法和预防措施。