排序方式: 共有53条查询结果,搜索用时 15 毫秒
1.
Brett J. Kagan Charlotte M. Ermine Stefano Frausin Clare L. Parish Jess Nithianantharajah Lachlan H. Thompson 《International journal of molecular sciences》2021,22(9)
Neonatal arterial ischemic stroke is one of the more severe birth complications. The injury can result in extensive neurological damage and is robustly associated with later diagnoses of cerebral palsy (CP). An important part of efforts to develop new therapies include the on-going refinement and understanding of animal models that capture relevant clinical features of neonatal brain injury leading to CP. The potent vasoconstrictor peptide, Endothelin-1 (ET-1), has previously been utilised in animal models to reduce local blood flow to levels that mimic ischemic stroke. Our previous work in this area has shown that it is an effective and technically simple approach for modelling ischemic injury at very early neonatal ages, resulting in stable deficits in motor function. Here, we aimed to extend this model to also examine the impact on cognitive function. We show that focal delivery of ET-1 to the cortex of Sprague Dawley rats on postnatal day 0 (P0) resulted in impaired learning in a touchscreen-based test of visual discrimination and correlated with important clinical features of CP including damage to large white matter structures. 相似文献
2.
针对组合机床的运动特点,采用多台SDPLC单轴控制系统实现对转台式多工位组合机床的数字化控制,应用系统提供的PLC程序及STEP程序完成组合机床的逻辑控制及加工运动,通过对控制系统通讯功能的开发,利用ADP软件依据人机通讯地址所需求的转换关系,在触摸屏上完成满足用户需求的人机界面设计. 相似文献
3.
《Ergonomics》2012,55(8):733-744
An experimental study was conducted to evaluate physical risk factors associated with the use of touchscreen in a desktop personal computer (PC) setting. Subjective rating of visual/body discomfort, shoulder and neck muscle activity, elbow movement and user-preferred positions of the workstation were quantified from 24 participants during a standardised computer use task with a standard keyboard and a mouse (traditional setting), with a touchscreen and the standard keyboard (mixed-use condition) and with the touchscreen only. The use of a touchscreen was associated with a significant increase of subjective discomfort on the shoulder, neck and fingers, myoelectric activity of shoulder and neck muscles and percentage of task duration that arms were in the air. Participants placed the touchscreen closer and lower when using touch interfaces compared with the traditional setting. Results suggest that users would need more frequent breaks and proper armrests to reduce physical risks associated with the use of a touchscreen in desktop PC settings. Statement of Relevance: In this study, subjective discomfort, work posture and muscle activity of touchscreendesktop PC users were quantitatively evaluated. The findings of this study can be used to understand potential risksfrom the use of a touchscreen desktop PC and to suggest design recommendations for computer workstations with the touchscreen. 相似文献
4.
5.
6.
7.
8.
根据公路隧道的特点,提出了一种基于PLC及触摸屏技术的隧道通风控制系统的设计。将PLC、触摸屏、变频器三者有效结合,利用传感器在实时检测隧道内环境的基础上,通过PLC控制变频器驱动隧道内风机的运行,优化隧道内空气质量的同时也节约了能源。触摸屏的引入能够实现对系统工作全程的实时自动监控,最后利用计算机模拟技术实现了对该控制系统的整体模拟和调试。实验证明,该系统运行顺畅,性能可靠,人机交互界面友好,自动化水平有效提高,具有良好的市场前景及应用价值。 相似文献
9.
10.