Clinical significance of contact lens related changes of ocular surface tissue observed on optical coherence images

PurposeTo investigate the relationship between the real contact lens imprint into the conjunctival tissue, observed by optical coherence tomography (OCT) and conjunctival staining and contact lens wearing comfort.Methods17 participants (mean age = 26.6 SD ± 3.6 years; 7 females) were fitted with three different contact lenses base curves of the same silicone hydrogel custom lens type (Visell 50; Hecht Contactlinsen, Au, Germany) in a randomised order. One lens was optimally fitted according to the manufacturer's recommendation, one fitted 0.4 mm flatter and one fitted 0.4 mm steeper. After 4 h of lens wear the contact lens edge in the area of the conjunctiva was imaged nasally and temporally using OCT (Optovue iVue SD-OCT). To correct the artefact due to optical distortion with OCT, the imprint of all worn lenses was measured on a glass plate afterwards. Conjunctival staining in the limbal region after 4 h of lens wear was classified using the CCLRU Grading Scale. Comfort scoring was based on visual analog scales from 0 (very poor) to 100 (excellent).ResultsThe mean conjunctival imprint of all contact lens edges was 32.0 ± 8.1 μm before and 7.3 ± 6.5 μm after distortion correction of the OCT images. The distortion corrected conjunctival imprint with the 0.4 mm steeper lens (11.5 ± 6.2 μm) was statistically significantly greater compared to the optimally fitted lens (6.5 ± 5.9 μm) (One-way ANOVA followed Tukey-test; p = 0.017) and greater compared to the 0.4 mm flatter lens (3.9 ± 5.3 μm) (p < 0.001). There was no statistically significant difference between the optimally fitted lens and the 0.4 mm flatter lens (p = 0.209). The nasally measured imprint (11.4 ± 9.0 μm) was significantly greater than the temporally measured (3.3 ± 7.6 μm) (p < 0.001). There was no statistically significant correlation between the amount of conjunctival imprint and the graded conjunctival staining (p = 0.346) or the wearer’s comfort (p = 0.735).ConclusionsContact lens edges imaged by OCT exhibited displacement artefacts. The observed conjunctival imprints are a combination of real conjunctival compression and artefacts. A deeper imprint of the contact lens into the conjunctiva caused by a steeper base curve was not related to clinically significant staining or changes in comfort after 4 h of lens wear. The observed differences between nasal and temporal imprint are likely to be caused by variations of conjunctival thickness and the shape of the underlying sclera.     

一种PD雷达动目标模拟与微波测控系统

介绍了一种基于PC／104总线，具有GPIB程控功能，采用无内部微波源体制，通过在雷达载频上调制多普勒频率模型目标速度信息，延迟雷达发射机触发脉冲模拟目标距离信息并具有微波功率精确定标与衰减功能的PD雷达动目标模拟与微波测控系统。     

OCT图像散斑的形成机理和清除方法

根据光相干层析成像（OCT）的光学和光电检测系统特点，结合现有的理论模型，分析了OCT成像和散斑形成机理。指出失去相干性的多次散射光部分会被滤波电路排除，散斑是由高散射组织相干长度之内的不同散射截面上的若干具有nπ光程差的相干散射光彼此叠加形成的。最后讨论了消除散斑的方法。     

用于提高国产氩离子激光器相干长度的相干扩展器

本文报导了最近研制成功的用于提高国产氩离子激光器相干长度的相干扩展器。利用这种基于F-P理论的相干扩展器可以使国产氩离子激光器的相干长度由不足5cm一下提高到m的量级,功率损耗在25%～40%之间,有着很好的应用前景。     

相干分析技术在泥岩裂缝油气藏预测中的应用

胜利油田罗家地区泥岩裂缝油气藏多发育在含灰质的油泥岩、油页岩等特殊的岩相带，并且以构造裂缝为主，与断层关系密切，进行泥岩裂缝油气藏地震相分析和断层的精细描述是预测泥岩裂缝油气藏的关键。结合工区的真体地质特点，运用相干分析技术，预测了泥岩裂缝发育的有利沉积相带和精细断裂系统特征，为该区泥岩裂缝的综合描述提供了依据。     

GH2027铁基高温合金的第二相研究

运用电子显微分析和波谱分析等方法对ＧＨ２０２７合金的第二相进行了研究，结果表明，合金晶界相主要是片状Ｍ６Ｃ和薄膜状Ｍ２３Ｃ６，经波纹图样测得其错配度约为３％，晶内Ｍ６Ｃ和Ｍ２３     

裂缝性潜山储层地震描述技术

裂缝是潜山油气藏的重要储集层 ,潜山的油气产出与裂缝的发育情况密切相关 ,因此 ,对裂缝发育控制因素和裂缝发育规律进行了分析和探讨。尽管单条裂缝在地震资料上难以识别 ,但是裂缝带在地震资料上有其特征。描述了裂缝储层的地球物理特征 ,并利用测井约束反演技术、吸收系数技术、地震相分类和相干分析技术对潜山储层进行预测。通过在车古 2 0 1潜山的应用实例分析 ,说明以上 4种储层描述技术比较有效     

Experience with Applying Formal Methods to Protocol Specification and System Architecture

In the last three years or so we at Enterprise Platforms Group at Intel Corporation have been applying formal methods to various problems that arose during the process of defining platform architectures for Intel's processor families. In this paper we give an overview of some of the problems we have worked on, the results we have obtained, and the lessons we have learned. The last topic is addressed mainly from the perspective of platform architects.     

超Jaynes-Cummings模型中的原子置于热辐射场时的相干特性

超Jaynes一Cummings模型中的两能级原子置于热辐射场。通过求解原子与热辐射场相互作用过程中原子约化密度算符非对角元．精确得出子原子相干性的衰变规律。研究了在相互作用系统中外加驱动场时可保持原子的相干性，此时外加驱动场的时间演化与原子的跃迁频率、原子偶极矩、热库的温度和k模光子频率等因素有关。     

曲流河沉积亚相的地震识别方法

本文提出利用三维地震资料相干数据分析研究曲流河沉积相的方法，其优点是在地质分析的基础上，对沉积体系有较为明显的识别特征，且在钻井较少的地区尤为实用。该方法在济阳拗陷东北部上第三系应用中取得了较为明显的效果。